Abstract: Detection of high-energy (>= 100 MeV) gamma rays by the Fermi Large Area Telescope from a nova in the symbiotic binary system V407 Cygni has opened the possibility of high-energy neutrino detection from this type of source. A thermonuclear explosion on the white dwarf surface sets off a nova shell in motion that expands and slows down in a dense surrounding medium provided by the red giant companion. Particles are accelerated in the shocks of the shell and interact with the surrounding medium to produce observed gamma rays. We show that proton-proton interaction, which is most likely responsible for producing gamma rays via neutral pion decay, produces >= 0:1 GeV neutrinos that can be detected by the current and future experiments at >= 10 GeV.