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Author Olivares Herrador, J.; Latina, A.; Aksoy, A.; Fuster Martinez, N.; Gimeno, B.; Esperante, D. doi  openurl
  Title Implementation of the beam-loading effect in the tracking code RF-track based on a power-diffusive model Type Journal Article
  Year 2024 Publication Frontiers in Physics Abbreviated Journal Front. Physics  
  Volume 12 Issue Pages 1348042 - 11pp  
  Keywords beam loading; LINAC; energy loss; tracking simulation; transient; high-intensity beam; CLEAR; gradient reduction  
  Abstract The need to achieve high energies in particle accelerators has led to the development of new accelerator technologies, resulting in higher beam intensities and more compact devices with stronger accelerating fields. In such scenarios, beam-loading effects occur, and intensity-dependent gradient reduction affects the accelerated beam as a consequence of its interaction with the surrounding cavity. In this study, a power-diffusive partial differential equation is derived to account for this effect. Its numerical resolution has been implemented in the tracking code RF-Track, allowing the simulation of apparatuses where transient beam loading plays an important role. Finally, measurements of this effect have been carried out in the CERN Linear Electron Accelerator for Research (CLEAR) facility at CERN, finding good agreement with the RF-Track simulations.  
  Address [Olivares Herrador, Javier; Latina, Andrea; Aksoy, Avni] CERN, Meyrin, Switzerland, Email: javier.olivares.herrador@cern.ch  
  Corporate Author Thesis  
  Publisher Frontiers Media Sa Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2296-424x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001193122800001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 6019  
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Author Oliver, S.; Vijande, J.; Tejedor-Aguilar, N.; Miro, R.; Rovira-Escutia, J.J.; Ballester, F.; Juste, B.; Carmona, V.; Felici, G.; Verdu, G.; Sanchis, E.; Conde, A.; Perez-Calatayud, J. doi  openurl
  Title Monte Carlo flattening filter design to high energy intraoperative electron beam homogenization Type Journal Article
  Year 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.  
  Volume 212 Issue Pages 111102 - 6pp  
  Keywords Intraoperative radiotherapy; Electron portable LinAc; Flattening filter; Dosimetry; Monte Carlo  
  Abstract Intraoperative radiotherapy using mobile linear accelerators is used for a wide variety of malignancies. However, when large fields are used in combination with high energies, a deterioration of the flatness dose profile is measured with respect to smaller fields and lower energies. Indeed, for the LIAC HWL of Sordina, this deterioration is observed for the 12 MeV beam combined with 10 cm (or larger) diameter applicator. Aimed to solve this problem, a flattening filter has been designed and validated evaluating the feasibility of its usage at the upper part of the applicator. The design of the filter was based on Monte Carlo simulations because of its accuracy in modeling components of clinical devices, among other purposes. The LIAC 10 cm diameter applicator was modeled and simulated independently by two different research groups using two different MC codes, reproducing the heterogeneity of the 12 MeV energy beam. Then, an iterative process of filter design was carried out. Finally, the MC designed conical filter with the optimal size and height to obtain the desired flattened beam was built in-house using a 3D printer. During the experimental validation of the applicator-filter, percentage depth dose, beam profiles, absolute and peripheral dose measurements were performed to demonstrate the effectiveness of the filter addition in the applicator. These measurements conclude that the beam has been flattened, from 5.9% with the standard configuration to 1.6% for the configuration with the filter, without significant increase of the peripheral dose. Consequently, the new filter-applicator LIAC configuration can be used also in a conventional surgery room. A reduction of 16% of the output dose and a reduction of 1.1 mm in the D50 of the percentage depth dose was measured with respect to the original configuration. This work is a proof-of-concept that demonstrates that it is possible to add a filter able to flatten the beam delivered by the Sordina LIAC HWL. Future studies will focus on more refined technical solutions fully compatible with the integrity of the applicator, including its sterilization, to be safely introduced in the clinical practice.  
  Address [Oliver, S.; Miro, R.; Juste, B.; Verdu, G.] Univ Polite cn Vale ncia, Inst Segur Ind Radiofis & Medioambiental ISIRYM, Cami Vera S-N, Valencia 46022, Spain, Email: gverdu@iqn.upv.es  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0969-806x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001026194900001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5578  
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Author Verdu-Andres, S.; Amaldi, U.; Faus-Golfe, A. doi  openurl
  Title CABOTO, a high-gradient linac for hadrontherapy Type Journal Article
  Year 2013 Publication Journal of Radiation Research Abbreviated Journal J. Radiat. Res.  
  Volume 54 Issue Pages 155-161  
  Keywords hadrontherapy; high-gradient linac; cyclinac; carbon ion therapy; multipainting  
  Abstract The field of hadrontherapy has grown rapidly in recent years. At present the therapeutic beam is provided by a cyclotron or a synchrotron, but neither cyclotrons nor synchrotrons present the best performances for hadrontherapy. The new generation of accelerators for hadrontherapy should allow fast active energy modulation and have a high repetition rate, so that moving organs can be appropriately treated in a reasonable time. In addition, a reduction of the dimensions and cost of the accelerators for hadrontherapy would make the acquisition and operation of a hadrontherapy facility more affordable, which would translate into great benefits for the potential hadrontherapy patients. The 'cyclinac', an accelerator concept that combines a cyclotron with a high-frequency linear accelerator (linac), is a fast-cycling machine specifically conceived to allow for fast active energy modulation. The present paper focuses on CABOTO (CArbon BOoster for Therapy in Oncology), a compact, efficient high-frequency linac that can accelerate C6+ ions and H-2 molecules from 150-410 MeV/u in similar to 24 m. The paper presents the latest design of CABOTO and discusses its performances.  
  Address [Verdu-Andres, Silvia; Amaldi, Ugo] Fdn Tera, I-28100 Novara, Italy, Email: sverdu@bnl.gov  
  Corporate Author Thesis  
  Publisher Oxford Univ Press Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0449-3060 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000321463900021 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 1506  
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