Abstract: Geometry construction is a fundamental aspect of any radiation transport simulation, regardless of the Monte Carlo code being used. Typically, this process is tedious, time-consuming, and error-prone. The conventional approach involves defining geometries using mathematical objects or surfaces. However, this method comes with several limitations, especially when dealing with complex models, particularly those with organic shapes. Furthermore, since each code employs its own format and methodology for defining geometries, sharing and reproducing simulations among researchers becomes a challenging task. Consequently, many codes have implemented support for simulating over geometries constructed via Computer-Aided Design (CAD) tools. Unfortunately, this feature is lacking in penRed and other PENELOPE physics-based codes. Therefore, the objective of this work is to implement such support within the penRed framework. New version program summary Program Title: Parallel Engine for Radiation Energy Deposition (penRed) CPC Library link to program files: https://doi.org/10.17632/rkw6tvtngy.2 Developer's repository link: https://github.com/PenRed/PenRed Code Ocean capsule: https://codeocean.com/capsule/1041417/tree Licensing provisions: GNU Affero General Public License v3 Programming language: C++ standard 2011. Journal reference of previous version: V. Gimenez-Alventosa, V. Gimenez Gomez, S. Oliver, PenRed: An extensible and parallel Monte-Carlo framework for radiation transport based on PENELOPE, Computer Physics Communications 267 (2021) 108065. doi:https://doi.org/10.1016/j.cpc.2021.108065. Does the new version supersede the previous version?: Yes Reasons for the new version: Implements the capability to simulate on CAD constructed geometries, among many other features and fixes. Summary of revisions: All changes applied through the code versions are summarized in the file CHANGELOG.md in the repository package. Nature of problem: While Monte Carlo codes have proven valuable in simulating complex radiation scenarios, they rely heavily on accurate geometrical representations. In the same way as many other Monte Carlo codes, penRed employs simple geometric quadric surfaces like planes, spheres and cylinders to define geometries. However, since these geometric models offer a certain level of flexibility, these representations have limitations when it comes to simulating highly intricate and irregular shapes. Anatomic structures, for example, require detailed representations of organs, tissues and bones, which are difficult to achieve using basic geometric objects. Similarly, complex devices or intricate mechanical systems may have designs that cannot be accurately represented within the constraints of such geometric models. Moreover, when the complexity of the model increases, geometry construction process becomes more difficult, tedious, time-consuming and error-prone [2]. Also, as each Monte Carlo geometry library uses its own format and construction method, reproducing the same geometry among different codes is a challenging task. Solution method: To face the problems stated above, the objective of this work is to implement the capability to simulate using irregular and adaptable meshed geometries in the penRed framework. This kind of meshes can be constructed using Computer-Aided Design (CAD) tools, the use of which is very widespread and streamline the design process. This feature has been implemented in a new geometry module named “MESH_BODY” specific for this kind of geometries. This one is freely available and usable within the official penRed package1. It can be used since penRed version 1.9.3b and above.

Abstract: Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.

Abstract: The next-generation water Cherenkov Hyper-Kamiokande detector will be able to detect thousands of neutrino events from a galactic Supernova explosion via Inverse Beta Decay processes followed by neutron capture on Gadolinium. This superb statistics provides a unique window to set bounds on neutrino properties, as its mass and lifetime. We shall explore the capabilities of such a future detector, constraining the former two properties via the time delay and the flux suppression induced in the Supernovae neutrino time and energy spectra. Special attention will be devoted to the statistically sub-dominant elastic scattering induced events, normally neglected, which can substantially improve the neutrino mass bound via time delays. When allowing for a invisible decaying scenario, the 95% CL lower bound on tau/m\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\tau /m$$\end{document} is almost one order of magnitude better than the one found with SN1987A neutrino events. Simultaneous limits can be set on both m nu\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$m\nu $$\end{document} and tau nu\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\tau {\nu }$$\end{document}, combining the neutrino flux suppression with the time-delay signature: the best constrained lifetime is that of nu 1\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\nu 1$$\end{document}, which has the richest electronic component. We find tau nu 1 greater than or similar to 4x105\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\tau {\nu _1}\gtrsim 4\times 10<^>5$$\end{document} s at 95% CL. The tightest 95% CL bound on the neutrino mass we find is 0.34 eV, which is not only competitive with the tightest neutrino mass limits nowadays, but also comparable to future laboratory direct mass searches. Both mass and lifetime limits are independent on the mass ordering, which makes our results very robust and relevant.

Abstract: We analyze theoretically the coupled-channel meson-baryon interaction with global flavor c<overline>cssn and c<overline>csss, where mesons are pseudoscalars or vectors, and baryons have JP = 1/2+ or 3/2+. The aim is to explore whether the nonlinear dynamics inherent in the unitarization process within coupled channels can dynamically generate double- and triple-strange pentaquark-type states (Pcss and Pcsss, respectively), for which there is no experimental evidence to date. We evaluate the s-wave scattering matrix by implementing unitarity in coupled channels, using potential kernels obtained from t-channel vector meson exchange. The required PPV and VVV vertices are obtained from Lagrangians derived through appropriate extensions of the local hidden gauge symmetry approach to the charm sector, while capitalizing on the symmetry of the spin and flavor wave function to evaluate the BBV vertex. We find four different poles in the double strange sector, some of them degenerate in spin. For the triple-strange channel, we find the meson-baryon interaction insufficient to generate a bound or resonance state through the unitary coupled-channel dynamics.

Abstract: We examine the contribution of tensor modes, in addition to the dominant scalar ones, on the temperature anisotropies of the cosmic microwave background (CMB). To this end, we analyze in detail the temperature two -point angular correlation function C(Theta) from the Planck 2018 dataset, focusing on large angles (Theta greater than or similar to 120 degrees) corresponding to small l multipoles. A hierarchical set of infrared cutoffs are naturally introduced to the scalar and tensor power spectra of the CMB by invoking an extra Kaluza-Klein spatial dimension compactifying at about the grand unified theory scale between the Planck epoch and the start of inflation. We associate this set of lower scalar and tensor cutoffs with the parity of the multipole expansion of the C(Theta) function. By fitting the Planck 2018 data we compute the multipole coefficients, thereby reproducing the well-known odd -parity preference in angular correlations seen by all three satellite missions: Cosmic Background Explorer, WMAP, and Planck. Our fits improve significantly once tensor modes are included in the analysis, hence providing a hint of the imprints of primordial gravitational waves on the temperature correlations observed in the CMB today. To conclude, we suggest a relationship between, on the one hand, the lack of (positive) large -angle correlations and the odd -parity dominance in the CMB and, on the other hand, the effect of primordial gravitational waves on the CMB temperature anisotropies.