Abstract: This paper describes the new Antiproton Decelerator (AD) orbit measurement system and the Extra Low ENergy Antiproton ring (ELENA) orbit, trajectory and intensity measurement system. The AD machine at European Organization for Nuclear Research (CERN) is presently being used to decelerate antiprotons from 3.57 GeV/c to 100 MeV/c for matter vs anti-matter comparative studies. The ELENA machine, presently under commissioning, has been designed to provide an extra deceleration stage down to 13.7 MeV/c. The AD orbit system is based on 32 horizontal and 27 vertical electrostatic Beam Position Monitor (BPM) fitted with existing low noise front-end amplifiers while the ELENA system consists of 24 BPMs equipped with new low-noise head amplifiers. In both systems the front-end amplifiers generate a difference (delta) and a sum (sigma) signal which are sent to the digital acquisition system, placed tens of meters away from the AD or ELENA rings, where they are digitized and further processed. The beam position is calculated by dividing the difference signal by the sum signal either using directly the raw digitized data for measuring the turn-by-turn trajectory in the ELENA system or after down-mixing the signals to baseband for the orbit measurement in both machines. The digitized sigma signal will be used in the ELENA system to calculate the bunched beam intensity and the Schottky parameters with coasting beam after passing through different signal processing chain. The digital acquisition arrangement for both systems is based on the same hardware, also used in the ELENA Low Level Radio Frequency (LLRF) system, which follows the VME Switched Serial (VXS) enhancement of the Versa Module Eurocard 64x extension (VME64x) standard and includes VITA 57 standard Field Programmable Gate Array Mezzanine Card (FMC). The digital acquisition Field Programmable Gate Array (FPGA) andDigital Signal Processor (DSP) firmware sharesmany common functionalities with the LLRF system but has been tailored for this measurement application in particular. Specific control and acquisition software has been developed for these systems. Both systems are installed in AD and ELENA. The AD orbit system currently measures the orbit in AD while the ELENA system is being used in the commissioning of the ELENA ring.

Abstract: Motivated by the persistent anomalies reported in the b -> c tau v<overbar></mml:mover> data, we perform a general model-independent analysis of these transitions, in the presence of light right-handed neutrinos. We adopt an effective field theory approach and write a low-energy effective Hamiltonian, including all possible dimension-six operators. The corresponding Wilson coefficients are determined through a numerical fit to all available experimental data. In order to work with a manageable set of free parameters, we define eleven well- motivated scenarios, characterized by the different types of new physics that could mediate these transitions, and analyse which options seem to be preferred by the current measurements. The data exhibit a clear preference for new-physics contributions, and good fits to the data are obtained in several cases. However, the current measurement of the longitudinal D<SUP></SUP> polarization in B -> D tau v<overbar></mml:mover> cannot be easily accommodated within its experimental 1 sigma range. A general analysis of the three-body B -> D tau v<overbar></mml:mover> and four-body B -> D<mml:mo><mml:mfenced close=“)” open=“(”><mml:mo>-> D pi</mml:mfenced>tau <mml:mover accent=“true”>v<mml:mo stretchy=“true”><overbar></mml:mover> angular distributions is also presented. The accessible angular observables are studied in order to assess their sensitivity to the different new physics scenarios. Experimental information on these distributions would help to disentangle the dynamical origin of the current anomalies.

Abstract: PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy.

Abstract: Future dedicated radio interferometers, including HERA and SKA, are very promising tools that aim to study the epoch of reionization and beyond via measurements of the 21 cm signal from neutral hydrogen. Dark matter (DM) annihilations into charged particles change the thermal history of the Universe and, as a consequence, affect the 21 cm signal. Accurately predicting the effect of DM strongly relies on the modeling of annihilations inside halos. In this work, we use up-to-date computations of the energy deposition rates by the products from DM annihilations, a proper treatment of the contribution from DM annihilations in halos, as well as values of the annihilation cross section allowed by the most recent cosmological measurements from the Planck satellite. Given current uncertainties on the description of the astrophysical processes driving the epochs of reionization, X-ray heating and Lyman-alpha pumping, we find that disentangling DM signatures from purely astrophysical effects, related to early-time star formation processes or late-time galaxy X-ray emissions, will be a challenging task. We conclude that only annihilations of DM particles with masses of similar to 100 MeV, could leave an unambiguous imprint on the 21 cm signal and, in particular, on the 21cm power spectrum. This is in contrast to previous, more optimistic results in the literature, which have claimed that strong signatures might also be present even for much higher DM masses. Additional measurements of the 21cm signal at different cosmic epochs will be crucial in order to break the strong parameter degeneracies between DM annihilations and astrophysical effects and undoubtedly single out a DM imprint for masses different from similar to 100 MeV.

Abstract: The observation of space-time variations in fundamental constants would provide strong evidence for the existence of new light degrees of freedom in the theory of Nature. Robustly constraining such scenarios requires exploiting observations that span different scales and probe the state of the Universe at different epochs. In the context of cosmology, both the cosmic microwave background and the Lyman-a forest have proven to be powerful tools capable of constraining variations in electromagnetism, however at the moment there do not exist cosmological probes capable of bridging the gap between recombination and reionization. In the near future, radio telescopes will attempt to measure the 21 cm transition of neutral hydrogen during the epochs of reionization and the cosmic dawn (and potentially the tail end of the dark ages); being inherently sensitive to electromagnetic phenomena, these experiments will offer a unique perspective on space-time variations of the fine-structure constant and the electron mass. We show here that large variations in these fundamental constants would produce features on the 21 cm power spectrum that may be distinguishable from astrophysical uncertainties. Furthermore, we forecast the sensitivity for the Square Kilometer Array, and show that the 21 cm power spectrum may be able to constrain variations at the level of O(10(-3)).