Abstract: In light of the recent R-K(*) data on neutral current flavor anomalies in B -> K-(*())l(+)l(-) decays, we reexamine their quantitative interpretation in terms of an extended 331 gauge theory framework. We achieve this by adding two extra lepton species with novel 331 charges, while ensuring that the model remains anomaly-free. In contrast to the canonical 331 models, the gauge charges of the first and second lepton families differ from each other, allowing lepton-flavor universality violation. We further expand the model by adding the neutral fermions required to provide an adequate description for small neutrino masses.