Records |
Author |
Solevi, P.; Muñoz, E.; Solaz, C.; Trovato, M.; Dendooven, P.; Gillam, J.E.; Lacasta, C.; Oliver, J.F.; Rafecas, M.; Torres-Espallardo, I.; Llosa, G. |
Title |
Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams |
Type |
Journal Article |
Year |
2016 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume |
61 |
Issue |
14 |
Pages |
5149-5165 |
Keywords |
ion-beam therapy; range verification; prompt gamma; Compton camera; GATE |
Abstract |
In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery verification techniques are necessary to detect deviations from the planned treatment. Efforts are currently oriented towards the development of devices for real-time range monitoring. Among the different detector concepts proposed, Compton cameras are employed to detect prompt gammas and represent a valid candidate for real-time range verification. We present the first on-beam test of MACACO, a Compton telescope (multi-layer Compton camera) based on lanthanum bromide crystals and silicon photo-multipliers. The Compton telescope was first characterized through measurements and Monte Carlo simulations. The detector linearity was measured employing Na-22 and Am-Be sources, obtaining about 10% deviation from linearity at 3.44 MeV. A spectral image reconstruction algorithm was tested on synthetic data. Point-like sources emitting gamma rays with energy between 2 and 7 MeV were reconstructed with 3-5 mm resolution. The two-layer Compton telescope was employed to measure radiation emitted from a beam of 150 MeV protons impinging on a cylindrical PMMA target. Bragg-peak shifts were achieved via adjustment of the PMMA target location and the resulting measurements used during image reconstruction. Reconstructed Bragg peak profiles proved sufficient to observe peak-location differences within 10 mm demonstrating the potential of the MACACO Compton Telescope as a monitoring device for ion-beam therapy. |
Address |
[Solevi, Paola; Munoz, Enrique; Solaz, Carles; Trovato, Marco; Gillam, John E.; Lacasta, Carlos; Oliver, Josep F.; Rafecas, Magdalena; Torres-Espallardo, Irene; Llosa, Gabriela] IFIC CSIC UVEG, Inst Fis Corpuscular, Valencia, Spain, Email: paola.solevi@ovgu.de |
Corporate Author |
|
Thesis |
|
Publisher |
Iop Publishing Ltd |
Place of Publication |
|
Editor |
|
Language |
English |
Summary Language |
|
Original Title |
|
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
0031-9155 |
ISBN |
|
Medium |
|
Area |
|
Expedition |
|
Conference |
|
Notes |
WOS:000379555300007 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
2754 |
Permanent link to this record |
|
|
|
Author |
Llosa, G.; Trovato, M.; Barrio, J.; Etxebeste, A.; Muñoz, E.; Lacasta, C.; Oliver, J.F.; Rafecas, M.; Solaz, C.; Solevi, P. |
Title |
First Images of a Three-layer compton Telescope prototype for Treatment Monitoring in hadron Therapy |
Type |
Journal Article |
Year |
2016 |
Publication |
Frontiers in Oncology |
Abbreviated Journal |
Front. Oncol. |
Volume |
6 |
Issue |
|
Pages |
14 - 6pp |
Keywords |
Compton camera; Compton telescope; hadron therapy; treatment monitoring; LaBr3 |
Abstract |
A Compton telescope for dose monitoring in hadron therapy is under development at IFIC. The system consists of three layers of LaBr3 crystals coupled to silicon photomulti-plier arrays. Na-22 sources have been successfully imaged reconstructing the data with an ML-EM code. Calibration and temperature stabilization are necessary for the prototype operation at low coincidence rates. A spatial resolution of 7.8 mm FWHM has been obtained in the first imaging tests. |
Address |
[Llosa, Gabriela; Trovato, Marco; Barrio, John; Etxebeste, Ane; Munoz, Enrique; Lacasta, Carlos; Oliver, Josep F.; Rafecas, Magdalena; Solaz, Carles; Solevi, Paola] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: gabriela.llosa@ific.uv.es |
Corporate Author |
|
Thesis |
|
Publisher |
Frontiers Media Sa |
Place of Publication |
|
Editor |
|
Language |
English |
Summary Language |
|
Original Title |
|
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
Series Volume |
|
Series Issue |
|
Edition |
|
ISSN |
2234-943x |
ISBN |
|
Medium |
|
Area |
|
Expedition |
|
Conference |
|
Notes |
WOS:000369799800001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ elepoucu @ |
Serial |
2785 |
Permanent link to this record |