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Garcilazo, H., Valcarce, A., & Vijande, J. (2016). Maximal isospin few-body systems of nucleons and Xi hyperons. Phys. Rev. C, 94(2), 024002–3pp.
Abstract: By using local central Yukawa-type interactions that reproduce the low-energy parameters of the latest updates of the Nijmegen ESC08c potentials, we show that the N Xi, NN Xi, N Xi Xi, and NN Xi Xi systems with maximal isospin are bound. Since in these states the strong decay N Xi -> Lambda Lambda is forbidden by isospin conservation, these strange few-body systems will be stable under the strong interaction. These results may suggest that other states with different number of Ns and Xi s in the maximal isospin channel could also be bound.
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Granero, D., Perez-Calatayud, J., Vijande, J., Ballester, F., & Rivard, M. J. (2014). Limitations of the TG-43 formalism for skin high-dose-rate brachytherapy dose calculations. Med. Phys., 41(2), 021703–8pp.
Abstract: Purpose: In skin high-dose-rate (HDR) brachytherapy, sources are located outside, in contact with, or implanted at some depth below the skin surface. Most treatment planning systems use the TG-43 formalism, which is based on single-source dose superposition within an infinite water medium without accounting for the true geometry in which conditions for scattered radiation are altered by the presence of air. The purpose of this study is to evaluate the dosimetric limitations of the TG-43 formalism in HDR skin brachytherapy and the potential clinical impact. Methods: Dose rate distributions of typical configurations used in skin brachytherapy were obtained: a 5 cm x 5 cm superficial mould; a source inside a catheter located at the skin surface with and without backscatter bolus; and a typical interstitial implant consisting of an HDR source in a catheter located at a depth of 0.5 cm. Commercially available HDR Co-60 and Ir-192 sources and a hypothetical Yb-169 source were considered. The Geant4Monte Carlo radiation transport code was used to estimate dose rate distributions for the configurations considered. These results were then compared to those obtained with the TG-43 dose calculation formalism. In particular, the influence of adding bolus material over the implant was studied. Results: For a 5 cm x 5 cm Ir-192 superficial mould and 0.5 cm prescription depth, dose differences in comparison to the TG-43 method were about -3%. When the source was positioned at the skin surface, dose differences were smaller than -1% for Co-60 and Ir-192, yet -3% for Yb-169. For the interstitial implant, dose differences at the skin surface were -7% for Co-60, -0.6% for Ir-192, and -2.5% for Yb-169. Conclusions: This study indicates the following: (i) for the superficial mould, no bolus is needed; (ii) when the source is in contact with the skin surface, no bolus is needed for either Co-60 and Ir-192. For lower energy radionuclides like Yb-169, bolus may be needed; and (iii) for the interstitial case, at least a 0.1 cm bolus is advised for Co-60 to avoid underdosing superficial target layers. For Ir-192 and Yb-169, no bolus is needed. For those cases where no bolus is needed, its use might be detrimental as the lack of radiation scatter may be beneficial to the patient, although the 2% tolerance for dose calculation accuracy recommended in the AAPM TG-56 report is not fulfilled.
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Vijande, J., Valcarce, A., & Richard, J. M. (2012). Stability of hexaquarks in the string limit of confinement. Phys. Rev. D, 85(1), 014019–6pp.
Abstract: The stability of systems containing six quarks or antiquarks is studied within a simple string model inspired by the strong-coupling regime of quantum chromodynamics and used previously for tetraquarks and pentaquarks. We discuss both six-quark (q(6)) and three-quark-three-antiquark (q(3)($) over bar (3)) states. The quarks are assumed to be distinguishable and thus not submitted to antisymmetrization. It is found that the ground state of (q(6)) is stable against dissociation into two isolated baryons. For the case of (q(3)($) over bar (3)), our results indicate the existence of a bound state very close to the threshold. The investigations are extended to (q(3)Q(3)) and (Q(3) ($) over bar (3)) systems with two different constituent masses, and their stability is discussed as a function of the mass ratio.
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Carames, T. F., Vijande, J., & Valcarce, A. (2019). Exotic bc(q)over-bar(q)over-bar four-quark states. Phys. Rev. D, 99(1), 014006–9pp.
Abstract: We carry out a systematic study of exotic QQ'(q) over bar(q) over bar four-quark states containing distinguishable heavy flavors, b and c. Different generic constituent models are explored in an attempt to extract general conclusions. The results are robust, predicting the same sets of quantum numbers as the best candidates to lodge bound states independently of the model used, the isoscalar J(P) = 0(+) and J(P) = 1(+) states. The first state would be strong and electromagnetic-interaction stable, while the second would decay electromagnetically to (B) over barD gamma. Isovector states are found to be unbound, preventing the existence of charged partners. The interest on exotic heavy-light tetraquarks with nonidentical heavy flavors comes reinforced by the recent estimation of the production rate of the isoscalar bc (u) over bar(d) over bar J(P) = 1(+) state, 2 orders of magnitude larger than that of the bb (u) over bar(d) over bar analogous state.
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Assam, I., Vijande, J., Ballester, F., Perez-Calatayud, J., Poppe, B., & Siebert, F. A. (2022). Evaluation of dosimetric effects of metallic artifact reduction and tissue assignment on Monte Carlo dose calculations for I-125 prostate implants. Med. Phys., 49, 6195–6208.
Abstract: Purpose Monte Carlo (MC) simulation studies, aimed at evaluating the magnitude of tissue heterogeneity in I-125 prostate permanent seed implant brachytherapy (BT), customarily use clinical post-implant CT images to generate a virtual representation of a realistic patient model (virtual patient model). Metallic artifact reduction (MAR) techniques and tissue assignment schemes (TAS) are implemented on the post-implant CT images to mollify metallic artifacts due to BT seeds and to assign tissue types to the voxels corresponding to the bright seed spots and streaking artifacts, respectively. The objective of this study is to assess the combined influence of MAR and TAS on MC absorbed dose calculations in post-implant CT-based phantoms. The virtual patient models used for I-125 prostate implant MC absorbed dose calculations in this study are derived from the CT images of an external radiotherapy prostate patient without BT seeds and prostatic calcifications, thus averting the need to implement MAR and TAS. Methods The geometry of the IsoSeed I25.S17plus source is validated by comparing the MC calculated results of the TG-43 parameters for the line source approximation with the TG-43U1S2 consensus data. Four MC absorbed dose calculations are performed in two virtual patient models using the egs_brachy MC code: (1) TG-43-based D-w,w-TG(43), (2) D-w,D-w-MBDC that accounts for interseed scattering and attenuation (ISA), (3) D-m,D-m that examines ISA and tissue heterogeneity by scoring absorbed dose in tissue, and (4) D-w,D-m that unlike D-m,D-m scores absorbed dose in water. The MC absorbed doses (1) and (2) are simulated in a TG-43 patient phantom derived by assigning the densities of every voxel to 1.00 g cm(-3) (water), whereas MC absorbed doses (3) and (4) are scored in the TG-186 patient phantom generated by mapping the mass density of each voxel to tissue according to a CT calibration curve. The MC absorbed doses calculated in this study are compared with VariSeed v8.0 calculated absorbed doses. To evaluate the dosimetric effect of MAR and TAS, the MC absorbed doses of this work (independent of MAR and TAS) are compared to the MC absorbed doses of different I-125 source models from previous studies that were calculated with different MC codes using post-implant CT-based phantoms generated by implementing MAR and TAS on post-implant CT images. Results The very good agreement of TG-43 parameters of this study and the published consensus data within 3% validates the geometry of the IsoSeed I25.S17plus source. For the clinical studies, the TG-43-based calculations show a D-90 overestimation of more than 4% compared to the more realistic MC methods due to ISA and tissue composition. The results of this work generally show few discrepancies with the post-implant CT-based dosimetry studies with respect to the D-90 absorbed dose metric parameter. These discrepancies are mainly Type B uncertainties due to the different I-125 source models and MC codes. Conclusions The implementation of MAR and TAS on post-implant CT images have no dosimetric effect on the I-125 prostate MC absorbed dose calculation in post-implant CT-based phantoms.
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