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Author Amaldi, U.; Bonomi, R.; Braccini, S.; Crescenti, M.; Degiovanni, A.; Garlasche, M.; Garonna, A.; Magrin, G.; Mellace, C.; Pearce, P.; Pitta, G.; Puggioni, P.; Rosso, E.; Verdu-Andres, S.; Wegner, R.; Weiss, M.; Zennaro, R.
Title Accelerators for hadrontherapy: From Lawrence cyclotrons to linacs Type Journal Article
Year 2010 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 620 Issue 2-3 Pages 563-577
Keywords Medical accelerators; Linac; Cyclotron; Synchrotron; Cyclinac; Radiation oncology; Hadrontherapy; Particle therapy; Proton therapy; Carbon ion therapy; Dose delivery
Abstract Hadrontherapy with protons and carbon ions is a fast developing methodology in radiation oncology. The accelerators used and planned for this purpose are reviewed starting from the cyclotrons used in the thirties. As discussed in the first part of this paper, normal and superconducting cyclotrons are still employed, together with synchrotrons, for proton therapy while for carbon ion therapy synchrotrons have been till now the only option. The latest developments concern a superconducting cyclotron for carbon ion therapy, fast-cycling high frequency linacs and 'single room' proton therapy facilities. These issues are discussed in the second part of the paper by underlining the present challenges, in particular the treatment of moving organs.
Address [Amaldi, U.; Bonomi, R.; Braccini, S.; Crescenti, M.; Degiovanni, A.; Garlasche, M.; Garonna, A.; Magrin, G.; Mellace, C.; Pearce, P.; Pitta, G.; Puggioni, P.; Rosso, E.; Andres, S. Verdu; Wegner, R.; Weiss, M.; Zennaro, R.] TERA Fdn, Novara, Italy, Email: Saverio.Braccini@cern.ch
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes ISI:000280601700058 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 401
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Author Verdu-Andres, S.; Amaldi, U.; Faus-Golfe, A.
Title CABOTO, a high-gradient linac for hadrontherapy Type Journal Article
Year 2013 Publication Journal of Radiation Research Abbreviated Journal J. Radiat. Res.
Volume 54 Issue Pages 155-161
Keywords hadrontherapy; high-gradient linac; cyclinac; carbon ion therapy; multipainting
Abstract The field of hadrontherapy has grown rapidly in recent years. At present the therapeutic beam is provided by a cyclotron or a synchrotron, but neither cyclotrons nor synchrotrons present the best performances for hadrontherapy. The new generation of accelerators for hadrontherapy should allow fast active energy modulation and have a high repetition rate, so that moving organs can be appropriately treated in a reasonable time. In addition, a reduction of the dimensions and cost of the accelerators for hadrontherapy would make the acquisition and operation of a hadrontherapy facility more affordable, which would translate into great benefits for the potential hadrontherapy patients. The 'cyclinac', an accelerator concept that combines a cyclotron with a high-frequency linear accelerator (linac), is a fast-cycling machine specifically conceived to allow for fast active energy modulation. The present paper focuses on CABOTO (CArbon BOoster for Therapy in Oncology), a compact, efficient high-frequency linac that can accelerate C6+ ions and H-2 molecules from 150-410 MeV/u in similar to 24 m. The paper presents the latest design of CABOTO and discusses its performances.
Address [Verdu-Andres, Silvia; Amaldi, Ugo] Fdn Tera, I-28100 Novara, Italy, Email: sverdu@bnl.gov
Corporate Author Thesis
Publisher Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3060 ISBN Medium
Area Expedition Conference
Notes WOS:000321463900021 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1506
Permanent link to this record