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Muñoz, E., Barrio, J., Etxebeste, A., Ortega, P. G., Lacasta, C., Oliver, J. F., et al. (2017). Performance evaluation of MACACO: a multilayer Compton camera. Phys. Med. Biol., 62(18), 7321–7341.
Abstract: Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm.
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Marco-Hernandez, R., Alves, D., Angoletta, M. E., Marqversen, O., Molendijk, J., Oponowicz, E., et al. (2017). The AD and ELENA orbit, trajectory and intensity measurement systems. J. Instrum., 12, P07024–24pp.
Abstract: This paper describes the new Antiproton Decelerator (AD) orbit measurement system and the Extra Low ENergy Antiproton ring (ELENA) orbit, trajectory and intensity measurement system. The AD machine at European Organization for Nuclear Research (CERN) is presently being used to decelerate antiprotons from 3.57 GeV/c to 100 MeV/c for matter vs anti-matter comparative studies. The ELENA machine, presently under commissioning, has been designed to provide an extra deceleration stage down to 13.7 MeV/c. The AD orbit system is based on 32 horizontal and 27 vertical electrostatic Beam Position Monitor (BPM) fitted with existing low noise front-end amplifiers while the ELENA system consists of 24 BPMs equipped with new low-noise head amplifiers. In both systems the front-end amplifiers generate a difference (delta) and a sum (sigma) signal which are sent to the digital acquisition system, placed tens of meters away from the AD or ELENA rings, where they are digitized and further processed. The beam position is calculated by dividing the difference signal by the sum signal either using directly the raw digitized data for measuring the turn-by-turn trajectory in the ELENA system or after down-mixing the signals to baseband for the orbit measurement in both machines. The digitized sigma signal will be used in the ELENA system to calculate the bunched beam intensity and the Schottky parameters with coasting beam after passing through different signal processing chain. The digital acquisition arrangement for both systems is based on the same hardware, also used in the ELENA Low Level Radio Frequency (LLRF) system, which follows the VME Switched Serial (VXS) enhancement of the Versa Module Eurocard 64x extension (VME64x) standard and includes VITA 57 standard Field Programmable Gate Array Mezzanine Card (FMC). The digital acquisition Field Programmable Gate Array (FPGA) andDigital Signal Processor (DSP) firmware sharesmany common functionalities with the LLRF system but has been tailored for this measurement application in particular. Specific control and acquisition software has been developed for these systems. Both systems are installed in AD and ELENA. The AD orbit system currently measures the orbit in AD while the ELENA system is being used in the commissioning of the ELENA ring.
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Poley, L. et al, & Lacasta, C. (2017). Investigations into the impact of locally modified sensor architectures on the detection efficiency of silicon micro-strip sensors. J. Instrum., 12, P07006–17pp.
Abstract: The High Luminosity Upgrade of the LHC will require the replacement of the Inner Detector of ATLAS with the Inner Tracker (ITk) in order to cope with higher radiation levels and higher track densities. Prototype silicon strip detector modules are currently developed and their performance is studied in both particle test beams and X-ray beams. In previous test beam measurements of prototype modules, the response of silicon sensors has been studied in detailed scans across individual sensor strips. These scans found instances of sensor strips collecting charge across areas on the sensor deviating from the geometrical width of a sensor strip. The variations have been linked to local features of the sensor architecture. This paper presents results of detailed sensor measurements in both X-ray and particle beams investigating the impact of sensor features (metal pads and p-stops) on the sensor strip response.
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Ma, Y. Z., Vijande, J., Ballester, F., Tedgren, A. C., Granero, D., Haworth, A., et al. (2017). A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy. Med. Phys., 44(11), 5961–5976.
Abstract: PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy.
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Kuehn, S. et al, Bernabeu, J., Lacasta, C., Marco-Hernandez, R., Santoyo, D., Solaz, C., et al. (2017). Prototyping of hybrids and modules for the forward silicon strip tracking detector for the ATLAS Phase-II upgrade. J. Instrum., 12, P05015–26pp.
Abstract: For the High-Luminosity upgrade of the Large Hadron Collider an increased instantaneous luminosity of up to 7.5 . 10(34) cm(-2) s(-1), leading to a total integrated luminosity of up to 3000 fb(-1), is foreseen. The current silicon and transition radiation tracking detectors of the ATLAS experiment will be unable to cope with the increased track densities and radiation levels, and will need to be replaced. The new tracking detector will consist entirely of silicon pixel and strip detectors. In this paper, results on the development and tests of prototype components for the new silicon strip detector in the forward regions (end-caps) of the ATLAS detector are presented. Flex-printed readout boards with fast readout chips, referred to as hybrids, and silicon detector modules are investigated. The modules consist of a hybrid glued onto a silicon strip sensor. The channels on both are connected via wire-bonds for readout and powering. Measurements of important performance parameters and a comparison of two possible readout schemes are presented. In addition, the assembly procedure is described and recommendations for further prototyping are derived.
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