Abstract: We consider the possibility of gauge coupling unification within the simplest realizations of the SU(3)(c) x SU(3)(L) x SU(3)(R) xU(1)(X) gauge theory. We present a first exploration of the renormalization group equations governing the “bottom-up” evolution of the gauge couplings in a generic model with free normalization for the generators. Interestingly, we find that for a SU(3)(c) x SU(3)(L) x SU(3)(R) x U(1)(X) symmetry breaking scale M-X as low as a few TeV one can achieve unification in the presence of leptonic octets. We briefly comment on possible grand unified theory frameworks which can embed the SU(3)(c) x SU(3)(L) x SU(3)(R) xU(1)(X) model as well as possible implications, such as lepton flavor violating physics at the LHC.