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Author (down) Roman, F.L.; Abler, D.; Kanellopoulos, V.; Amoros, G.; Davies, J.; Dosanjh, M.; Jena, R.; Kirkby, N.; Peach, K.; Salt, J.
Title Hadron therapy information sharing prototype Type Journal Article
Year 2013 Publication Journal of Radiation Research Abbreviated Journal J. Radiat. Res.
Volume 54 Issue Pages 56-60
Keywords hadron therapy; proton therapy; data federation; web portal; eHealth; cancer informatics
Abstract The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and reporting methods, as well as the approach to software sustainability achieved through the use of community-supported open-source components.
Address [Roman, Faustin Laurentiu; Abler, Daniel; Kanellopoulos, Vassiliki; Dosanjh, Manjit] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: faustin.roman@medaustron.at
Corporate Author Thesis
Publisher Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3060 ISBN Medium
Area Expedition Conference
Notes WOS:000321463900008 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1519
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Author (down) Poley, L.; Stolzenberg, U.; Schwenker, B.; Frey, A.; Gottlicher, P.; Marinas, C.; Stanitzki, M.; Stelzer, B.
Title Mapping the material distribution of a complex structure in an electron beam Type Journal Article
Year 2021 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 16 Issue 1 Pages P01010 - 33pp
Keywords Detector modelling and simulations I (interaction of radiation with matter, interaction of photons with matter, interaction of hadrons with matter, etc); Particle tracking detectors; Detector design and construction technologies and materials
Abstract The simulation and analysis of High Energy Physics experiments require a realistic simulation of the detector material and its distribution. The challenge is to describe all active and passive parts of large scale detectors like ATLAS in terms of their size, position and material composition. The common method for estimating the radiation length by weighing individual components, adding up their contributions and averaging the resulting material distribution over extended structures provides a good general estimate, but can deviate significantly from the material actually present. A method has been developed to assess its material distribution with high spatial resolution using the reconstructed scattering angles and hit positions of high energy electron tracks traversing an object under investigation. The study presented here shows measurements for an extended structure with a highly inhomogeneous material distribution. The structure under investigation is an End-of-Substructure-card prototype designed for the ATLAS Inner Tracker strip tracker – a PCB populated with components of a large range of material budgets and sizes. The measurements presented here summarise requirements for data samples and reconstructed electron tracks for reliable image reconstruction of large scale, inhomogeneous samples, choices of pixel sizes compared to the size of features under investigation as well as a bremsstrahlung correction for high material densities and thicknesses.
Address [Poley, L.; Stelzer, B.] Simon Fraser Univ, Dept Phys, Univ Dr, Burnaby, BC, Canada, Email: APoley@cern.ch
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000608273000010 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4687
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Author (down) Piersanti, L.; Bellini, F.; Bini, F.; Collamati, F.; De Lucia, E.; Durante, M.; Faccini, R.; Ferroni, F.; Fiore, S.; Iarocci, E.; La Tessa, C.; Marafini, M.; Mattei, I.; Patera, V.; Ortega, P.G.; Sarti, A.; Schuy, C.; Sciubba, A.; Vanstalle, M.; Voena, C.
Title Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u C-12 beam Type Journal Article
Year 2014 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 59 Issue 7 Pages 1857-1872
Keywords drift chamber; LYSO; hadrontherapy; carbon ion beam; dose monitoring
Abstract The radiation used in hadrontherapy treatments interacts with the patient body producing secondary particles, either neutral or charged, that can be used for dose and Bragg peak monitoring and to provide a fast feedback on the treatment plans. Recent results obtained from the authors on simplified setups (mono-energetic primary beams interacting with homogeneous tissue like target) have already indicated the correlation that exists between the flux of these secondaries coming from the target (e.g. protons and photons) and the position of the primary beam Bragg peak. In this paper, the measurements of charged particle fluxes produced by the interaction of a 220 MeV/u carbon ion beam at GSI, Darmstadt, with a polymethyl methacrylate target are reported. The emission region of protons (p), deuterons (d) and tritons (t) has been characterized using a drift chamber while the particle time-of-flight, used to compute the kinetic energy spectra, was measured with a LYSO scintillator.The energy released in the LYSO crystal was used for particle identification purposes. The measurements were repeated with the setup at 60 degrees and 90 degrees with respect to the primary beam direction. The accuracy on the fragments emission profile reconstruction and its relationship with the Bragg peak position have been studied. Based on the acquired experimental evidence, a method to monitor the dose profile and the position of the Bragg peak inside the target is proposed.
Address [Piersanti, L.; De Lucia, E.; Iarocci, E.; Mattei, I.; Sarti, A.] Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy, Email: vincenzo.patera@lnf.infn.it
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000333186200020 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1735
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Author (down) Perez-Ramos, R.; Mathieu, V.; Sanchis-Lozano, M.A.
Title Heavy quark flavour dependence of multiparticle production in QCD jets Type Journal Article
Year 2010 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 08 Issue 8 Pages 047 - 24pp
Keywords Jets; Hadronic Colliders; QCD
Abstract After inserting the heavy quark mass dependence into QCD partonic evolution equations, we determine the mean charged hadron multiplicity and second multiplicity correlators of jets produced in high energy collisions. We thereby extend the so-called dead cone effect to the phenomenology of multiparticle production in QCD jets and find that the average multiplicity of heavy-quark initiated jets decreases significantly as compared to the massless case, even taking into account the weak decay products of the leading primary quark. We emphasize the relevance of our study as a complementary check of b-tagging techniques at hadron colliders like the Tevatron and the LHC.
Address [Perez-Ramos, Redamy] Univ Valencia, CSIC, Dept Fis Teor, E-46100 Burjassot, Spain, Email: redamy.perez@uv.es
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1126-6708 ISBN Medium
Area Expedition Conference
Notes ISI:000282368500019 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ elepoucu @ Serial 356
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Author (down) PANDA Collaboration (Singh, B. et al); Diaz, J.
Title Technical design report for the (P)over-barANDA Barrel DIRC detector Type Journal Article
Year 2019 Publication Journal of Physics G Abbreviated Journal J. Phys. G
Volume 46 Issue 4 Pages 045001 - 155pp
Keywords particle identification; ring imaging Cherenkov detector; DIRC counter; PANDA experiment; hadron physics
Abstract The (P) over bar ANDA (anti-Proton ANnihiliation at DArmstadt) experiment will be one of the four flagship experiments at the new international accelerator complex FAIR (Facility for Antiproton and Ion Research) in Darmstadt, Germany. (P) over bar ANDA will address fundamental questions of hadron physics and quantum chromodynamics using high-intensity cooled antiproton beams with momenta between 1.5 and 15 GeV/c and a design luminosity of up to 2 x 10(32) cm(-2) S-1. Excellent particle identification (PID) is crucial to the success of the (P) over bar ANDA physics program. Hadronic PID in the barrel region of the target spectrometer will be performed by a fast and compact Cherenkov counter using the detection of internally reflected Cherenkov light (DIRC) technology. It is designed to cover the polar angle range from 22 degrees to 140 degrees and will provide at least 3 standard deviations (s.d.) pi/K separation up to 3.5 GeV/c, matching the expected upper limit of the final state kaon momentum distribution from simulation. This documents describes the technical design and the expected performance of the (P) over bar ANDA Barrel DIRC detector. The design is based on the successful BaBar DIRC with several key improvements. The performance and system cost were optimized in detailed detector simulations and validated with full system prototypes using particle beams at GSI and CERN. The final design meets or exceeds the PID goal of clean pi/K separation with at least 3 s.d. over the entire phase space of charged kaons in the Barrel DIRC.
Address [Singh, B.] Aligarth Muslim Univ, Phys Dept, Aligarh, India, Email: j.schwiening@gsi.de
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0954-3899 ISBN Medium
Area Expedition Conference
Notes WOS:000460153900001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3930
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Author (down) Oset, E.; Albaladejo, M.; Xie, J.J.; Ramos, A.
Title Recent developments on hadron interaction and dynamically generated resonances Type Journal Article
Year 2014 Publication International Journal of Modern Physics E Abbreviated Journal Int. J. Mod. Phys. E
Volume 23 Issue 7 Pages 1461008 - 8pp
Keywords Hadron interaction; dynamically generated resonances
Abstract In this talk I report on the recent developments in the subject of dynamically generated resonances. In particular I discuss the gamma p -> K-0 Sigma+ and gamma n -> K-0 Sigma(0) reactions, with a peculiar behavior around the K*(0)Lambda threshold, due to a 1/2(-) resonance around 2035 MeV. Similarly, I discuss a BES experiment, J/psi -> eta K*(0) (K) over bar*(0) decay, which provides evidence for a new h(1) resonance around 1830 MeV that was predicted from the vector-vector interaction. A short discussion is then made about recent advances in the charm and beauty sectors.
Address [Oset, E.; Albaladejo, M.; Ramos, A.] Univ Valencia, Inst Invest Paterna, Ctr Mixto, Dept Fis Teor,CSIC, Valencia 46071, Spain, Email: oset@ific.uv.es
Corporate Author Thesis
Publisher World Scientific Publ Co Pte Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0218-3013 ISBN Medium
Area Expedition Conference
Notes WOS:000341934000009 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1946
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Author (down) Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Nacher, E.; Tain, J.L.; Tolosa, A.
Title On the performance of large monolithic LaCl3(Ce) crystals coupled to pixelated silicon photosensors Type Journal Article
Year 2018 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 13 Issue Pages P03014 - 17pp
Keywords Compton imaging; Detector modelling and simulations I (interaction of radiation with matter interaction of photons with matter interaction of hadrons with matter etc); Gamma detectors (scintillators CZT HPG HgI etc); Instrumentation and methods for time-of-flight (TOF); spectroscopy
Abstract We investigate the performance of large area radiation detectors, with high energy-and spatial-resolution, intended for the development of a Total Energy Detector with gamma-ray imaging capability, so-called i-TED. This new development aims for an enhancement in detection sensitivity in time-of-flight neutron capture measurements, versus the commonly used C6D6 liquid scintillation total-energy detectors. In this work, we study in detail the impact of the readout photosensor on the energy response of large area (50 x 50 mm(2)) monolithic LaCl3(Ce) crystals, in particular when replacing a conventional mono-cathode photomultiplier tube by an 8 x 8 pixelated silicon photomultiplier. Using the largest commercially available monolithic SiPM array (25 cm(2)), with a pixel size of 6 x 6 mm(2), we have measured an average energy resolution of 3.92% FWHM at 662 keV for crystal thick-nesses of 10, 20 and 30 mm. The results are confronted with detailed Monte Carlo (MC) calculations, where optical processes and properties have been included for the reliable tracking of the scintillation photons. After the experimental validation of the MC model, we use our MC code to explore the impact of a smaller photosensor segmentation on the energy resolution. Our optical MC simulations predict only a marginal deterioration of the spectroscopic performance for pixels of 3 x 3 mm(2).
Address [Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Tain, J. L.; Tolosa, A.] Univ Valencia, CSIC, Inst Fis Corpuscular, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: Luis.Caballero@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000428146300004 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 3542
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Author (down) Muñoz, E.; Barrio, J.; Etxebeste, A.; Ortega, P.G.; Lacasta, C.; Oliver, J.F.; Solaz, C.; Llosa, G.
Title Performance evaluation of MACACO: a multilayer Compton camera Type Journal Article
Year 2017 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 62 Issue 18 Pages 7321-7341
Keywords Compton imaging; Compton camera; continuous LaBr3 crystal; silicon photomultiplier; hadron therapy
Abstract Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm.
Address [Munoz, Enrique; Barrio, John; Etxebeste, Ane; Ortega, Pablo G.; Lacasta, Carlos; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000408229900003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3253
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Author (down) Muñoz, E.; Barrio, J.; Bemmerer, D.; Etxebeste, A.; Fiedler, F.; Hueso-Gonzalez, F.; Lacasta, C.; Oliver, J.F.; Romer, K.; Solaz, C.; Wagner, L.; Llosa, G.
Title Tests of MACACO Compton telescope with 4.44 MeV gamma rays Type Journal Article
Year 2018 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 13 Issue Pages P05007 - 13pp
Keywords Compton imaging; Instrumentation for hadron therapy; Gamma detectors (scintillators, CZT, HPG, HgI etc); Photon detectors for UV, visible and IR photons (solid state) (PIN diodes, APDs, Si PMTs, G APDs, CCDs, EBCCDs, EMCCDs etc)
Abstract Hadron therapy offers the possibility of delivering a large amount of radiation dose to tumors with minimal absorption by the surrounding healthy tissue. In order to fully exploit the advantages of this technique, the use of real-time beam monitoring devices becomes mandatory. Compton imaging devices can be employed to map the distribution of prompt gamma emission during the treatment and thus assess its correct delivery. The Compton telescope prototype developed at IFIC-Valencia for this purpose is made of three layers of LaBr3 crystals coupled to silicon photomultipliers. The system has been tested in a 4.44 MeV gamma field at the 3 MV Tandetron accelerator at HZDR, Dresden. Images of the target with the system in three different positions separated by 10 mm were successfully reconstructed. This indicates the ability of MACACO for imaging the prompt gamma rays emitted at such energies.
Address [Munoz, E.; Barrio, J.; Etxebeste, A.; Lacasta, C.; Oliver, J. F.; Solaz, C.; Llosa, G.] Univ Valencia, CSIC, Inst Fis Corpuscular, Parque Cient,C Catedrat Jose Beltran 2, E-46980 Paterna, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000431716900001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3575
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Author (down) Muñoz, E.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F.
Title A spectral reconstruction algorithm for two-plane Compton cameras Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue 2 Pages 025011 - 17pp
Keywords Compton imaging; Compton camera; hadron therapy; image reconstruction
Abstract One factor limiting the current applicability extent of hadron therapy is the lack of a reliable method for real time treatment monitoring. The use of Compton imaging systems as monitors requires the correct reconstruction of the distribution of prompt gamma productions during patient irradiation. In order to extract the maximum information from all the measurable events, we implemented a spectral reconstruction method that assigns to all events a probability of being either partial or total energy depositions. The method, implemented in a list-mode maximum likelihood expectation maximization algorithm, generates a four dimensional image in the joint spatial-spectral domain, in which the voxels containing the emission positions and energies are obtained. The analytical model used for the system response function is also employed to derive an analytical expression for the sensitivity, which is calculated via Monte Carlo integration. The performance of the method is evaluated through reconstruction of various experimental and simulated sources with different spatial and energy distributions. The results show that the proposed method can recover the spectral and spatial information simultaneously, but only under the assumption of ideal measurements. The analysis of the Monte Carlo simulations has led to the identification of two important degradation sources: the mispositioning of the gamma interaction point and the missing energy recorded in the interaction. Both factors are related to the high energy transferred to the recoil electrons, which can travel far from the interaction point and even escape the detector. These effects prevent the direct application of the current method in more realistic scenarios. Nevertheless, experimental point-like sources have been accurately reconstructed and the spatial distributions and spectral emission of complex simulated phantoms can be identified.
Address [Munoz, Enrique; Barrientos, Luis; Bernabeu, Jose; Borja-Lloret, Marina; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000520111400001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4332
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