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Author Rodriguez-Alvarez, M.J.; Sanchez, F.; Soriano, A.; Iborra, A. doi  openurl
  Title Sparse Givens resolution of large system of linear equations: Applications to image reconstruction Type Journal Article
  Year 2010 Publication Mathematical and Computer Modelling Abbreviated Journal Math. Comput. Model.  
  Volume 52 Issue 7-8 Pages 1258-1264  
  Keywords Givens rotations; QR-factorization; Computed tomography; Image reconstruction  
  Abstract In medicine, computed tomographic images are reconstructed from a large number of measurements of X-ray transmission through the patient (projection data). The mathematical model used to describe a computed tomography device is a large system of linear equations of the form AX = B. In this paper we propose the QR decomposition as a direct method to solve the linear system. QR decomposition can be a large computational procedure. However, once it has been calculated for a specific system, matrices Q and R are stored and used for any acquired projection on that system. Implementation of the QR decomposition in order to take more advantage of the sparsity of the system matrix is discussed.  
  Address (up) [Rodriguez-Alvarez, Maria-Jose; Iborra, Amadeo] Univ Politecn Valencia, Inst Matemat Multidisciplinar, E-46022 Valencia, Spain, Email: mjrodri@imm.upv.es  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0895-7177 ISBN Medium  
  Area Expedition Conference  
  Notes ISI:000280933700043 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ elepoucu @ Serial 395  
Permanent link to this record
 

 
Author Ros Garcia, A.; Barrio, J.; Etxebeste, A.; Garcia-Lopez, J.; Jimenez-Ramos, M.C.; Lacasta, C.; Muñoz, E.; Oliver, J.F.; Roser, J.; Llosa, G. doi  openurl
  Title MACACO II test-beam with high energy photons Type Journal Article
  Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 65 Issue 24 Pages 245027 - 12pp  
  Keywords Compton imaging; Compton camera; proton therapy; LaBr3; test-beam; image reconstruction  
  Abstract The IRIS group at IFIC Valencia is developing a three-layer Compton camera for treatment monitoring in proton therapy. The system is composed of three detector planes, each made of a LaBr3<i monolithic crystal coupled to a SiPM array. Having obtained successful results with the first prototype (MACACO) that demonstrated the feasibility of the proposed technology, a second prototype (MACACO II) with improved performance has been developed, and is the subject of this work. The new system has an enhanced detector energy resolution which translates into a higher spatial resolution of the telescope. The image reconstruction method has also been improved with an accurate model of the sensitivity matrix. The device has been tested with high energy photons at the National Accelerator Centre (CNA, Seville). The tests involved a proton beam of 18 MeV impinging on a graphite target, to produce 4.4 MeV photons. Data were taken at different system positions of the telescope with the first detector at 65 and 160 mm from the target, and at different beam intensities. The measurements allowed successful reconstruction of the photon emission distribution at two target positions separated by 5 mm in different telescope configurations. This result was obtained both with data recorded in the first and second telescope planes (two interaction events) and, for the first time in beam experiments, with data recorded in the three planes (three interaction events).  
  Address (up) [Ros Garcia, A.; Barrio, J.; Etxebeste, A.; Lacasta, C.; Munoz, E.; Oliver, J. F.; Roser, J.; Llosa, G.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: arosgar@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000600803000001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 4654  
Permanent link to this record
 

 
Author Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G. doi  openurl
  Title Joint image reconstruction algorithm in Compton cameras Type Journal Article
  Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 67 Issue 15 Pages 155009 - 15pp  
  Keywords Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope  
  Abstract Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging.  
  Address (up) [Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000827830200001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5298  
Permanent link to this record
 

 
Author Roser, J.; Muñoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J.F. doi  openurl
  Title Image reconstruction for a multi-layer Compton telescope: an analytical model for three interaction events Type Journal Article
  Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 65 Issue 14 Pages 145005 - 17pp  
  Keywords Compton camera; Compton imaging; hadron therapy; image reconstruction; lm-mlem; monte carlo simulations; multi-layer Compton telescope  
  Abstract Compton Cameras are electronically collimated photon imagers suitable for sub-MeV to few MeV gamma-ray detection. Such features are desirable to enablein vivorange verification in hadron therapy, through the detection of secondary Prompt Gammas. A major concern with this technique is the poor image quality obtained when the incoming gamma-ray energy is unknown. Compton Cameras with more than two detector planes (multi-layer Compton Cameras) have been proposed as a solution, given that these devices incorporate more signal sequences of interactions to the conventional two interaction events. In particular, three interaction events convey more spectral information as they allow inferring directly the incident gamma-ray energy. A three-layer Compton Telescope based on continuous Lanthanum (III) Bromide crystals coupled to Silicon Photomultipliers is being developed at the IRIS group of IFIC-Valencia. In a previous work we proposed a spectral reconstruction algorithm for two interaction events based on an analytical model for the formation of the signal. To fully exploit the capabilities of our prototype, we present here an extension of the model for three interaction events. Analytical expressions of the sensitivity and the System Matrix are derived and validated against Monte Carlo simulations. Implemented in a List Mode Maximum Likelihood Expectation Maximization algorithm, the proposed model allows us to obtain four-dimensional (energy and position) images by using exclusively three interaction events. We are able to recover the correct spectrum and spatial distribution of gamma-ray sources when ideal data are employed. However, the uncertainties associated to experimental measurements result in a degradation when real data from complex structures are employed. Incorrect estimation of the incident gamma-ray interaction positions, and missing deposited energy associated with escaping secondaries, have been identified as the causes of such degradation by means of a detailed Monte Carlo study. As expected, our current experimental resolution and efficiency to three interaction events prevents us from correctly recovering complex structures of radioactive sources. However, given the better spectral information conveyed by three interaction events, we expect an improvement of the image quality of conventional Compton imaging when including such events. In this regard, future development includes the incorporation of the model assessed in this work to the two interaction events model in order to allow using simultaneously two and three interaction events in the image reconstruction.  
  Address (up) [Roser, J.; Munoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J. F.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: Jorge.Roser@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000552701600001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 4481  
Permanent link to this record
 

 
Author NEXT Collaboration (Simon, A. et al); Gomez-Cadenas, J. J.; Alvarez, V.; Benlloch-Rodriguez, J. M.; Botas, A.; Carcel, S.; Carrion, J.V.; Diaz, J.; Felkai, R.; Ferrario, P.; Laing, A.; Liubarsky, I.; Lopez-March, N.; Martin-Albo, J.; Martinez, A.; Muñoz Vidal, J.; Musti, M.; Nebot-Guinot, M.; Novella, P.; Palmeiro, B.; Perez, J.; Querol, M.; Renner, J.; Rodriguez, J.; Sorel, M.; Torrent, J.; Yahlali, N. url  doi
openurl 
  Title Application and performance of an ML-EM algorithm in NEXT Type Journal Article
  Year 2017 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 12 Issue Pages P08009 - 22pp  
  Keywords Gaseous imaging and tracking detectors; Image reconstruction in medical imaging; Time projection Chambers (TPC); Medical-image reconstruction methods and algorithms; computer-aided software  
  Abstract The goal of the NEXT experiment is the observation of neutrinoless double beta decay in Xe-136 using a gaseous xenon TPC with electroluminescent amplification and specialized photodetector arrays for calorimetry and tracking. The NEXT Collaboration is exploring a number of reconstruction algorithms to exploit the full potential of the detector. This paper describes one of them: the Maximum Likelihood Expectation Maximization (ML-EM) method, a generic iterative algorithm to find maximum-likelihood estimates of parameters that has been applied to solve many different types of complex inverse problems. In particular, we discuss a bi-dimensional version of the method in which the photosensor signals integrated over time are used to reconstruct a transverse projection of the event. First results show that, when applied to detector simulation data, the algorithm achieves nearly optimal energy resolution (better than 0.5% FWHM at the Q value of 136Xe) for events distributed over the full active volume of the TPC.  
  Address (up) [Simon, A.; Gomez-Cadenas, J. J.; Alvarez, V.; Benlloch-Rodriguez, J. M.; Botas, A.; Carcel, S.; Carrion, J. V.; Diaz, J.; Felkai, R.; Ferrario, P.; Laing, A.; Liubarsky, I.; Lopez-March, N.; Martin-Albo, J.; Martinez, A.; Munoz Vidal, J.; Musti, M.; Nebot-Guinot, M.; Novella, P.; Palmeiro, B.; Perez, J.; Querol, M.; Renner, J.; Rodriguez, J.; Sorel, M.; Torrent, J.; Yahlali, N.] CSIC, Inst Fis Corpuscular IFIC, Calle Catedrat Jose Beltran 2, Valencia 46980, Spain, Email: ander.simon@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000414159500009 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 3358  
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