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Author (up) Carles, M.; Lerche, C.W.; Sanchez, F.; Mora, F.; Benlloch, J.M.
Title Position correction with depth of interaction information for a small animal PET system Type Journal Article
Year 2011 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 648 Issue Pages S176-S180
Keywords DOI; PET; Positioning algorithm; Gamma ray imaging; Continuous scintillators
Abstract In this work we study the effects on the spatial resolution when depth of interaction (001) information is included in the parameterization of the line of response (LOR) for a small animal positron emission tomography (PET) system. One of the most important degrading factors for PET is the parallax error introduced in systems that do not provide DOI information of the recorded gamma-rays. Our group has designed a simple and inexpensive method for DOI determination in continuous scintillation crystals. This method is based, on one hand, in the correlation between the scintillation light distribution width in monolithic crystals and the DOI, and, on the other hand, on a small modification of the widely applied charge dividing circuits (CDR). In this work we present a new system calibration that includes the DOI information, and also the development of the correction equations that relates the LOR without and with DOI information. We report the results obtained for different measurements along the transaxial field of view (FOV) and the image quality enhancement achieved specially at the edge of the FOV.
Address [Carles, M.; Sanchez, F.; Benlloch, J. M.] Inst Fis Corpuscular CSIC UV, Valencia 46071, Spain, Email: montcar@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000305376900046 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 1067
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Author (up) Pino, F.; Roe, N.; Orero, A.; Falcon, C.; Rojas, S.; Benlloch, J.M.; Ros, D.; Pavia, J.
Title Development of a variable-radius pinhole SPECT system with a portable gamma camera Type Journal Article
Year 2011 Publication Revista Española de Medicina Nuclear Abbreviated Journal Rev. Esp. Med. Nucl.
Volume 30 Issue 5 Pages 286-291
Keywords SPECT; Small animal; Pinhole; Portable gamma camera; Continuous scintillator
Abstract Objective: To develop a small-animal SPECT system using a low cost commercial portable gamma camera equipped with a pinhole collimator, a continuous scintillation crystal and a position-sensitive photomultiplier tube. Material and methods: The gamma camera was attached to a variable radius system, which enabled us to optimize sensitivity and resolution by adjusting the radius of rotation to the size of the object. To investigate the capability of the SPECT system for small animal imaging, the dependence of resolution and calibration parameters on radius was assessed and acquisitions of small phantoms and mice were carried out. Results: Resolution values, ranging from 1.0 mm for a radius of 21.4 mm and 1.4 mm for a radius of 37.2 mm were obtained, thereby justifying the interest of a variable radius SPECT system. Conclusions: The image quality of phantoms and animals were satisfactory, thus confirming the usefulness of the system for small animal SPECT imaging.
Address [Pino, F; Roe, N; Ros, D] Univ Barcelona, Fac Med, Unitat Biofis, Barcelona 7, Spain, Email: fpino@iconcologia.net
Corporate Author Thesis
Publisher Elsevier Science Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0212-6982 ISBN Medium
Area Expedition Conference
Notes WOS:000294659400004 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ elepoucu @ Serial 753
Permanent link to this record