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Author (up) Barrientos, L.; Borja-Lloret, M.; Casaña, J.V.; Dendooven, P.; Garcia Lopez, J.G.; Hueso-Gonzalez, F.; Jiméeez-Ramos, M.C.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G. doi  openurl
  Title Gamma-ray sources imaging and test-beam results with MACACO III Compton camera Type Journal Article
  Year 2024 Publication Physica Medica Abbreviated Journal Phys. Medica  
  Volume 117 Issue Pages 103199 - 10pp  
  Keywords Hadron therapy; Compton camera; Scintillator crystals; Silicon photomultipliers  
  Abstract Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s.  
  Address [Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es  
  Corporate Author Thesis  
  Publisher Elsevier Sci Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1120-1797 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001145147400001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5892  
Permanent link to this record
 

 
Author (up) Barrientos, L.; Borja-Lloret, M.; Casana, J.V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G. doi  openurl
  Title System characterization and performance studies with MACACO III Compton camera Type Journal Article
  Year 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.  
  Volume 208 Issue Pages 110922 - 13pp  
  Keywords Compton camera; Scintillator crystals; Silicon photomultipliers  
  Abstract The IRIS group of IFIC-Valencia has developed a Compton camera prototype. The system detectors are made of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. Two models of silicon photomultipliers arrays with different micro pixel pitch (25 and 50 μm) have been chosen as possible candidates to improve the response of the new system. Characterization studies with a 22Na point-like source have indicated that the 25 μm photodetector provided better performance in terms of energy resolution (5.2% FWHM at 511 keV) and angular resolution (6.9 degrees FWHM at 1275 keV), and more stability with temperature variations. In addition, MACACO III imaging capabilities have been assessed using a structure composed of thirty-seven 22Na point-like sources. Furthermore, in order to evaluate possible ways of improving the system performance, several studies have been carried out by means of simulations both in realistic and performance improved conditions. In this work, the system performance is evaluated for its future application in different areas.  
  Address [Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IF, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es;  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0969-806x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000962800400001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5511  
Permanent link to this record
 

 
Author (up) Barrientos, L.; Borja-Lloret, M.; Etxebeste, A.; Muñoz, E.; Oliver, J.F.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G. doi  openurl
  Title Performance evaluation of MACACO II Compton camera Type Journal Article
  Year 2021 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 1014 Issue Pages 165702 - 7pp  
  Keywords Compton camera; Hadron therapy; LaBr3; Silicon photomultipliers  
  Abstract The IRIS group at IFIC-Valencia has developed a second version of a Compton camera prototype for hadron therapy treatment monitoring, with the aim of improving the performance with respect to its predecessor. The system is composed of three Lanthanum (III) bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs). The detector energy resolution has been improved to 5.6% FWHM at 511 keV and an angular resolution of 8.0 degrees has been obtained. Images of a Na-22 point-like source have been reconstructed selecting two and three interaction events. Moreover, the experimental data have been reproduced with Monte Carlo simulations using a Compton camera module (CCMod) in GATE v8.2 obtaining a good correlation.  
  Address [Barrientos, L.; Borja-Lloret, M.; Munoz, E.; Oliver, J. F.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] Univ Valencia, Inst Fis Corpuscular, CSIC, Valencia, Spain, Email: lbarrien@ific.uv.es  
  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000701263400010 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 4976  
Permanent link to this record
 

 
Author (up) Real, D.; Calvo, D. doi  openurl
  Title Silicon Photomultipliers for Neutrino Telescopes Type Journal Article
  Year 2023 Publication Universe Abbreviated Journal Universe  
  Volume 9 Issue 7 Pages 326 - 14pp  
  Keywords silicon photomultipliers; neutrino telescopes; time to digital converters; electronics acquisition  
  Abstract Neutrino astronomy has opened a new window to the extreme Universe, entering into a fruitful era built upon the success of neutrino telescopes, which have already given a new step forward in this novel and growing field by the first observation of steady point-like sources already achieved by IceCube. Neutrino telescopes equipped with Silicon PhotoMultipliers (SiPMs) will significantly increase in number, because of their excellent time resolution and the angular resolution, and will be in better condition to detect more steady sources as well as the unexpected. The use of SiPMs represents a challenge to the acquisition electronics because of the fast signals as well as the high levels of dark noise produced by SiPMs. The acquisition electronics need to include a noise rejection scheme by implementing a coincidence filter between channels. This work discusses the advantages and disadvantages of using SiPMs for the next generation of neutrino telescopes, focusing on the possible developments that could help for their adoption in the near future.  
  Address [Real, Diego; Calvo, David] Univ Valencia, Inst Fis Corpuscular, CSIC, IFIC, C Catedrat Jose Beltran 2, Valencia 46980, Spain, Email: real@ific.uv.es  
  Corporate Author Thesis  
  Publisher Mdpi Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001038900800001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5593  
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Author (up) Real, D.; Calvo, D.; Zornoza, J.D.; Manzaneda, M.; Gozzini, R.; Ricolfe-Viala, C.; Lajara, R.; Albiol, F. doi  openurl
  Title Fast Coincidence Filter for Silicon Photomultiplier Dark Count Rate Rejection Type Journal Article
  Year 2024 Publication Sensors Abbreviated Journal Sensors  
  Volume 24 Issue 7 Pages 2084 - 12pp  
  Keywords time-to-digital converters; neutrino telescopes; silicon photomultipliers; dark noise rate filtering  
  Abstract Silicon Photomultipliers find applications across various fields. One potential Silicon Photomultiplier application domain is neutrino telescopes, where they may enhance the angular resolution. However, the elevated dark count rate associated with Silicon Photomultipliers represents a significant challenge to their widespread utilization. To address this issue, it is proposed to use Silicon Photomultipliers and Photomultiplier Tubes together. The Photomultiplier Tube signals serve as a trigger to mitigate the dark count rate, thereby preventing undue saturation of the available bandwidth. This paper presents an investigation into a fast and resource-efficient method for filtering the Silicon Photomultiplier dark count rate. A low-resource and fast coincident filter has been developed, which removes the Silicon Photomultiplier dark count rate by using as a trigger the Photomultiplier Tube input signals. The architecture of the coincidence filter, together with the first results obtained, which validate the effectiveness of this method, is presented.  
  Address [Real, Diego; Calvo, David; Zornoza, Juan de Dios; Manzaneda, Mario; Gozzini, Rebecca; Albiol, Francisco] CSIC Univ Valencia, IFIC Inst Fis Corpuscular, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: real@ific.uv.es;  
  Corporate Author Thesis  
  Publisher Mdpi Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001201226600001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 6063  
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Author (up) Viegas, R.; Roser, J.; Barrientos, L.; Borja-Lloret, M.; Casaña, J.V.; Lopez, J.G.; Jimenez-Ramos, M.C.; Hueso-Gonzalez, F.; Ros, A.; Llosa, G. doi  openurl
  Title Characterization of a Compton camera based on the TOFPET2 ASIC Type Journal Article
  Year 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.  
  Volume 202 Issue Pages 110507 - 11pp  
  Keywords Compton camera; Hadron therapy; LaBr3; PETsys TOFPET2; Silicon photomultipliers  
  Abstract The use of Compton cameras for medical imaging and its interest as a hadron therapy treatment monitoring has increased in the last decade with the development of silicon photomultipliers. MACACOp is a Compton camera prototype designed and assembled at the IRIS group of IFIC-Valencia. This Compton camera is based on monolithic Lanthanum (III) Bromide crystals and silicon photomultipliers, and employs the novel TOFPET2 ASIC as readout electronics. This system emerged as an alternative to MACACO II prototype, with the aim of improving its limited time resolution. To test the performance of the ASIC in a Compton camera setup, the prototype was characterized, both in laboratory and in-beam. A time resolution of 1.5 ns was obtained after time corrections, which improves greatly the performance of the MACACO II. Moreover, the results obtained at high photon energies demonstrate the ability of the system to obtain 1 mm displacements of the reconstructed spots. The results reinforce the potential of the system as a monitoring device for hadron therapy.  
  Address [Viegas, R.; Roser, J.; Barrientos, L.; Borja-Lloret, M.; Casana, J., V; Hueso-Gonzalez, F.; Ros, A.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Rita.Viegas@ific.uv.es  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0969-806x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000870840600006 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5392  
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