Abstract: We perform a general model-independent analysis of b -> c tau(nu) over bar (tau) transitions, including measurements of R-D, R-D*, their q(2) differential distributions, the recently measured longitudinal D* polarization F-L(D)*, and constraints from the B-c -> tau(nu) over bar (tau) lifetime, each of which has significant impact on the fit. A global fit to a general set of Wilson coefficients of an effective low-energy Hamiltonian is presented, the solutions of which are interpreted in terms of hypothetical new-physics mediators. From the obtained results we predict selected b -> c tau(nu) over bar (tau) observables, such as the baryonic transition Lambda(b) -> Lambda(c)tau(nu) over bar (tau), the ratio R-J/psi, the forward-backward asymmetries A(FB)(D()*()), the tau polarization asymmetries P-tau(D()*()), and the longitudinal D* polarization fraction F-L(D)*. The latter shows presently a slight tension with any new-physics model, such that an improved measurement could have an important impact. We also discuss the potential change due the very recently announced preliminary R-D(*) measurement by the Belle collaboration.

Abstract: The applicability extent of hadron therapy for tumor treatment is currently limited by the lack of reliable online monitoring techniques. An active topic of investigation is the research of monitoring systems based on the detection of secondary radiation produced during treatment. MACACO, a multi-layer Compton camera based on LaBr3 scintillator crystals and SiPMs, is being developed at IFIC-Valencia for this purpose. This work reports the results obtained from measurements of a 150 MeV proton beam impinging on a PMMA target. A neural network trained on Monte Carlo simulations is used for event selection, increasing the signal to background ratio before image reconstruction. Images of the measured prompt gamma distributions are reconstructed by means of a spectral reconstruction code, through which the 4.439 MeV spectral line is resolved. Images of the emission distribution at this energy are reconstructed, allowing calculation of the distal fall-off and identification of target displacements of 3 mm.

Abstract: Given the strong variations in the sensitivity of Compton cameras for the detection of events originating from different points in the field of view (FoV), sensitivity correction is often necessary in Compton image reconstruction. Several approaches for the calculation of the sensitivity matrix have been proposed in the literature. While most of these models are easily implemented and can be useful in many cases, they usually assume high angular coverage over the scattered photon, which is not the case for our prototype. In this work, we have derived an analytical model that allows us to calculate a detailed sensitivity matrix, which has been compared to other sensitivity models in the literature. Specifically, the proposed model describes the probability of measuring a useful event in a two-plane Compton camera, including the most relevant physical processes involved. The model has been used to obtain an expression for the system and sensitivity matrices for iterative image reconstruction. These matrices have been validated taking Monte Carlo simulations as a reference. In order to study the impact of the sensitivity, images reconstructed with our sensitivity model and with other models have been compared. Images have been reconstructed from several simulated sources, including point-like sources and extended distributions of activity, and also from experimental data measured with Na-22 sources. Results show that our sensitivity model is the best suited for our prototype. Although other models in the literature perform successfully in many scenarios, they are not applicable in all the geometrical configurations of interest for our system. In general, our model allows to effectively recover the intensity of point-like sources at different positions in the FoV and to reconstruct regions of homogeneous activity with minimal variance. Moreover, it can be employed for all Compton camera configurations, including those with low angular coverage over the scatterer.

Abstract: One factor limiting the current applicability extent of hadron therapy is the lack of a reliable method for real time treatment monitoring. The use of Compton imaging systems as monitors requires the correct reconstruction of the distribution of prompt gamma productions during patient irradiation. In order to extract the maximum information from all the measurable events, we implemented a spectral reconstruction method that assigns to all events a probability of being either partial or total energy depositions. The method, implemented in a list-mode maximum likelihood expectation maximization algorithm, generates a four dimensional image in the joint spatial-spectral domain, in which the voxels containing the emission positions and energies are obtained. The analytical model used for the system response function is also employed to derive an analytical expression for the sensitivity, which is calculated via Monte Carlo integration. The performance of the method is evaluated through reconstruction of various experimental and simulated sources with different spatial and energy distributions. The results show that the proposed method can recover the spectral and spatial information simultaneously, but only under the assumption of ideal measurements. The analysis of the Monte Carlo simulations has led to the identification of two important degradation sources: the mispositioning of the gamma interaction point and the missing energy recorded in the interaction. Both factors are related to the high energy transferred to the recoil electrons, which can travel far from the interaction point and even escape the detector. These effects prevent the direct application of the current method in more realistic scenarios. Nevertheless, experimental point-like sources have been accurately reconstructed and the spatial distributions and spectral emission of complex simulated phantoms can be identified.

Abstract: The impact of dark matter-neutrino interactions on the measurement of the cosmological parameters has been investigated in the past in the context of massless neutrinos exclusively. Here we revisit the role of a neutrino-dark matter coupling in light of ongoing cosmological tensions by implementing the full Boltzmann hierarchy for three massive neutrinos. Our tightest 95% CL upper limit on the strength of the interactions, parameterized via u(chi) = sigma(0)/sigma(Th) (m(chi)/100GeV)(-1), is u(chi) <= 3.34 . 10(-4), arising from a combination of Planck TTTEEE data, Planck lensing data and SDSS BAO data. This upper bound is, as expected, slightly higher than previous results for interacting massless neutrinos, due to the correction factor associated with neutrino masses. We find that these interactions significantly relax the lower bounds on the value of sigma 8 that is inferred in the context of Lambda CDM from the Planck data, leading to agreement within 1-2 sigma with weak lensing estimates of sigma 8, as those from KiDS1000. However, the presence of these interactions barely affects the value of the Hubble constant H-0.