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Verdu-Andres, S., Amaldi, U., & Faus-Golfe, A. (2013). CABOTO, a high-gradient linac for hadrontherapy. J. Radiat. Res., 54, 155–161.
Abstract: The field of hadrontherapy has grown rapidly in recent years. At present the therapeutic beam is provided by a cyclotron or a synchrotron, but neither cyclotrons nor synchrotrons present the best performances for hadrontherapy. The new generation of accelerators for hadrontherapy should allow fast active energy modulation and have a high repetition rate, so that moving organs can be appropriately treated in a reasonable time. In addition, a reduction of the dimensions and cost of the accelerators for hadrontherapy would make the acquisition and operation of a hadrontherapy facility more affordable, which would translate into great benefits for the potential hadrontherapy patients. The 'cyclinac', an accelerator concept that combines a cyclotron with a high-frequency linear accelerator (linac), is a fast-cycling machine specifically conceived to allow for fast active energy modulation. The present paper focuses on CABOTO (CArbon BOoster for Therapy in Oncology), a compact, efficient high-frequency linac that can accelerate C6+ ions and H-2 molecules from 150-410 MeV/u in similar to 24 m. The paper presents the latest design of CABOTO and discusses its performances.
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Verdera, A., Torres-Sanchez, P., Praena, J., & Porras, I. (2024). Study of the out-of-field dose from an accelerator-based neutron source for boron neutron capture therapy. Appl. Radiat. Isot., 212, 111458–6pp.
Abstract: One important issue in Boron Neutron Capture Therapy is the delivered dose to the tissues outside the tumor. An international standard for light ion beam systems sets two recommended limits for out-of-field dose based on distance from the field edge: maximum absorbed dose from all radiation types shall not exceed 0.5 % of the maximum dose at distances 15 cm to 50 cm from the field edge. At distances > 50 cm from the field edge, the maximum absorbed dose shall not exceed 0.1 %. This paper is a continuation of our previous works focused on the design of an accelerator-based neutron source for BNCT. We already designed a novel Beam Shape Assembly which meets the IAEA criteria for BNCT treatments. Using this BSA, in the present work, we characterize by Monte Carlo simulations the dose outside the neutron field. The out-of-field dose has been assessed via estimates using the ambient and equivalent dose. Also the boron uptake in healthy tissues has been analyzed for the equivalent dose computation. It is concluded that our design for a future accelerator-based source for BNCT meets reasonably well the criteria defined from other forms of radiotherapy on both equivalent and effective dose outside the field.
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Vento, V. (2017). Skyrmions at high density. Int. J. Mod. Phys. E, 26(1-2), 1740029–15pp.
Abstract: The phase diagram of quantum chromodynamics is conjectured to have a rich structure containing at least three forms of matter: hadronic nuclear matter, quarkyonic matter and quark-gluon plasma. We justify the origin of the quarkyonic phase transition in a chiral-quark model and describe its formulation in terms of Skyrme crystals.
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Vento, V. (2018). Skyrmions at high density. Phys. Part. Nuclei Lett., 15(4), 367–370.
Abstract: The phase diagram of quantum chromodynamics is conjectured to have a rich structure containing at least three forms of matter: hadronic nuclear matter, quarkyonic matter and quark gluon plasma. We describe its formulation in terms of Skyrme crystals and justify the origin of the quarkyonic phase transition in a chiral-quark model.
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Van Isacker, P., Algora, A., Vitéz-Sveiczer, A., Kiss, G. G., Orrigo, S. E. A., Rubio, B., et al. (2023). Gamow-Teller Beta Decay and Pseudo-SU(4) Symmetry. Symmetry-Basel, 15(11), 2001–15pp.
Abstract: We report on recent experimental results on beta decay into self-conjugate ( N = Z) nuclei with mass number 58 <= A <= 70. Super-allowed b decays from the J(pi) = 0(+) ground state of a Z = N + 2 parent nucleus are to the isobaric analogue state through so-called Fermi transitions and to J(pi) = 1(+) states by way of Gamow-Teller (GT) transitions. The operator of the latter decay is a generator of Wigner's SU(4) algebra and as a consequence GT transitions obey selection rules associated with this symmetry. Since SU(4) is progressively broken with increasing A, mainly as a consequence of the spinorbit interaction, this symmetry is not relevant for the nuclei considered here. We argue, however, that the pseudo-spin-orbit splitting can be small in nuclei with 58 <= A <= 70, in which case nuclear states exhibit an approximate pseudo-SU(4) symmetry. To test this conjecture, GT decay strength is calculated with use of a schematic Hamiltonian with pseudo-SU(4) symmetry. Some generic features of the GT beta decay due to pseudo-SU(4) symmetry are pointed out. The experimentally observed GT strength indicates a restoration of pseudo-SU(4) symmetry for A = 70.
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