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Author Babiano, V.; Balibrea, J.; Caballero, L.; Calvo, D.; Ladarescu, I.; Mira Prats, S.; Domingo-Pardo, C.
Title First i-TED demonstrator: A Compton imager with Dynamic Electronic Collimation Type Journal Article
Year 2020 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 953 Issue Pages (up) 163228 - 9pp
Keywords Compton imaging; Position-sensitive detectors; Monolithic crystals; Silicon photomultiplier
Abstract i-TED consists of both a total energy detector and a Compton camera primarily intended for the measurement of neutron capture cross sections by means of the simultaneous combination of neutron time-of-flight (TOF) and gamma-ray imaging techniques. TOF allows one to obtain a neutron-energy differential capture yield, whereas the imaging capability is intended for the discrimination of radiative background sources, that have a spatial origin different from that of the capture sample under investigation. A distinctive feature of i-TED is the embedded Dynamic Electronic Collimation (DEC) concept, which allows for a trade-off between efficiency and image resolution. Here we report on some general design considerations and first performance characterization measurements made with an i-TED demonstrator in order to explore its gamma-ray detection and imaging capabilities.
Address [Babiano, V; Balibrea, J.; Caballero, L.; Calvo, D.; Ladarescu, I; Mira Prats, S.; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: domingo@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000506419900045 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4250
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Author Balibrea-Correa, J.; Lerendegui-Marco, J.; Babiano-Suarez, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros-Rodriguez, P.; Domingo-Pardo, C.
Title Machine Learning aided 3D-position reconstruction in large LaCl3 crystals Type Journal Article
Year 2021 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 1001 Issue Pages (up) 165249 - 17pp
Keywords Gamma-ray; Position sensitive detectors; Monolithic crystals; Compton imaging; Machine Learning; Convolutional Neural Networks; Total Energy Detector; Neutron capture cross-section
Abstract We investigate five different models to reconstruct the 3D gamma-ray hit coordinates in five large LaCl3(Ce) monolithic crystals optically coupled to pixelated silicon photomultipliers. These scintillators have a base surface of 50 x 50 mm(2) and five different thicknesses, from 10 mm to 30 mm. Four of these models are analytical prescriptions and one is based on a Convolutional Neural Network. Average resolutions close to 1-2 mm fwhm are obtained in the transverse crystal plane for crystal thicknesses between 10 mm and 20 mm using analytical models. For thicker crystals average resolutions of about 3-5 mm fwhm are obtained. Depth of interaction resolutions between 1 mm and 4 mm are achieved depending on the distance of the interaction point to the photosensor surface. We propose a Machine Learning algorithm to correct for linearity distortions and pin-cushion effects. The latter allows one to keep a large field of view of about 70%-80% of the crystal surface, regardless of crystal thickness. This work is aimed at optimizing the performance of the so-called Total Energy Detector with Compton imaging capability (i-TED) for time-of-flight neutron capture cross-section measurements.
Address [Balibrea-Correa, J.; Lerendegui-Marco, J.; Babiano-Suarez, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros-Rodriguez, P.; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: javier.balibrea@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000641308300007 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4803
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Author Borys, D. et al; Brzezinski, K.
Title ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging Type Journal Article
Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 67 Issue 22 Pages (up) 224002 - 15pp
Keywords proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging
Abstract Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).
Address [Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000885248200001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5416
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Author Ros Garcia, A.; Barrio, J.; Etxebeste, A.; Garcia-Lopez, J.; Jimenez-Ramos, M.C.; Lacasta, C.; Muñoz, E.; Oliver, J.F.; Roser, J.; Llosa, G.
Title MACACO II test-beam with high energy photons Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue 24 Pages (up) 245027 - 12pp
Keywords Compton imaging; Compton camera; proton therapy; LaBr3; test-beam; image reconstruction
Abstract The IRIS group at IFIC Valencia is developing a three-layer Compton camera for treatment monitoring in proton therapy. The system is composed of three detector planes, each made of a LaBr3<i monolithic crystal coupled to a SiPM array. Having obtained successful results with the first prototype (MACACO) that demonstrated the feasibility of the proposed technology, a second prototype (MACACO II) with improved performance has been developed, and is the subject of this work. The new system has an enhanced detector energy resolution which translates into a higher spatial resolution of the telescope. The image reconstruction method has also been improved with an accurate model of the sensitivity matrix. The device has been tested with high energy photons at the National Accelerator Centre (CNA, Seville). The tests involved a proton beam of 18 MeV impinging on a graphite target, to produce 4.4 MeV photons. Data were taken at different system positions of the telescope with the first detector at 65 and 160 mm from the target, and at different beam intensities. The measurements allowed successful reconstruction of the photon emission distribution at two target positions separated by 5 mm in different telescope configurations. This result was obtained both with data recorded in the first and second telescope planes (two interaction events) and, for the first time in beam experiments, with data recorded in the three planes (three interaction events).
Address [Ros Garcia, A.; Barrio, J.; Etxebeste, A.; Lacasta, C.; Munoz, E.; Oliver, J. F.; Roser, J.; Llosa, G.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: arosgar@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000600803000001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4654
Permanent link to this record