Abstract: The full optimization of the design and operation of instruments whose functioning relies on the interaction of radiation with matter is a super-human task, due to the large dimensionality of the space of possible choices for geometry, detection technology, materials, data-acquisition, and information-extraction techniques, and the interdependence of the related parameters. On the other hand, massive potential gains in performance over standard, “experience-driven” layouts are in principle within our reach if an objective function fully aligned with the final goals of the instrument is maximized through a systematic search of the configuration space. The stochastic nature of the involved quantum processes make the modeling of these systems an intractable problem from a classical statistics point of view, yet the construction of a fully differentiable pipeline and the use of deep learning techniques may allow the simultaneous optimization of all design parameters.

Abstract: We study the weak decay of the Lambda(b) into J/psi K Xi. and J/psi eta Lambda states, and relate these processes to the Lambda(b) -> J/psi(K) over barN decay mode. The elementary weak transition at the quark level proceeds via the creation of a J/psi meson and an excited sud system with I = 0, which upon hadronization leads to (K) over barN or eta Lambda pairs. These states undergo final-state interaction in coupled channels and produce a final meson-baryon pair. The K. state only occurs via rescattering, hence making the Lambda(b) -> J/psi K Xi process very sensitive to the details of the meson-baryon interaction in strangeness S = -1 and isospin I = 0. We show that the corresponding invariant mass distribution is dominated by the next-to-leading-order terms of the chiral interaction. The I = 0 selectivity of this decay, and its large sensitivity to the higher-order terms, makes its measurement very useful and complementary to the K- p -> K Xi cross section data. The rates of the Lambda(b) -> J/psi K Xi and Lambda(b) -> J/psi eta Lambda invariant mass distributions are sizable compared to those of the Lambda(b) -> J/psi(K) over barN decay, which is measured experimentally, and thus, we provide arguments for an experimental determination of these decay modes that will help us understand better the chiral dynamics at higher energies.

Abstract: We review lattice results related to pion, kaon, D-meson, B-meson, and nucleon physics with the aim of making them easily accessible to the nuclear and particle physics communities. More specifically, we report on the determination of the light-quark masses, the form factor f(+) (0) arising in the semileptonic K -> pi transition at zero momentum transfer, as well as the decay constant ratio Alf, and its consequences for the CKM matrix elements V-us and V-ud. Furthermore, we describe the results obtained on the lattice for some of the low-energy constants of SU(2)(L) x SU(2)(R) and SU(3)(L) x SU(3)(R) Chiral Perturbation Theory. We review the determination of the B-K parameter of neutral kaon mixing as well as the additional four B parameters that arise in theories of physics beyond the Standard Model. For the heavy-quark sector, we provide results for m(c) and m(b) as well as those for the decay constants, form factors, and mixing parameters of charmed and bottom mesons and baryons. These are the heavy-quark quantities most relevant for the determination of CKM matrix elements and the global CKM unitarity-triangle fit. We review the status of lattice determinations of the strong coupling constant alpha(s). We consider nucleon matrix elements, and review the determinations of the axial, scalar and tensor bilinears, both isovector and flavor diagonal. Finally, in this review we have added a new section reviewing determinations of scale-setting quantities.