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Balibrea-Correa, J., Lerendegui-Marco, J., Calvo, D., Caballero, L., Babiano, V., Ladarescu, I., et al. (2021). A first prototype of C6D6 total-energy detector with SiPM readout for neutron capture time-of-flight experiments. Nucl. Instrum. Methods Phys. Res. A, 985, 164709–8pp.
Abstract: Low efficiency total-energy detectors (TEDs) are one of the main tools for neutron capture cross section measurements utilizing the time-of-flight (TOF) technique. State-of-the-art TEDs are based on a C6D6 liquid-scintillation cell optically coupled to a fast photomultiplier tube. The large photomultiplier tube represents yet a significant contribution to the so-called neutron sensitivity background, which is one of the most conspicuous sources of uncertainty in this type of experiments. Here we report on the development of a first prototype of a TED based on a silicon-photomultiplier (SiPM) readout, thus resulting in a lightweight and much more compact detector. Apart from the envisaged improvement in neutron sensitivity, the new system uses low voltage (+28 V) and low current supply (-50 mA), which is more practical than the-kV supply required by conventional photomultipliers. One important difficulty hindering the earlier implementation of SiPM readout for this type of detector was the large capacitance for the output signal when all pixels of a SiPM array are summed together. The latter leads to long pulse rise and decay times, which are not suitable for time-of-flight experiments. In this work we demonstrate the feasibility of a Schottky-diode multiplexing readout approach, that allows one to preserve the excellent timing properties of SiPMs, hereby paving the way for their implementation in future neutron TOF experiments.
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Ballester, F., Granero, D., Perez-Calatayud, J., Venselaar, J. L. M., & Rivard, M. J. (2010). Study of encapsulated Tm-170 sources for their potential use in brachytherapy. Med. Phys., 37(4), 1629–1637.
Abstract: Methods: The authors have assumed a theoretical Tm-170 cylindrical source encapsulated with stainless steel and typical dimensions taken from the currently available HDR Ir-192 brachytherapy sources. The dose-rate distribution was calculated for this source using the GEANT4 Monte Carlo (MC) code considering both photon and electron Tm-170 spectra. The AAPM TG-43 U1 brachytherapy dosimetry parameters were derived. To study general properties of Tm-170 encapsulated sources, spherical sources encapsulated with stainless steel and platinum were also studied. Moreover, the influence of small variations in the active core and capsule dimensions on the dosimetric characteristics was assessed. Treatment times required for a Tm-170 source were compared to those for Ir-192 and Yb-169 for the same contained activity. Results: Due to the energetic beta spectrum and the large electron yield, the bremsstrahlung contribution to the dose was of the same order of magnitude as from the emitted gammas and characteristic x rays. Moreover, the electron spectrum contribution to the dose was significant up to 4 mm from the source center compared to the photon contribution. The dose-rate constant Lambda of the cylindrical source was 1.23 cGy h(-1) U-1. The behavior of the radial dose function showed promise for applications in brachytherapy. Due to the electron spectrum, the anisotropy was large for r < 6 mm. Variations in manufacturing tolerances did not significantly influence the final dosimetry data when expressed in cGy h(-1) U-1. For typical capsule dimensions, maximum reference dose rates of about 0.2, 10, and 2 Gy min(-1) would then be obtained for Tm-170, Ir-192, and Yb-169, respectively, resulting in treatment times greater than those for HDR Ir-192 brachytherapy. Conclusions: The dosimetric characteristics of source designs exploiting the low photon energy of Tm-170 were studied for potential application in HDR-brachytherapy. Dose-rate distributions were obtained for cylindrical and simplified spherical Tm-170 source designs (stainless steel and platinum capsule materials) using MC calculations. Despite the high activity of Tm-170, calculated treatment times were much longer than for Ir-192.
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Ballester, F., Tedgren, A. C., Granero, D., Haworth, A., Mourtada, F., Fonseca, G. P., et al. (2015). A generic high-dose rate Ir-192 brachytherapy source for evaluation of model-based dose calculations beyond the TG-43 formalism. Med. Phys., 42(6), 3048–3062.
Abstract: Purpose: In order to facilitate a smooth transition for brachytherapy dose calculations from the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) formalism to model-based dose calculation algorithms (MBDCAs), treatment planning systems (TPSs) using a MBDCA require a set of well-defined test case plans characterized by Monte Carlo (MC) methods. This also permits direct dose comparison to TG-43 reference data. Such test case plans should be made available for use in the software commissioning process performed by clinical end users. To this end, a hypothetical, generic high-dose rate (HDR) Ir-192 source and a virtual water phantom were designed, which can be imported into a TPS. Methods: A hypothetical, generic HDR Ir-192 source was designed based on commercially available sources as well as a virtual, cubic water phantom that can be imported into any TPS in DICOM format. The dose distribution of the generic Ir-192 source when placed at the center of the cubic phantom, and away from the center under altered scatter conditions, was evaluated using two commercial MBDCAs [Oncentra (R) Brachy with advanced collapsed-cone engine (ACE) and BrachyVision AcuRos (TM)]. Dose comparisons were performed using state-of-the-art MC codes for radiation transport, including ALGEBRA, BrachyDose, GEANT4, MCNP5, MCNP6, and pENELopE2008. The methodologies adhered to recommendations in the AAPM TG-229 report on high-energy brachytherapy source dosimetry. TG-43 dosimetry parameters, an along-away dose-rate table, and primary and scatter separated (PSS) data were obtained. The virtual water phantom of (201)(3) voxels (1 mm sides) was used to evaluate the calculated dose distributions. Two test case plans involving a single position of the generic HDR Ir-192 source in this phantom were prepared: (i) source centered in the phantom and (ii) source displaced 7 cm laterally from the center. Datasets were independently produced by different investigators. MC results were then compared against dose calculated using TG-43 and MBDCA methods. Results: TG-43 and PSS datasets were generated for the generic source, the PSS data for use with the ACE algorithm. The dose-rate constant values obtained from seven MC simulations, performed independently using different codes, were in excellent agreement, yielding an average of 1.1109 +/- 0.0004 cGy/(h U) (k = 1, Type A uncertainty). MC calculated dose-rate distributions for the two plans were also found to be in excellent agreement, with differences within type A uncertainties. Differences between commercial MBDCA and MC results were test, position, and calculation parameter dependent. On average, however, these differences were within 1% for ACUROS and 2% for ACE at clinically relevant distances. Conclusions: A hypothetical, generic HDR Ir-192 source was designed and implemented in two commercially available TPSs employing different MBDCAs. Reference dose distributions for this source were benchmarked and used for the evaluation of MBDCA calculations employing a virtual, cubic water phantom in the form of a CT DICOM image series. The implementation of a generic source of identical design in all TPSs using MBDCAs is an important step toward supporting univocal commissioning procedures and direct comparisons between TPSs.
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Bandos, I. A., de Azcarraga, J. A., & Meliveo, C. (2011). Extended supersymmetry in massless conformal higher spin theory. Nucl. Phys. B, 853(3), 760–776.
Abstract: We propose superfield equations in tensorial N-extended superspaces to describe the N = 2,4,8 supersymmetric generalizations of free conformal higher spin theories. These can be obtained by quantizing a superparticle model in N-extended tensorial superspace. The N-extended higher spin supermultiplets just contain scalar and 'spinor' fields in tensorial space so that, in contrast with the standard (super)space approach, no nontrivial generalizations of the Maxwell or Einstein equations to tensorial space appear when N > 2. For N = 4,8, the higher spin-tensorial components of the extended tensorial superfields are expressed through additional scalar and spinor fields in tensorial space which obey the same free higher spin equations, but that are axion-like in the sense that they possess Peccei-Quinn-like symmetries.
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Bandos, I. A., de Azcarraga, J. A., & Meliveo, C. (2012). Conformal higher spin theory in extended tensorial superspace. Fortschritte Phys.-Prog. Phys., 60(7-8), 861–867.
Abstract: We discuss the formulation of free conformal higher spin theories with extended N = 2, 4, 8 supersymmetry in N-extended tensorial superspaces. The superfield higher spin equations can be obtained by quantizing a superparticle model in N-extended tensorial superspace. The N-extended higher spin supermultiplets just contain scalar and spinor fields in tensorial space so that, in contrast with the standard (super)space approach, no nontrivial generalizations of the Maxwell or Einstein equations to tensorial space appear when N > 2. For N = 4, 8, the higher spin-tensorial components of the extended tensorial superfields are expressed through additional scalar and spinor fields in tensorial space which obey the same free higher spin equations, but that are axion-like in the sense that they possess Peccei-Quinn-like symmetries.
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Bandyopadhyay, P., Chun, E. J., Mandal, R., & Queiroz, F. S. (2019). Scrutinizing right-handed neutrino portal dark matter with Yukawa effect. Phys. Lett. B, 788, 530–534.
Abstract: Analyzing the neutrino Yukawa effect in the freeze-out process of a generic dark matter candidate with right-handed neutrino portal, we identify the parameter regions satisfying the observed dark matter relic density as well as the current Fermi-LAT and H.E.S.S. limits and the future CTA reach on gamma-ray signals. In this scenario the dark matter couples to the Higgs boson at one-loop level and thus could be detected by spin-independent nucleonic scattering for a reasonable range of the relevant parameters.
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Baran, J. et al, & Brzezinski, K. (2024). Feasibility of the J-PET to monitor the range of therapeutic proton beams. Phys. Medica, 118, 103301–9pp.
Abstract: Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application.
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Barducci, D., Bertuzzo, E., Caputo, A., & Hernandez, P. (2020). Minimal flavor violation in the see-saw portal. J. High Energy Phys., 06(6), 185–28pp.
Abstract: We consider an extension of the Standard Model with two singlet leptons, with masses in the electroweak range, that induce neutrino masses via the see-saw mechanism, plus a generic new physics sector at a higher scale, A. We apply the minimal flavor violation (MFV) principle to the corresponding Effective Field Theory (nu SMEFT) valid at energy scales E << A. We identify the irreducible sources of lepton flavor and lepton number violation at the renormalizable level, and apply the MFV ansatz to derive the scaling of the Wilson coefficients of the nu SMEFT operators up to dimension six. We highlight the most important phenomenological consequences of this hypothesis in the rates for exotic Higgs decays, the decay length of the heavy neutrinos, and their production modes at present and future colliders. We also comment on possible astrophysical implications.
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Barducci, D., Bertuzzo, E., Caputo, A., Hernandez, P., & Mele, B. (2021). The see-saw portal at future Higgs Factories. J. High Energy Phys., 03(3), 117–32pp.
Abstract: We consider an extension of the Standard Model with two right-handed singlet fermions with mass at the electroweak scale that induce neutrino masses, plus a generic new physics sector at a higher scale Lambda. We focus on the effective operators of lowest dimension d = 5, which induce new production and decay modes for the singlet fermions. We assess the sensitivity of future Higgs Factories, such as FCC-ee, CLIC-380, ILC and CEPC, to the coefficients of these operators for various center of mass energies. We show that future lepton colliders can test the cut-off of the theory up to Lambda similar or equal to 500-1000 TeV, surpassing the reach of future indirect measurements of the Higgs and Z boson widths. We also comment on the possibility of determining the underlying model flavor structure should a New Physics signal be observed, and on the impact of higher dimensional d = 6 operators on the experimental signatures.
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Barenboim, G. (2022). Some Aspects About Pushing the CPT and Lorentz Invariance Frontier With Neutrinos. Front. Physics, 10, 813753–7pp.
Abstract: The CPT symmetry, which combines Charge Conjugation, Parity, and Time Reversal, is a cornerstone of our model-building method, and its probable violation will endanger the most extended tool we presently utilize to explain physics, namely local relativistic quantum fields. However, the kaon system's conservation constraints appear to be rather severe. We will show in this paper that neutrino oscillation experiments can enhance this limit by many orders of magnitude, making them an excellent instrument for investigating the basis of our understanding of Nature. As a result, verifying CPT invariance does not evaluate a specific model, but rather the entire paradigm. Therefore, as the CPT's status in the neutrino sector, linked or not to Lorentz invariance violation, will be assessed at an unprecedented level by current and future long baseline experiments, distinguishing it from comparable experimental fingerprints coming from non-standard interactions is critical. Whether the entire paradigm or simply the conventional model of neutrinos is at jeopardy is significantly dependent on this.
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