Abstract: Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application.

Abstract: Following the completion of the second neutron beam line and the related experimental area (EAR2) at the n_TOF spallation neutron source at CERN, several experiments were planned and performed. The high instantaneous neutron flux available in EAR2 allows to investigate neutron induced reactions with charged particles in the exit channel even employing targets made out of small amounts of short-lived radioactive isotopes. After the successful measurement of the Be-7(n,alpha)alpha cross section, the Be-7(n,p)Li-7 reaction was studied in order to provide still missing cross section data of relevance for Big Bang Nucleosynthesis (BBN), in an attempt to find a solution to the cosmological Lithium abundance problem. This paper describes the experimental setup employed in such a measurement and its characterization.

Abstract: In current particle physics experiments, silicon strip detectors are widely used as part of the inner tracking layers. A foreseeable large-scale application for such detectors consists of the luminosity upgrade of the Large Hadron Collider (LHC), the super-LHC or sLHC, where silicon detectors with extreme radiation hardness are required. The mission statement of the CERN RD50 Collaboration is the development of radiation-hard semiconductor devices for very high luminosity colliders. As a consequence, the aim of the R&D programme presented in this article is to develop silicon particle detectors able to operate at sLHC conditions. Research has progressed in different areas, such as defect characterisation, defect engineering and full detector systems. Recent results from these areas will be presented. This includes in particular an improved understanding of the macroscopic changes of the effective doping concentration based on identification of the individual microscopic defects, results from irradiation with a mix of different particle types as expected for the sLHC, and the observation of charge multiplication effects in heavily irradiated detectors at very high bias voltages.

Abstract: We consider an extension of the Standard Model with two singlet leptons, with masses in the electroweak range, that induce neutrino masses via the see-saw mechanism, plus a generic new physics sector at a higher scale, A. We apply the minimal flavor violation (MFV) principle to the corresponding Effective Field Theory (nu SMEFT) valid at energy scales E << A. We identify the irreducible sources of lepton flavor and lepton number violation at the renormalizable level, and apply the MFV ansatz to derive the scaling of the Wilson coefficients of the nu SMEFT operators up to dimension six. We highlight the most important phenomenological consequences of this hypothesis in the rates for exotic Higgs decays, the decay length of the heavy neutrinos, and their production modes at present and future colliders. We also comment on possible astrophysical implications.

Abstract: In this work, we explore the flavor-changing decays H-i -> bs in a general supersymmetric scenario. In these models the flavor-changing decays arise at loop level, but-because they originate from a dimension-four operator-they do not decouple and may provide a first sign of new physics for heavy masses beyond the reach of colliders. In the framework of the minimal supersymmetric extension of the Standard Model, we find that the largest branching ratio of the lightest Higgs (H-1) is O(10(-6)) after imposing present experimental constraints, while heavy Higgs states may still present branching ratios O(10(-3)). In a more general supersymmetric scenario, where additional Higgs states may modify the Higgs mixings, the branching ratio BR(H-1 -> bs) can reach values O(10(-4)), while heavy Higgses still remain at O(10(-3)). Although these values are clearly out of reach for the LHC, a full study in a linear collider environment could be worth pursuing.