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Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J. |
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Title |
Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source |
Type |
Journal Article |
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Year |
2024 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
14 |
Issue |
1 |
Pages |
11448 - 12pp |
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Abstract |
Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range. |
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Address |
[Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es |
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Nature Portfolio |
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English |
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2045-2322 |
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Notes |
WOS:001228252900017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
6143 |
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Author |
Oliver, S.; Rodriguez Bosca, S.; Gimenez-Alventosa, V. |
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Title |
Enabling particle transport on CAD-based geometries for radiation simulations with penRed |
Type |
Journal Article |
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Year |
2024 |
Publication |
Computer Physics Communications |
Abbreviated Journal |
Comput. Phys. Commun. |
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Volume |
298 |
Issue |
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Pages |
109091 - 11pp |
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Keywords |
Radiation transport; PENELOPE physics; Monte Carlo simulation; PenRed; CAD; Triangular surface mesh |
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Abstract |
Geometry construction is a fundamental aspect of any radiation transport simulation, regardless of the Monte Carlo code being used. Typically, this process is tedious, time-consuming, and error-prone. The conventional approach involves defining geometries using mathematical objects or surfaces. However, this method comes with several limitations, especially when dealing with complex models, particularly those with organic shapes. Furthermore, since each code employs its own format and methodology for defining geometries, sharing and reproducing simulations among researchers becomes a challenging task. Consequently, many codes have implemented support for simulating over geometries constructed via Computer-Aided Design (CAD) tools. Unfortunately, this feature is lacking in penRed and other PENELOPE physics-based codes. Therefore, the objective of this work is to implement such support within the penRed framework. New version program summary Program Title: Parallel Engine for Radiation Energy Deposition (penRed) CPC Library link to program files: https://doi.org/10.17632/rkw6tvtngy.2 Developer's repository link: https://github.com/PenRed/PenRed Code Ocean capsule: https://codeocean.com/capsule/1041417/tree Licensing provisions: GNU Affero General Public License v3 Programming language: C++ standard 2011. Journal reference of previous version: V. Gimenez-Alventosa, V. Gimenez Gomez, S. Oliver, PenRed: An extensible and parallel Monte-Carlo framework for radiation transport based on PENELOPE, Computer Physics Communications 267 (2021) 108065. doi:https://doi.org/10.1016/j.cpc.2021.108065. Does the new version supersede the previous version?: Yes Reasons for the new version: Implements the capability to simulate on CAD constructed geometries, among many other features and fixes. Summary of revisions: All changes applied through the code versions are summarized in the file CHANGELOG.md in the repository package. Nature of problem: While Monte Carlo codes have proven valuable in simulating complex radiation scenarios, they rely heavily on accurate geometrical representations. In the same way as many other Monte Carlo codes, penRed employs simple geometric quadric surfaces like planes, spheres and cylinders to define geometries. However, since these geometric models offer a certain level of flexibility, these representations have limitations when it comes to simulating highly intricate and irregular shapes. Anatomic structures, for example, require detailed representations of organs, tissues and bones, which are difficult to achieve using basic geometric objects. Similarly, complex devices or intricate mechanical systems may have designs that cannot be accurately represented within the constraints of such geometric models. Moreover, when the complexity of the model increases, geometry construction process becomes more difficult, tedious, time-consuming and error-prone [2]. Also, as each Monte Carlo geometry library uses its own format and construction method, reproducing the same geometry among different codes is a challenging task. Solution method: To face the problems stated above, the objective of this work is to implement the capability to simulate using irregular and adaptable meshed geometries in the penRed framework. This kind of meshes can be constructed using Computer-Aided Design (CAD) tools, the use of which is very widespread and streamline the design process. This feature has been implemented in a new geometry module named “MESH_BODY” specific for this kind of geometries. This one is freely available and usable within the official penRed package1. It can be used since penRed version 1.9.3b and above. |
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Address |
[Oliver, S.] Univ Politecn Valencia, Inst Seguridad Ind Radiofis & Medioambiental ISIRY, Cami Vera S-N, Valencia 46022, Spain |
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Elsevier |
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English |
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ISSN |
0010-4655 |
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Notes |
WOS:001172840800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6077 |
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Author |
n_TOF Collaboration (Amaducci, S. et al); Babiano-Suarez, V.; Caballero-Ontanaya, L.; Domingo-Pardo, C.; Ladarescu, I.; Tain, J.L.; Tarifeño-Saldivia, A. |
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Title |
Measurement of the 140Ceðn;γþ Cross Section at n_TOF and Its Astrophysical Implications for the Chemical Evolution of the Universe |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
132 |
Issue |
12 |
Pages |
122701 - 8pp |
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Keywords |
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Abstract |
140Ce(n, gamma) is a key reaction for slow neutron -capture (s -process) nucleosynthesis due to being a bottleneck in the reaction flow. For this reason, it was measured with high accuracy (uncertainty approximate to 5%) at the n_TOF facility, with an unprecedented combination of a high purity sample and low neutron -sensitivity detectors. The measured Maxwellian averaged cross section is up to 40% higher than previously accepted values. Stellar model calculations indicate a reduction around 20% of the s -process contribution to the Galactic cerium abundance and smaller sizeable differences for most of the heavier elements. No variations are found in the nucleosynthesis from massive stars. |
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Address |
[Amaducci, S.; Cosentino, L.; Finocchiaro, P.; Brown, A.] INFN, Lab Nazl Sud, Catania, Italy |
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Amer Physical Soc |
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English |
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ISSN |
0031-9007 |
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Notes |
WOS:001202102900011 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6074 |
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Author |
Nieves, J.; Feijoo, A.; Albaladejo, M.; Du, M.L. |
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Title |
Lowest-lying 1/2- and 3/2- ΛQ resonances: From the strange to the bottom sectors |
Type |
Journal Article |
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Year |
2024 |
Publication |
Progress in Particle and Nuclear Physics |
Abbreviated Journal |
Prog. Part. Nucl. Phys. |
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Volume |
137 |
Issue |
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Pages |
104118 - 23pp |
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Keywords |
Heavy quark symmetry; Constituent quark-model; Molecule; Charmed; Bottomed |
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Abstract |
We present a detailed study of the lowest-lying 1/2(-) and 3/2(-) Lambda Q resonances both in the heavy 2 2 quark (bottom and charm) and the strange sectors. We have paid special attention to the interplay between the constituent quark-model and chiral baryon-meson degrees of freedom, which are coupled using a unitarized scheme consistent with leading-order heavy quark symmetries. We show that the Lambda(b)(5912) [J(P) = 1/2(-)], Lambda(b)(5920) [J(P) = 3/2(-)] and the Lambda(c)(2625) [J(P) = 3/2-], and the Lambda(1520) [J(P) = 3/2(-)] admitting larger breaking corrections, are heavyquark spin-flavor siblings. They can be seen as dressed quark-model states with Sigma Q(()*()) pi molecular components of the order of 30%. The J(P)=1(-) Lambda(2595) has, however, a higher molecular 2 probability of at least 50%, and even values greater than 70% can be easily accommodated. This is because it is located almost on top of the threshold of the Sigma(c)pi pair, which largely influences its properties. Although the light degrees of freedom in this resonance would be coupled to spin-parity 1(-) as in the Lambda(b)(5912), Lambda(b)(5920) and Lambda(c)(2625), the Lambda(c)(2595) should not be considered as a heavy-quark spin-flavor partner of the former ones. We also show that the Lambda(1405) chiral two-pole pattern does not have analogs in the 1 – charmed and bottomed sectors, because the 2 N D-(*()) and N (B) over bar (()*()) channels do not play for heavy quarks the decisive role that the N (K) over bar does in the strange sector, and the notable influence of the bare quark-model states for the charm and bottom resonances. Finally, we predict the existence of two Lambda(b)(6070) and two Lambda(c)(2765) heavy-quark spin and flavor sibling odd parity states. |
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Address |
[Nieves, J.; Feijoo, A.; Albaladejo, M.] Inst Fis Corpuscular, Ctr Mixto, CSIC UV, Valencia, Spain, Email: jmnieves@ific.uv.es; |
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Elsevier |
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English |
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Series Issue |
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Edition |
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ISSN |
0146-6410 |
ISBN |
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Expedition |
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Notes |
WOS:001243410100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6153 |
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Author |
NEXT Collaboration (Mistry, K. et al); Carcel, S.; Lopez-March, N.; Martin-Albo, J.; Novella, P.; Querol, M.; Romo-Luque, C.; Sorel, M.; Soto-Oton, J.; Uson, A. |
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Title |
Design, characterization and installation of the NEXT-100 cathode and electroluminescence regions |
Type |
Journal Article |
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Year |
2024 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
19 |
Issue |
2 |
Pages |
P02007 - 36pp |
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Keywords |
Detector design and construction technologies and materials; Double-beta decay detectors; Charge transport; multiplication and electroluminescence in rare gases and liquids; Time projection Chambers (TPC) |
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Abstract |
NEXT -100 is currently being constructed at the Laboratorio Subterraneo de Canfranc in the Spanish Pyrenees and will search for neutrinoless double beta decay using a high-pressure gaseous time projection chamber (TPC) with 100 kg of xenon. Charge amplification is carried out via electroluminescence (EL) which is the process of accelerating electrons in a high electric field region causing secondary scintillation of the medium proportional to the initial charge. The NEXT -100 EL and cathode regions are made from tensioned hexagonal meshes of 1 m diameter. This paper describes the design, characterization, and installation of these parts for NEXT -100. Simulations of the electric field are performed to model the drift and amplification of ionization electrons produced in the detector under various EL region alignments and rotations. Measurements of the electrostatic breakdown voltage in air characterize performance under high voltage conditions and identify breakdown points. The electrostatic deflection of the mesh is quantified and fit to a first -pr inciples mechanical model. Measurements were performed with both a standalone test EL region and with the NEXT-100 EL region before its installation in the detector. Finally, we describe the parts as installed in NEXT-100, following their deployment in Summer 2023. |
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Address |
[Mistry, K.; Jones, B. J. P.; Munson, B.; Norman, L.; Oliver, D.; Pingulkar, S.; Rodriguez-Tiscareno, M.; Silva, K.; Stogsdill, K.; Byrnes, N.; Dey, E.; Navarro, K. E.; Nygren, D. R.; Parmaksiz, I.] Univ Texas Arlington, Dept Phys, Arlington, TX 76019 USA, Email: next-src@pegaso.ific.uv.es |
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Publisher |
IOP Publishing Ltd |
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English |
Summary Language |
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ISSN |
1748-0221 |
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Conference |
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Notes |
WOS:001185791500003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6071 |
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Author |
NEXT Collaboration (Haefner, J. et al); Carcel, S.; Carrion, J.V.; Lopez-March, N.; Martin-Albo, J.; Muñoz Vidal, J.; Novella, P.; Querol, M.; Romo-Luque, C.; Sorel, M.; Soto-Oton, J.; Uson, A. |
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Title |
Demonstration of event position reconstruction based on diffusion in the NEXT-white detector |
Type |
Journal Article |
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Year |
2024 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
84 |
Issue |
5 |
Pages |
518 - 13pp |
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Keywords |
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Abstract |
Noble element time projection chambers are a leading technology for rare event detection in physics, such as for dark matter and neutrinoless double beta decay searches. Time projection chambers typically assign event position in the drift direction using the relative timing of prompt scintillation and delayed charge collection signals, allowing for reconstruction of an absolute position in the drift direction. In this paper, alternate methods for assigning event drift distance via quantification of electron diffusion in a pure high pressure xenon gas time projection chamber are explored. Data from the NEXT-White detector demonstrate the ability to achieve good position assignment accuracy for both high- and low-energy events. Using point-like energy deposits from Kr-83m calibration electron captures (E similar to 45 keV), the position of origin of low-energy events is determined to 2 cm precision with bias <1 mm. A convolutional neural network approach is then used to quantify diffusion for longer tracks (E >= 1.5 MeV), from radiogenic electrons, yielding a precision of 3 cm on the event barycenter. The precision achieved with these methods indicates the feasibility energy calibrations of better than 1% FWHM at Q(beta beta) in pure xenon, as well as the potential for event fiducialization in large future detectors using an alternate method that does not rely on primary scintillation. |
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Address |
[Haefner, J.; Contreras, T.] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA, Email: karen.navarro@uta.edu |
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Publisher |
Springer |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6044 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001228898800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6138 |
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Author |
Navarro, P.; Gimeno, B.; Monzo-Cabrera, J.; Diaz-Morcillo, A.; Blas, D. |
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Title |
Study of a cubic cavity resonator for gravitational waves detection in the microwave frequency range |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
10 |
Pages |
104048 - 19pp |
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Keywords |
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Abstract |
The direct detection of gravitational waves (GWs) of frequencies above MHz has recently received considerable attention. In this work, we present a precise study of the reach of a cubic cavity resonator to GWs in the microwave range, using for the first time tools allowing to perform realistic simulations. Concretely, the boundary integral -resonant mode expansion (BI-RME) 3D method, which allows us to obtain not only the detected power but also the detected voltage (magnitude and phase), is used here. After analyzing three cubic cavities for different frequencies and working simultaneously with three different degenerate modes at each cavity, we conclude that the sensitivity of the experiment is strongly dependent on the polarization and incidence angle of the GW. The presented experiment can reach sensitivities up to 1 x 10 – 19 at 100 MHz, 2 x 10 – 20 at 1 GHz, and 6 x 10 – 19 at 10 GHz for optimal angles and polarizations, and where in all cases we assumed an integration time of Delta t 1 / 4 1 ms. These results provide a strong case for further developing the use of cavities to detect GWs. Moreover, the possibility of analyzing the detected voltage (magnitude and phase) opens a new interferometric detection scheme based on the combination of the detected signals from multiple cavities. |
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Address |
[Navarro, Pablo; Monzo-Cabrera, Juan; Diaz-Morcillo, Alejandro] Univ Politecn Cartagena, Dept Tecnol Informac & Comunicac, Plaza Hosp 1, Cartagena 30302, Spain, Email: pablonm.ct.94@gmail.com; |
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Publisher |
Amer Physical Soc |
Place of Publication |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2470-0010 |
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Notes |
WOS:001239272400007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
6152 |
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Author |
Nascimento, J.R.; Olmo, G.J.; Petrov, A.Y.; Porfirio, P.J. |
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Title |
On metric-affine bumblebee model coupled to scalar matter |
Type |
Journal Article |
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Year |
2024 |
Publication |
Nuclear Physics B |
Abbreviated Journal |
Nucl. Phys. B |
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Volume |
1004 |
Issue |
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Pages |
116577 - 10pp |
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Keywords |
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Abstract |
We consider the coupling of the metric-affine bumblebee gravity model to scalar matter and calculate the lower -order contributions to two -point functions of bumblebee and scalar fields in the weak gravity approximation. We also obtain the one -loop effective potentials for both scalar and vector fields. |
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Address |
[Nascimento, J. R.; Petrov, A. Yu.; Porfirio, P. J.] Univ Fed Paraiba, Dept Fis, Caixa Postal 5008, BR-58051970 Joao Pessoa, PB, Brazil, Email: jroberto@fisica.ufpb.br; |
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Publisher |
Elsevier |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
0550-3213 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001248177100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6157 |
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Author |
Nacher, E.; Briz, J.A.; Nerio, A.N.; Perea, A.; Tavora, V.G.; Tengblad, O.; Ciemala, M.; Cieplicka-Orynczak, N.; Maj, A.; Mazurek, K.; Olko, P.; Zieblinski, M.; Borge, M.J.G. |
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Title |
Characterization of a novel proton-CT scanner based on Silicon and LaBr3(Ce) detectors |
Type |
Journal Article |
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Year |
2024 |
Publication |
European Physical Journal Plus |
Abbreviated Journal |
Eur. Phys. J. Plus |
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Volume |
139 |
Issue |
5 |
Pages |
404 - 9pp |
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Keywords |
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Abstract |
Treatment planning systems at proton-therapy centres entirely use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body, as derived from X-ray images, suffer from important proton-range uncertainties. In order to reduce this uncertainty in range, one could use proton-CT images instead. The main goal of this work is to test the capabilities of a newly-developed proton-CT scanner, based on the use of a set of tracking detectors and a high energy resolution scintillator for the residual energy of the protons. Different custom-made phantoms were positioned at the field of view of the scanner and were irradiated with protons at the CCB proton-therapy center in Krakow. We measured with the phantoms at different angles and produced sinograms that were used to obtain reconstructed images by Filtered Back-Projection. The obtained images were used to determine the capabilities of our scanner in terms of spatial resolution and proton Relative Stopping Power (RSP) mapping and validate its use as proton-CT scanner. The results show that the scanner can produce medium-high quality images, with spatial resolution better than 2 mm in radiography, below 3 mm in tomography and resolving power in the RSP comparable to other state-of-the-art pCT scanners. |
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Address |
[Nacher, E.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia 46980, Spain, Email: enrique.nacher@csic.es |
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Springer Heidelberg |
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English |
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ISSN |
2190-5444 |
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Notes |
WOS:001218502700005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6123 |
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Author |
NA64 Collaboration (Andreev, Y.M. et al); Molina Bueno, L.; Tuzi, M. |
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Title |
First Results in the Search for Dark Sectors at NA64 with the CERN SPS High Energy Muon Beam |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
132 |
Issue |
21 |
Pages |
211803 - 7pp |
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Abstract |
We report the first search for dark sectors performed at the NA64 experiment employing a high energy muon beam and a missing energy-momentum technique. Muons from the M2 beamline at the CERN Super Proton Synchrotron with a momentum of 160 GeV/c are directed to an active target. The signal signature consists of a single scattered muon with momentum < 80 GeV/c in the final state, accompanied by missing energy, i.e., no detectable activity in the downstream calorimeters. For a total dataset of (1.98 +/- 0.02) x 10(10) muons on target, no event is observed in the expected signal region. This allows us to set new limits on the remaining (m(Z)'; g(Z)') parameter space of a new Z' (L-mu – L-tau) vector boson which could explain the muon (g – 2)(mu) anomaly. Additionally, our study excludes part of the parameter space suggested by the thermal dark matter relic abundance. Our results pave the way to explore dark sectors and light dark matter with muon beams in a unique and complementary way to other experiments. |
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Address |
[Banerjee, D.; Bernhard, J.; Charitonidis, N.; Girod, S.] CERN, European Org Nucl Res, CH-1211 Geneva, Switzerland, Email: paolo.crivelli@cern.ch; |
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Publisher |
Amer Physical Soc |
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English |
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ISSN |
0031-9007 |
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Notes |
WOS:001239696000003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6142 |
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| Permanent link to this record |
