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Author Muñoz, E.; Barrio, J.; Bernabeu, J.; Etxebeste, A.; Lacasta, C.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F.
Title Study and comparison of different sensitivity models for a two-plane Compton camera Type Journal Article
Year 2018 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 63 Issue 13 Pages 135004 - 19pp
Keywords Compton camera imaging; MLEM; Monte Carlo simulations; image quality
Abstract Given the strong variations in the sensitivity of Compton cameras for the detection of events originating from different points in the field of view (FoV), sensitivity correction is often necessary in Compton image reconstruction. Several approaches for the calculation of the sensitivity matrix have been proposed in the literature. While most of these models are easily implemented and can be useful in many cases, they usually assume high angular coverage over the scattered photon, which is not the case for our prototype. In this work, we have derived an analytical model that allows us to calculate a detailed sensitivity matrix, which has been compared to other sensitivity models in the literature. Specifically, the proposed model describes the probability of measuring a useful event in a two-plane Compton camera, including the most relevant physical processes involved. The model has been used to obtain an expression for the system and sensitivity matrices for iterative image reconstruction. These matrices have been validated taking Monte Carlo simulations as a reference. In order to study the impact of the sensitivity, images reconstructed with our sensitivity model and with other models have been compared. Images have been reconstructed from several simulated sources, including point-like sources and extended distributions of activity, and also from experimental data measured with Na-22 sources. Results show that our sensitivity model is the best suited for our prototype. Although other models in the literature perform successfully in many scenarios, they are not applicable in all the geometrical configurations of interest for our system. In general, our model allows to effectively recover the intensity of point-like sources at different positions in the FoV and to reconstruct regions of homogeneous activity with minimal variance. Moreover, it can be employed for all Compton camera configurations, including those with low angular coverage over the scatterer.
Address (down) [Munoz, Enrique; Barrio, John; Bernabeu, Jose; Etxebeste, Ane; Lacasta, Carlos; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, IFIC, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000436390800004 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 3639
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Author Muñoz, E.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F.
Title A spectral reconstruction algorithm for two-plane Compton cameras Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue 2 Pages 025011 - 17pp
Keywords Compton imaging; Compton camera; hadron therapy; image reconstruction
Abstract One factor limiting the current applicability extent of hadron therapy is the lack of a reliable method for real time treatment monitoring. The use of Compton imaging systems as monitors requires the correct reconstruction of the distribution of prompt gamma productions during patient irradiation. In order to extract the maximum information from all the measurable events, we implemented a spectral reconstruction method that assigns to all events a probability of being either partial or total energy depositions. The method, implemented in a list-mode maximum likelihood expectation maximization algorithm, generates a four dimensional image in the joint spatial-spectral domain, in which the voxels containing the emission positions and energies are obtained. The analytical model used for the system response function is also employed to derive an analytical expression for the sensitivity, which is calculated via Monte Carlo integration. The performance of the method is evaluated through reconstruction of various experimental and simulated sources with different spatial and energy distributions. The results show that the proposed method can recover the spectral and spatial information simultaneously, but only under the assumption of ideal measurements. The analysis of the Monte Carlo simulations has led to the identification of two important degradation sources: the mispositioning of the gamma interaction point and the missing energy recorded in the interaction. Both factors are related to the high energy transferred to the recoil electrons, which can travel far from the interaction point and even escape the detector. These effects prevent the direct application of the current method in more realistic scenarios. Nevertheless, experimental point-like sources have been accurately reconstructed and the spatial distributions and spectral emission of complex simulated phantoms can be identified.
Address (down) [Munoz, Enrique; Barrientos, Luis; Bernabeu, Jose; Borja-Lloret, Marina; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000520111400001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4332
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Author Muñoz, E.; Barrio, J.; Bemmerer, D.; Etxebeste, A.; Fiedler, F.; Hueso-Gonzalez, F.; Lacasta, C.; Oliver, J.F.; Romer, K.; Solaz, C.; Wagner, L.; Llosa, G.
Title Tests of MACACO Compton telescope with 4.44 MeV gamma rays Type Journal Article
Year 2018 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 13 Issue Pages P05007 - 13pp
Keywords Compton imaging; Instrumentation for hadron therapy; Gamma detectors (scintillators, CZT, HPG, HgI etc); Photon detectors for UV, visible and IR photons (solid state) (PIN diodes, APDs, Si PMTs, G APDs, CCDs, EBCCDs, EMCCDs etc)
Abstract Hadron therapy offers the possibility of delivering a large amount of radiation dose to tumors with minimal absorption by the surrounding healthy tissue. In order to fully exploit the advantages of this technique, the use of real-time beam monitoring devices becomes mandatory. Compton imaging devices can be employed to map the distribution of prompt gamma emission during the treatment and thus assess its correct delivery. The Compton telescope prototype developed at IFIC-Valencia for this purpose is made of three layers of LaBr3 crystals coupled to silicon photomultipliers. The system has been tested in a 4.44 MeV gamma field at the 3 MV Tandetron accelerator at HZDR, Dresden. Images of the target with the system in three different positions separated by 10 mm were successfully reconstructed. This indicates the ability of MACACO for imaging the prompt gamma rays emitted at such energies.
Address (down) [Munoz, E.; Barrio, J.; Etxebeste, A.; Lacasta, C.; Oliver, J. F.; Solaz, C.; Llosa, G.] Univ Valencia, CSIC, Inst Fis Corpuscular, Parque Cient,C Catedrat Jose Beltran 2, E-46980 Paterna, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000431716900001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3575
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Author Moretti, F.; Bombacigno, F.; Montani, G.
Title The Role of Longitudinal Polarizations in Horndeski and Macroscopic Gravity: Introducing Gravitational Plasmas Type Journal Article
Year 2021 Publication Universe Abbreviated Journal Universe
Volume 7 Issue 12 Pages 496 - 28pp
Keywords gravitational waves; gauge-invariant method; Landau damping; macroscopic gravity
Abstract We discuss some general and relevant features of longitudinal gravitational modes in Horndeski gravity and their interaction with matter media. Adopting a gauge-invariant formulation, we clarify how massive scalar and vector fields can induce additional transverse and longitudinal excitations, resulting in breathing, vector, and longitudinal polarizations. We review, then, the interaction of standard gravitational waves with a molecular medium, outlining the emergence of effective massive gravitons, induced by the net quadrupole moment due to molecule deformation. Finally, we investigate the interaction of the massive mode in Horndeski gravity with a noncollisional medium, showing that Landau damping phenomenon can occur in the gravitational sector as well. That allows us to introduce the concept of “gravitational plasma”, where inertial forces associated with the background field play the role of cold ions in electromagnetic plasma.
Address (down) [Moretti, Fabio; Montani, Giovanni] Sapienza Univ Rome, Dept Phys, Ple Aldo Moro 5, I-00185 Rome, Italy, Email: fabio.moretti@uniroma1.it;
Corporate Author Thesis
Publisher Mdpi Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes WOS:000741918900001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5076
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Author Montanari, D. et al; Gadea, A.
Title Probing the nature of particle-core couplings in Ca-49 with gamma spectroscopy and heavy-ion transfer reactions Type Journal Article
Year 2011 Publication Physics Letters B Abbreviated Journal Phys. Lett. B
Volume 697 Issue 4 Pages 288-293
Keywords Multi-nucleon transfer; Gamma spectroscopy; Magnetic spectrometer; Particle-core coupling
Abstract Neutron rich nuclei around Ca-48 have been measured with the CLARA-PRISMA setup, making use of Ca-48 on Ni-64 binary reactions, at 5.9 MeV/A. Angular distributions of gamma rays give evidence, in several transfer channels, for a large spin alignment (approximate to 70%) perpendicular to the reaction plane, making it possible to firmly establish spin and parities of the excited states. In the case of Ca-49, states arising from different types of particle-core couplings are, for the first time, unambiguously identified on basis of angular distribution, polarization and lifetime measurements. Shell model and particle-vibration coupling calculations are used to pin down the nature of the states. Evidence is found for the presence, in the same excitation energy region, of two types of coupled states, i.e. single particle coupled to either Ca-48 or Ca-50 simple configurations, and particle-vibration coupled states based on the 3- phonon of Ca-48.
Address (down) [Montanari, D.; Leoni, S.; Bocchi, G.; Bortignon, P. F.; Bracco, A.; Camera, F.; Colo, G.; Corsi, A.; Crespi, F. C. L.; Nicolini, R.] Univ Milan, Dipartimento Fis, Milan, Italy, Email: silvia.leoni@mi.infn.it
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0370-2693 ISBN Medium
Area Expedition Conference
Notes ISI:000288300400005 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 542
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