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Assam, I., Vijande, J., Ballester, F., Perez-Calatayud, J., Poppe, B., & Siebert, F. A. (2022). Evaluation of dosimetric effects of metallic artifact reduction and tissue assignment on Monte Carlo dose calculations for I-125 prostate implants. Med. Phys., 49, 6195–6208.
Abstract: Purpose Monte Carlo (MC) simulation studies, aimed at evaluating the magnitude of tissue heterogeneity in I-125 prostate permanent seed implant brachytherapy (BT), customarily use clinical post-implant CT images to generate a virtual representation of a realistic patient model (virtual patient model). Metallic artifact reduction (MAR) techniques and tissue assignment schemes (TAS) are implemented on the post-implant CT images to mollify metallic artifacts due to BT seeds and to assign tissue types to the voxels corresponding to the bright seed spots and streaking artifacts, respectively. The objective of this study is to assess the combined influence of MAR and TAS on MC absorbed dose calculations in post-implant CT-based phantoms. The virtual patient models used for I-125 prostate implant MC absorbed dose calculations in this study are derived from the CT images of an external radiotherapy prostate patient without BT seeds and prostatic calcifications, thus averting the need to implement MAR and TAS. Methods The geometry of the IsoSeed I25.S17plus source is validated by comparing the MC calculated results of the TG-43 parameters for the line source approximation with the TG-43U1S2 consensus data. Four MC absorbed dose calculations are performed in two virtual patient models using the egs_brachy MC code: (1) TG-43-based D-w,w-TG(43), (2) D-w,D-w-MBDC that accounts for interseed scattering and attenuation (ISA), (3) D-m,D-m that examines ISA and tissue heterogeneity by scoring absorbed dose in tissue, and (4) D-w,D-m that unlike D-m,D-m scores absorbed dose in water. The MC absorbed doses (1) and (2) are simulated in a TG-43 patient phantom derived by assigning the densities of every voxel to 1.00 g cm(-3) (water), whereas MC absorbed doses (3) and (4) are scored in the TG-186 patient phantom generated by mapping the mass density of each voxel to tissue according to a CT calibration curve. The MC absorbed doses calculated in this study are compared with VariSeed v8.0 calculated absorbed doses. To evaluate the dosimetric effect of MAR and TAS, the MC absorbed doses of this work (independent of MAR and TAS) are compared to the MC absorbed doses of different I-125 source models from previous studies that were calculated with different MC codes using post-implant CT-based phantoms generated by implementing MAR and TAS on post-implant CT images. Results The very good agreement of TG-43 parameters of this study and the published consensus data within 3% validates the geometry of the IsoSeed I25.S17plus source. For the clinical studies, the TG-43-based calculations show a D-90 overestimation of more than 4% compared to the more realistic MC methods due to ISA and tissue composition. The results of this work generally show few discrepancies with the post-implant CT-based dosimetry studies with respect to the D-90 absorbed dose metric parameter. These discrepancies are mainly Type B uncertainties due to the different I-125 source models and MC codes. Conclusions The implementation of MAR and TAS on post-implant CT images have no dosimetric effect on the I-125 prostate MC absorbed dose calculation in post-implant CT-based phantoms.
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ATLAS and CMS Collaborations(Aaboud, M. et al), Alvarez Piqueras, D., Aparisi Pozo, J. A., Bailey, A. J., Barranco Navarro, L., Cabrera Urban, S., et al. (2019). Combinations of single-top-quark production cross-section measurements and vertical bar f(LV)V(tb)vertical bar determinations at root s=7 and 8 TeV with the ATLAS and CMS experiments. J. High Energy Phys., 05(5), 088–81pp.
Abstract: This paper presents the combinations of single-top-quark production cross-section measurements by the ATLAS and CMS Collaborations, using data from LHC proton-proton collisions at = 7 and 8 TeV corresponding to integrated luminosities of 1.17 to 5.1 fb(-1) at = 7 TeV and 12.2 to 20.3 fb(-1) at = 8 TeV. These combinations are performed per centre-of-mass energy and for each production mode: t-channel, tW, and s-channel. The combined t-channel cross-sections are 67.5 +/- 5.7 pb and 87.7 +/- 5.8 pb at = 7 and 8 TeV respectively. The combined tW cross-sections are 16.3 +/- 4.1 pb and 23.1 +/- 3.6 pb at = 7 and 8 TeV respectively. For the s-channel cross-section, the combination yields 4.9 +/- 1.4 pb at = 8 TeV. The square of the magnitude of the CKM matrix element V-tb multiplied by a form factor f(LV) is determined for each production mode and centre-of-mass energy, using the ratio of the measured cross-section to its theoretical prediction. It is assumed that the top-quark-related CKM matrix elements obey the relation |V-td|, |V-ts| << |V-tb|. All the |f(LV)V(tb)|(2) determinations, extracted from individual ratios at = 7 and 8 TeV, are combined, resulting in |f(LV)V(tb)| = 1.02 +/- 0.04 (meas.) +/- 0.02 (theo.). All combined measurements are consistent with their corresponding Standard Model predictions.
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ATLAS and CMS Collaborations(Aad, G. et al), Aikot, A., Amos, K. R., Aparisi Pozo, J. A., Bailey, A. J., Bouchhar, N., et al. (2024). Evidence for the Higgs Boson Decay to a Z Boson and a Photon at the LHC. Phys. Rev. Lett., 132(2), 021803–32pp.
Abstract: The first evidence for the Higgs boson decay to a Z boson and a photon is presented, with a statistical significance of 3.4 standard deviations. The result is derived from a combined analysis of the searches performed by the ATLAS and CMS Collaborations with proton -proton collision datasets collected at the CERN Large Hadron Collider (LHC) from 2015 to 2018. These correspond to integrated luminosities of around 140 fb-1 for each experiment, at a center -of -mass energy of 13 TeV. The measured signal yield is 2.2 +/- 0.7 times the standard model prediction, and agrees with the theoretical expectation within 1.9 standard deviations.
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ATLAS and CMS Collaborations(Aad, G. et al), Aparisi Pozo, J. A., Bailey, A. J., Cabrera Urban, S., Cardillo, F., Castillo Gimenez, V., et al. (2023). Combination of inclusive top-quark pair production cross-section measurements using ATLAS and CMS data at √s=7 and 8 TeV. J. High Energy Phys., 07(7), 213–64pp.
Abstract: A combination of measurements of the inclusive top-quark pair production cross-section performed by ATLAS and CMS in proton-proton collisions at centre-of-mass energies of 7 and 8TeV at the LHC is presented. The cross-sections are obtained using top-quark pair decays with an opposite-charge electron-muon pair in the final state and with data corresponding to an integrated luminosity of about 5 fb(-1) at root s = 7 TeV and about 20 fb(-1) at root s = 8TeV for each experiment. The combined cross-sections are determined to be 178.5 +/- 4.7 pb at root s = 7 TeV and 243.3(-5.9)(+6.0) pb at root s = 8TeV with a correlation of 0.41, using a reference top-quark mass value of 172.5 GeV. The ratio of the combined crosssections is determined to be R-8/7 = 1.363 +/- 0.032. The combined measured cross-sections and their ratio agree well with theory calculations using several parton distribution function (PDF) sets. The values of the top-quark pole mass (with the strong coupling fixed at 0.118) and the strong coupling (with the top-quark pole mass fixed at 172.5 GeV) are extracted from the combined results by fitting a next-to-next-to-leading-order plus next-to-next-to-leading-log QCD prediction to the measurements. Using a version of the NNPDF3.1 PDF set containing no top-quark measurements, the results obtained are m(t)(pole) = 173.4(-2.0)(+1.8) GeV and alpha s(m(Z)) = 0.1170(-0.0018)(+0.0021).
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ATLAS and CMS Collaborations(Aad, G. et al), Aparisi Pozo, J. A., Bailey, A. J., Cabrera Urban, S., Castillo, F. L., Castillo Gimenez, V., et al. (2020). Combination of the W boson polarization measurements in top quark decays using ATLAS and CMS data at root s=8 TeV. J. High Energy Phys., 08(8), 051–67pp.
Abstract: The combination of measurements of the W boson polarization in top quark decays performed by the ATLAS and CMS collaborations is presented. The measurements are based on proton-proton collision data produced at the LHC at a centre-of-mass energy of 8 TeV, and corresponding to an integrated luminosity of about 20 fb(-1)for each experiment. The measurements used events containing one lepton and having different jet multiplicities in the final state. The results are quoted as fractions of W bosons with longitudinal (F-0), left-handed (F-L), or right-handed (F-R) polarizations. The resulting combined measurements of the polarization fractions are F-0= 0.693 +/- 0.014 and F-L= 0.315 +/- 0.011. The fractionF(R)is calculated from the unitarity constraint to be F-R=-0.008 +/- 0.007. These results are in agreement with the standard model predictions at next-to-next-to-leading order in perturbative quantum chromodynamics and represent an improvement in precision of 25 (29)% for F-0(F-L) with respect to the most precise single measurement. A limit on anomalous right-handed vector (V-R), and left- and right-handed tensor (g(L), g(R)) tWb couplings is set while fixing all others to their standard model values. The allowed regions are [-0.11,0.16] for V-R, [-0.08,0.05] for g(L), and [-0.04,0.02] for g(R), at 95% confidence level. Limits on the corresponding Wilson coefficients are also derived.
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ATLAS Collaboration. (2022). A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery. Nature, 607(7917), 52–59.
Abstract: The standard model of particle physics(1-4) describes the known fundamental particles and forces that make up our Universe, with the exception of gravity. One of the central features of the standard model is a field that permeates all of space and interacts with fundamental particles(5-9). The quantum excitation of this field, known as the Higgs field, manifests itself as the Higgs boson, the only fundamental particle with no spin. In 2012, a particle with properties consistent with the Higgs boson of the standard model was observed by the ATLAS and CMS experiments at the Large Hadron Collider at CERN10,11. Since then, more than 30 times as many Higgs bosons have been recorded by the ATLAS experiment, enabling much more precise measurements and new tests of the theory. Here, on the basis of this larger dataset, we combine an unprecedented number of production and decay processes of the Higgs boson to scrutinize its interactions with elementary particles. Interactions with gluons, photons, and W and Z bosons-the carriers of the strong, electromagnetic and weak forces-are studied in detail. Interactions with three third-generation matter particles (bottom (b) and top (t) quarks, and tau leptons (tau)) are well measured and indications of interactions with a second-generation particle (muons, mu) are emerging. These tests reveal that the Higgs boson discovered ten years ago is remarkably consistent with the predictions of the theory and provide stringent constraints on many models of new phenomena beyond the standard model.
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ATLAS Collaboration(Aaboud, M. et al), Alvarez Piqueras, D., Aparisi Pozo, J. A., Bailey, A. J., Barranco Navarro, L., Cabrera Urban, S., et al. (2023). Measurement of the inclusive t(t)over-bar production cross section in the lepton plus jets channel in pp collisions at √s=7 TeV with the ATLAS detector using support vector machines. Phys. Rev. D, 108(3), 032014–34pp.
Abstract: A measurement of the top quark pair-production cross section in the lepton + jets decay channel is presented. It is based on 4.6 fb(-1) of root s = 7 TeV pp collision data collected during 2011 by the ATLAS experiment at the CERN Large Hadron Collider. A three-class, multidimensional event classifier based on support vector machines is used to differentiate t (T) over bar events from backgrounds. The tt production cross section is found to be sigma(t (t) over bar) = 168.5 +/- 0.7(stat)(-5.9)(+6.2) (syst)(-3.2)(+3.4) (lumi) pb. The result is consistent with the Standard Model prediction based on QCD calculations at next-to-next-to-leading order.
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ATLAS Collaboration(Aaboud, M. et al), Alvarez Piqueras, D., Aparisi Pozo, J. A., Bailey, A. J., Barranco Navarro, L., Cabrera Urban, S., et al. (2021). Measurement of the relative B-c(+/-)/B-+/- production cross section with the ATLAS detector at root s=8 TeV. Phys. Rev. D, 104(1), 012010–26pp.
Abstract: The total cross section and differential cross sections for the production of B-c(+/-) mesons, times their branching fraction to J/psi pi(+/-), are measured relative to those for the production of B-+/- mesons, times their branching fraction to J/psi K-+/-. The data used for this study correspond to an integrated luminosity of 20.3 fb(-1) of pp collisions recorded by the ATLAS detector at the Large Hadron Collider in 2012 at a center-of-mass energy of root s = 8 TeV. The measurement is performed differentially in bins of transverse momentum p(T) for 13 GeV < p(T)(B-c(+/-)) < 22 GeV and p(T)(B-c(+/-)) > 22 GeV and in bins of rapidity y for vertical bar y vertical bar < 0.75 and 0.75 < vertical bar y vertical bar < 2.3. The relative cross section times branching fraction for the full range p(T) > 13 GeV and vertical bar y vertical bar < 2.3 is (0.34 +/- 0.04(stat) (+0.06)(-0.02 sys) +/- 0.01(lifetime))%. The differential measurements suggest that the production cross section of the B-c(+/-) decreases faster with p(T) than the production cross section of the B-+/-, while no significant dependence on rapidity is observed.
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ATLAS Collaboration(Aaboud, M. et al), Alvarez Piqueras, D., Aparisi Pozo, J. A., Bailey, A. J., Barranco Navarro, L., Cabrera Urban, S., et al. (2021). Measurement of the associated production of a Higgs boson decaying into b-quarks with a vector boson at high transverse momentum in pp collisions at root s=13 TeV with the ATLAS detector. Phys. Lett. B, 816, 136204–28pp.
Abstract: The associated production of a Higgs boson with a W or Z boson decaying into leptons and where the Higgs boson decays to a b (b) over bar pair is measured in the high vector-boson transverse momentum regime, above 250 GeV, with the ATLAS detector. The analysed data, corresponding to an integrated luminosity of 139 fb(-1), were collected in proton-proton collisions at the Large Hadron Collider between 2015 and 2018 at a centre-of-mass energy of root s = 13 TeV. The measured signal strength, defined as the ratio of the measured signal yield to that predicted by the Standard Model, is 0.72(-0.36)(+0.39) corresponding to an observed (expected) significance of 2.1 (2.7) standard deviations. Cross-sections of associated production of a Higgs boson decaying into b quark pairs with a W or Z gauge boson, decaying into leptons, are measured in two exclusive vector boson transverse momentum regions, 250-400 GeV and above 400 GeV, and interpreted as constraints on anomalous couplings in the framework of a Standard Model effective field theory.
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ATLAS Collaboration(Aaboud, M. et al), Alvarez Piqueras, D., Aparisi Pozo, J. A., Bailey, A. J., Barranco Navarro, L., Cabrera Urban, S., et al. (2020). Search for electroweak production of charginos and sleptons decaying into final states with two leptons and missing transverse momentum in root s=13 TeV pp collisions using the ATLAS detector. Eur. Phys. J. C, 80(2), 123–33pp.
Abstract: A search for the electroweak production of charginos and sleptons decaying into final states with two electrons or muons is presented. The analysis is based on 139 fb(-1) of proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider at v s = 13 TeV. Three R-parity-conserving scenarios where the lightest neutralino is the lightest supersymmetric particle are considered: the production of chargino pairs with decays via eitherW bosons or sleptons, and the direct production of slepton pairs. The analysis is optimised for the first of these scenarios, but the results are also interpreted in the others. No significant deviations from the Standard Model expectations are observed and limits at 95% confidence level are set on the masses of relevant supersymmetric particles in each of the scenarios. For a massless lightest neutralino, masses up to 420 GeV are excluded for the production of the lightest-chargino pairs assuming W-boson-mediated decays and up to 1 TeV for slepton-mediated decays, whereas for slepton-pair production masses up to 700 GeV are excluded assuming three generations of mass-degenerate sleptons.
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