Abstract: We examine the maximum possible strength of the global 21-cm absorption dip on the cosmic background radiation at high-redshift caused by the atomic intergalactic medium, when the Lyman-alpha coupling is maximum, assuming no exotic cooling mechanisms from interactions with dark matter. This maximum absorption is limited by three inevitable factors that need to be accounted for: (a) heating by energy transferred from the cosmic background radiation to the hydrogen atoms via 21-cm transitions, dubbed as 21-cm heating; (b) Ly alpha heating by scatterings of Ly alpha photons from the first stars; (c) the impact of the expected density fluctuations in the intergalactic gas in standard cold dark matter theory, which reduces the mean 21-cm absorption signal. Inclusion of this third novel effect reduces the maximum global 21-cm absorption by similar to 10%. Overall, the three effects studied here reduce the 21-cm global absorption by similar to 20% at z similar or equal to 17.