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Baran, J. et al, & Brzezinski, K. (2024). Feasibility of the J-PET to monitor the range of therapeutic proton beams. Phys. Medica, 118, 103301–9pp.
Abstract: Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application.
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Balbinot, R., & Fabbri, A. (2024). The Unruh Vacuum and the “In-Vacuum” in Reissner-Nordström Spacetime. Universe, 10(1), 18–14pp.
Abstract: The Unruh vacuum is widely used as a quantum state to describe black hole evaporation since, near the horizon, it reproduces the physical state of a quantum field, the so-called “in-vacuum”, in the case where a black hole is formed by gravitational collapse. We examine the relation between these two quantum states in the background spacetime of a Reissner-Nordstrom black hole (both extremal and not), highlighting the similarities and striking differences.
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Balaudo, A., Calore, F., De Romeri, V., & Donato, F. (2024). NAJADS: a self-contained framework for the direct determination of astrophysical J-factors. J. Cosmol. Astropart. Phys., 02(2), 001–33pp.
Abstract: Cosmological simulations play a pivotal role in understanding the properties of the dark matter (DM) distribution in both galactic and galaxy -cluster environments. The characterization of DM structures is crucial for informing indirect DM searches, aiming at the detection of the annihilation (or decay) products of DM particles. A fundamental quantity in these analyses is the astrophysical J -factor. In the DM phenomenology community, J -factors are typically computed through the semi -analytical modelling of the DM mass distribution, which is affected by large uncertainties. With the scope of addressing and possibly reducing these uncertainties, we present NAJADS, a self-contained framework to derive the DM J -factor directly from the raw simulations data. We show how this framework can be used to compute all -sky maps of the J -factor, automatically accounting for the complex 3D structure of the simulated halos and for the boosting of the signal due to the density fluctuations along the line of sight. After validating our code, we present a proof -of -concept application of NAJADS to a realistic halo from the IllustrisTNG suite, and exploit it to make a thorough comparison between our numerical approach and traditional semi -analytical methods. JCAP02(2024)001
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Baeza-Ballesteros, J., Donini, A., Molina-Terriza, G., Monrabal, F., & Simon, A. (2024). Towards a realistic setup for a dynamical measurement of deviations from Newton's 1/r2 law: the impact of air viscosity. Eur. Phys. J. C, 84(6), 596–20pp.
Abstract: A novel experimental setup to measure deviations from the 1/r(2) distance dependence of Newtonian gravity was proposed in Donini and Marimon (Eur Phys J C 76:696, 2016). The underlying theoretical idea was to study the orbits of a microscopically-sized planetary system composed of a “Satellite”, with mass m(S) similar to O(10-9) g, and a “Planet”, with mass M-P similar to O(10-5) g at an initial distance of hundreds of microns. The detection of precession of the orbit in this system would be an unambiguous indication of a central potential with terms that scale with the distance differently from 1/r. This is a huge advantage with respect to the measurement of the absolute strength of the attraction between two bodies, as most electrically-induced background potentials do indeed scale as 1/r. Detection of orbit precession is unaffected by these effects, allowing for better sensitivities. In Baeza-Ballesteros et al. (Eur Phys J C 82:154, 2022), the impact of other subleading backgrounds that may induce orbit precession, such as, e.g., the electrical Casimir force or general relativity, was studied in detail. It was found that the proposed setup could test Yukawa-like corrections, alpha x exp(-r/lambda), to the 1/r potential with couplings as low as alpha similar to 10(-2) for distances as small as lambda similar to 10 μm, improving by roughly an order of magnitude present bounds. In this paper, we start to move from a theoretical study of the proposal to a more realistic implementation of the experimental setup. As a first step, we study the impact of air viscosity on the proposed setup and see how the setup should be modified in order to preserve the theoretical sensitivity achieved in Donini and Marimon (2016) and Baeza-Ballesteros et al. (2022).
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Baeza-Ballesteros, J., Bijnens, J., Husek, T., Romero-Lopez, F., Sharpe, S. R., & Sjo, M. (2024). The three-pion K-matrix at NLO in ChPT. J. High Energy Phys., 03(3), 048–43pp.
Abstract: The three-particle K-matrix, K-df,K-3, is a scheme-dependent quantity that parametrizes short-range three-particle interactions in the relativistic-field-theory three-particle finite-volume formalism. In this work, we compute its value for systems of three pions in all isospin channels through next-to-leading order in Chiral Perturbation Theory, generalizing previous work done at maximum isospin. We obtain analytic expressions through quadratic order (or cubic order, in the case of zero isospin) in the expansion about the three-pion threshold.
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