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Perez-Perez, J.; Amare, J.C.; Bandac, I.C.; Bayo, A.; Borjabad-Sanchez, S.; Calvo-Mozota, J.M.; Cid-Barrio, L.; Hernandez-Antolin, R.; Hernandez-Molinero, B.; Novella, P.; Pelczar, K.; Pena-Garay, C.; Romeo, B.; Ortiz de Solorzano, A.; Sorel, M.; Torrent, J.; Uson, A.; Wojna-Pelczar, A.; Zuzel, G. |
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Title |
Radon Mitigation Applications at the Laboratorio Subterráneo de Canfranc (LSC) |
Type |
Journal Article |
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Year |
2022 |
Publication |
Universe |
Abbreviated Journal |
Universe |
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Volume |
8 |
Issue |
2 |
Pages |
112 - 20pp |
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Keywords |
radon; neutrinos; HPGe-detector; LSC |
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Abstract |
The Laboratorio Subterraneo de Canfranc (LSC) is the Spanish national hub for low radioactivity techniques and the associated scientific and technological applications. The concentration of the airborne radon is a major component of the radioactive budget in the neighborhood of the detectors. The LSC hosts a Radon Abatement System, which delivers a radon suppressed air with 1.1 & PLUSMN;0.2 mBq/m(3) of Rn-222. The radon content in the air is continuously monitored with an Electrostatic Radon Monitor. Measurements with the double beta decay demonstrators NEXT-NEW and CROSS and the gamma HPGe detectors show the important reduction of the radioactive background due to the purified air in the vicinity of the detectors. We also discuss the use of this facility in the LSC current program which includes NEXT-100, low background biology experiments and radiopure copper electroformation equipment placed in the radon-free clean room. |
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Address |
[Perez-Perez, Javier; Bandac, Iulian Catalin; Bayo, Alberto; Borjabad-Sanchez, Silvia; Calvo-Mozota, Jose Maria; Cid-Barrio, Laura; Hernandez-Antolin, Rebecca; Hernandez-Molinero, Beatriz; Pena-Garay, Carlos; Romeo, Beatriz] Lab Subterraneo Canfranc LSC, Canfranc Estn 22880, Spain, Email: javier.perez.perez@uj.edu.pl; |
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Mdpi |
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English |
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WOS:000762509500001 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5143 |
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Author |
Perez-Calatayud, J.; Ballester, F.; Tedgren, C.; DeWerd, L.A.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Vijande, J. |
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Title |
GEC-ESTRO ACROP recommendations on calibration and traceability of HE HDR-PDR photon-emitting brachytherapy sources at the hospital level |
Type |
Journal Article |
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Year |
2022 |
Publication |
Radiotherapy and Oncology |
Abbreviated Journal |
Radiother. Oncol. |
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Volume |
176 |
Issue |
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Pages |
108-117 |
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Keywords |
Brachytherapy; High energy; Calibration; Dosimetry; HDR-PDR |
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Abstract |
The vast majority of radiotherapy departments in Europe using brachytherapy (BT) perform temporary implants of high-or pulsed-dose rate (HDR-PDR) sources with photon energies higher than 50 keV. Such techniques are successfully applied to diverse pathologies and clinical scenarios. These recommen-dations are the result of Working Package 21 (WP-21) initiated within the BRAchytherapy PHYsics Quality Assurance System (BRAPHYQS) GEC-ESTRO working group with a focus on HDR-PDR source cal-ibration. They provide guidance on the calibration of such sources, including practical aspects and issues not specifically accounted for in well-accepted societal recommendations, complementing the BRAPHYQS WP-18 Report dedicated to low energy BT photon emitting sources (seeds). The aim of this report is to provide a European-wide standard in HDR-PDR BT source calibration at the hospital level to maintain high quality patient treatments. |
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Address |
[Perez-Calatayud, Jose] La Fe Hosp, Radiotherapy Dept, Valencia, Spain, Email: javier.vijande@uv.es |
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Elsevier Ireland Ltd |
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English |
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ISSN |
0167-8140 |
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WOS:000880438000006 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5466 |
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Author |
Perez Adan, D.; Bahl, H.; Grohsjean, A.; Martin Lozano, V.; Schwanenberger, C.; Weiglein, G. |
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Title |
A new LHC search for dark matter produced via heavy Higgs bosons using simplified models |
Type |
Journal Article |
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Year |
2023 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
151 - 27pp |
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Keywords |
Dark Matter at Colliders; Specific BSM Phenomenology |
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Abstract |
Searches for dark matter produced via scalar resonances in final states consisting of Standard Model (SM) particles and missing transverse momentum are of high relevance at the LHC. Motivated by dark-matter portal models, most existing searches are optimized for unbalanced decay topologies for which the missing momentum recoils against the visible SM particles. In this work, we show that existing searches are also sensitive to a wider class of models, which we characterize by a recently presented simplified model framework. We point out that searches for models with a balanced decay topology can be further improved with more dedicated analysis strategies. For this study, we investigate the feasibility of a new search for bottom-quark associated neutral Higgs production with a b (b) over barZ + p(T)(miss) final state and perform a detailed collider analysis. Our projected results in the different simplified model topologies investigated here can be easily reinterpreted in a wide range of models of physics beyond the SM, which we explicitly demonstrate for the example of the Two-Higgs-Doublet model with an additional pseudoscalar Higgs boson. |
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Address |
[Adan, Danyer Perez; Schwanenberger, Christian; Weiglein, Georg] Deutsch Elektronen Synchrotron DESY, Notkestr 85, D-22607 Hamburg, Germany, Email: danyer.perez.adan@desy.de; |
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Springer |
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English |
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ISSN |
1029-8479 |
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Notes |
WOS:001073505200003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5702 |
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Author |
Peppa, V.; Thomson, R.M.; Enger, S.A.; Fonseca, G.P.; Lee, C.N.; Lucero, J.N.E.; Mourtada, F.; Siebert, F.A.; Vijande, J.; Papagiannis, P. |
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Title |
A MC-based anthropomorphic test case for commissioning model-based dose calculation in interstitial breast 192-Ir HDR brachytherapy |
Type |
Journal Article |
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Year |
2023 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
50 |
Issue |
7 |
Pages |
4675-4687 |
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Keywords |
anthropomorphic phantom; commissioning; HDR brachytherapy; model based dose calculation algorithms; Monte Carlo |
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Abstract |
PurposeTo provide the first clinical test case for commissioning of Ir-192 brachytherapy model-based dose calculation algorithms (MBDCAs) according to the AAPM TG-186 report workflow. Acquisition and Validation MethodsA computational patient phantom model was generated from a clinical multi-catheter Ir-192 HDR breast brachytherapy case. Regions of interest (ROIs) were contoured and digitized on the patient CT images and the model was written to a series of DICOM CT images using MATLAB. The model was imported into two commercial treatment planning systems (TPSs) currently incorporating an MBDCA. Identical treatment plans were prepared using a generic Ir-192 HDR source and the TG-43-based algorithm of each TPS. This was followed by dose to medium in medium calculations using the MBDCA option of each TPS. Monte Carlo (MC) simulation was performed in the model using three different codes and information parsed from the treatment plan exported in DICOM radiation therapy (RT) format. Results were found to agree within statistical uncertainty and the dataset with the lowest uncertainty was assigned as the reference MC dose distribution. Data Format and Usage NotesThe dataset is available online at ,. Files include the treatment plan for each TPS in DICOM RT format, reference MC dose data in RT Dose format, as well as a guide for database users and all files necessary to repeat the MC simulations. Potential ApplicationsThe dataset facilitates the commissioning of brachytherapy MBDCAs using TPS embedded tools and establishes a methodology for the development of future clinical test cases. It is also useful to non-MBDCA adopters for intercomparing MBDCAs and exploring their benefits and limitations, as well as to brachytherapy researchers in need of a dosimetric and/or a DICOM RT information parsing benchmark. Limitations include specificity in terms of radionuclide, source model, clinical scenario, and MBDCA version used for its preparation. |
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Address |
[Peppa, Vasiliki; Papagiannis, Panagiotis] Natl & Kapodistrian Univ Athens, Med Sch, Med Phys Lab, Athens, Greece, Email: ppapagi@med.uoa.gr |
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Wiley |
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English |
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ISSN |
0094-2405 |
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Notes |
WOS:000989616100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5529 |
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Author |
Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J. |
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Title |
Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source |
Type |
Journal Article |
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Year |
2024 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
14 |
Issue |
1 |
Pages |
11448 - 12pp |
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Abstract |
Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range. |
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Address |
[Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es |
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Publisher |
Nature Portfolio |
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English |
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ISSN |
2045-2322 |
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Notes |
WOS:001228252900017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
6143 |
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