Abstract: General neutrino-scalar couplings appear in many extensions of the Standard Model. We can probe these neutrino-scalar couplings by a leptonic decay of mesons and from a heavy neutrino search. Our analysis improves the present limits to vertical bar g(e)vertical bar(2) < 1.9 x 10(-6) and vertical bar g(mu)vertical bar(2) < 1.9 x 10(-7) at 90% C.L. for massless scalars. For massive scalars, we found for the first time the constraints for g(alpha)(2) couplings to be 10(-6) – 10(-1), respectively, for scalar masses between up 100 MeV, and we have no limits for masses above 300 MeV.