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Author (up) Hueso-Gonzalez, F.; Ballester, F.; Perez-Calatayud, J.; Siebert, F.A.; Vijande, J.
Title Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent I-125 prostate brachytherapy Type Journal Article
Year 2017 Publication Brachytherapy Abbreviated Journal Brachytherapy
Volume 16 Issue 3 Pages 616-623
Keywords Brachytherapy; Low-dose rate; Heterogeneities; Prostate; Calcifications; Dosimetry
Abstract PURPOSE: RayStretch is a simple algorithm proposed for heterogeneity corrections in low-dose-rate brachytherapy. It is built on top of TG-43 consensus data, and it has been validated with Monte Carlo (MC) simulations. In this study, we take a real clinical prostate implant with 71 1251 seeds as reference and we apply RayStretch to analyze its performance in worst-case scenarios. METHODS AND MATERIALS: To do so, we design two cases where large calcifications are located in the prostate lobules. RayStretch resilience under various calcification density values is also explored. Comparisons against MC calculations are performed. RESULTS: Dose volume histogram related parameters like prostate D-90, rectum D-2cc, or urethra D-10 obtained with RayStretch agree within a few percent with the detailed MC results for all cases considered. CONCLUSIONS: The robustness and compatibility of RayStretch with commercial treatment planning systems indicate its applicability in clinical practice for dosimetric corrections in prostate calcifications. Its use during intraoperative ultrasound planning is foreseen.
Address [Hueso-Gonzalez, Fernando] Target Systemelekt GmbH, Wuppertal, Germany, Email: javier.vijande@uv.es
Corporate Author Thesis
Publisher Elsevier Science Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1538-4721 ISBN Medium
Area Expedition Conference
Notes WOS:000402231600019 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3151
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