Abstract: During single clock inflation, hidden fields (i.e. fields coupled to the inflaton only gravitationally) in their adiabatic vacua can ordinarily only affect observables through virtual effects. After renormalizing background quantities (fixed by observations at some pivot scale), all that remains are logarithmic runnings in correlation functions that are both Planck and slow roll suppressed. In this paper we show how a large number of hidden fields can partially compensate this suppression and generate a potentially observable running in the tensor two point function, consistently inferable courtesy of a large N resummation. We detour to address certain subtleties regarding loop corrections during inflation, extending the analysis of [1]. Our main result is that one can extract bounds on the hidden field content of the universe from bounds on violations of the consistency relation between the tensor spectral index and the tensor to scalar ratio, were primordial tensors ever detected. Such bounds are more competitive than the naive bound inferred from requiring inflation to occur below the strong coupling scale of gravity if deviations from the consistency relation can be bounded to within the sub-percent level. We discuss how one can meaningfully constrain the parameter space of various phenomenological scenarios and constructions that address naturalness with a large number of species (such as N-naturalness') with CMB observations up to cosmic variance limits, and possibly future 21cm and gravitational wave observations.

Abstract: We extend the correspondence between metric-affine Ricci-Based Gravity the- ories and General Relativity (GR) to the case in which the matter sector is represented by linear and nonlinear electromagnetic fields. This complements previous studies focused on fluids and scalar fields. We establish the general algorithm that relates the matter fields in the GR and RBG frames and consider some applications. In particular, we find that the so-called Eddington-inspired Born-Infeld gravity theory coupled to Maxwell electromag- netism is in direct correspondence with GR coupled to Born-Infeld electromagnetism. We comment on the potential phenomenological implications of this relation.

Abstract: We explore the origin of Majorana masses within the majoron model and how this can lead to the generation of a distinguishable primordial stochastic background of gravitational waves. We first show how in the simplest majoron model only a contribution from cosmic string can be within the reach of planned experiments. We then consider extensions containing multiple complex scalars, demonstrating how in this case a spectrum comprising contributions from both a strong first order phase transition and cosmic strings can naturally emerge. We show that the interplay between multiple scalar fields can amplify the phase transition signal, potentially leading to double peaks over the wideband sloped spectrum from cosmic strings. We also underscore the possibility of observing such a gravitational wave background to provide insights into the reheating temperature of the universe. We conclude highlighting how the model can be naturally combined with scenarios addressing the origin of matter of the universe, where baryogenesis occurs via leptogenesis and a right-handed neutrino plays the role of dark matter.

Abstract: In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.

Abstract: Recent Cosmic Microwave Background (CMB) results from the Planck satellite, combined with previous CMB data and Hubble constant measurements from the Hubble Space Telescope, provide a constraint on the effective number of relativistic degrees of freedom 3.62(-0.48)(+0.50) at 95% CL. New Planck data provide a unique opportunity to place limits on models containing relativistic species at the decoupling epoch. We present here the bounds on sterile neutrino models combining Planck data with galaxy clustering information. Assuming N-eff active plus sterile massive neutrino species, in the case of a Planck+WP+HighL+HST analysis we find m(nu,sterile)(eff) < 0.36 eV and 3.14 < N-eff < 4.15 at 95% CL, while using Planck+WP+HighL data in combination with the full shape of the galaxy power spectrum from the Baryon Oscillation Spectroscopic Survey BOSS Data Relase 9 measurements, we find that 3.30 < N-eff < 4.43 and m(nu,sterile)(eff) < 0.33 eV both at 95% CL with the three active neutrinos having the minimum mass allowed in the normal hierarchy scheme, i.e. Sigma m(nu) similar to 0.06 eV. These values compromise the viability of the (3 + 2) massive sterile neutrino models for the parameter region indicated by global fits of neutrino oscillation data. Within the (3 + 1) massive sterile neutrino scenario, we find m(nu,sterile)(eff) < 0.34 eV at 95% CL. While the existence of one extra sterile massive neutrino state is compatible with current oscillation data, the values for the sterile neutrino mass preferred by oscillation analyses are significantly higher than the current cosmological bound. We review as well the bounds on extended dark sectors with additional light species based on the latest Planck CMB observations.