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Author Llosa, G.; Barrio, J.; Lacasta, C.; Callier, S.; Raux, L.; de La Taille, C.
Title First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy Type Journal Article
Year 2011 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 648 Issue Pages S96-S99
Keywords Hadron therapy; Compton imaging; LaBr3; Continuous crystal; SiPM; MPPC; G-APD
Abstract A detector head composed of a continuous LaBr3 crystal coupled to a silicon photomultiplier array has been mounted and tested, for its use in a Compton telescope for dose monitoring in hadron therapy. The LaBr3 crystal has 16 mm x 18 mm x 5 mm size, and it is surrounded with reflecting material in five faces. The SiPM array has 16 (4 x 4) elements of 3 mm x 3 mm size. The SPIROC1 ASIC has been employed as readout electronics. The detector shows a linear behavior up to 1275 keV. The energy resolution obtained at 511 keV is 7% FWHM, and it varies as one over the square root of the energy up to the energies tested. The variations among the detector channels are within 12%. A preliminary measurement of the timing resolution gives 7 ns FWHM. The spatial resolution obtained with the center of gravity method is 1.2 mm FWHM. The tests performed confirm the correct functioning of the detector.
Address (up) [Llosa, G.; Barrio, J.; Lacasta, C.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: gabriela.llosa@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000305376900026 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1068
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Author Llosa, G.; Trovato, M.; Barrio, J.; Etxebeste, A.; Muñoz, E.; Lacasta, C.; Oliver, J.F.; Rafecas, M.; Solaz, C.; Solevi, P.
Title First Images of a Three-layer compton Telescope prototype for Treatment Monitoring in hadron Therapy Type Journal Article
Year 2016 Publication Frontiers in Oncology Abbreviated Journal Front. Oncol.
Volume 6 Issue Pages 14 - 6pp
Keywords Compton camera; Compton telescope; hadron therapy; treatment monitoring; LaBr3
Abstract A Compton telescope for dose monitoring in hadron therapy is under development at IFIC. The system consists of three layers of LaBr3 crystals coupled to silicon photomulti-plier arrays. Na-22 sources have been successfully imaged reconstructing the data with an ML-EM code. Calibration and temperature stabilization are necessary for the prototype operation at low coincidence rates. A spatial resolution of 7.8 mm FWHM has been obtained in the first imaging tests.
Address (up) [Llosa, Gabriela; Trovato, Marco; Barrio, John; Etxebeste, Ane; Munoz, Enrique; Lacasta, Carlos; Oliver, Josep F.; Rafecas, Magdalena; Solaz, Carles; Solevi, Paola] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: gabriela.llosa@ific.uv.es
Corporate Author Thesis
Publisher Frontiers Media Sa Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2234-943x ISBN Medium
Area Expedition Conference
Notes WOS:000369799800001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ elepoucu @ Serial 2785
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Author Lobo, F.S.N.; Olmo, G.J.; Rubiera-Garcia, D.
Title Semiclassical geons as solitonic black hole remnants Type Journal Article
Year 2013 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 07 Issue 7 Pages 011 - 10pp
Keywords modified gravity; primordial black holes; Wormholes; quantum field theory on curved space
Abstract We find that the end state of black hole evaporation could be represented by non-singular and without event horizon stable solitonic remnants with masses of the order the Planck scale and up to similar to 16 units of charge. Though these objects are locally indistinguishable from spherically symmetric, massive electric (or magnetic) charges, they turn out to be sourceless geons containing a wormhole generated by the electromagnetic field. Our results are obtained by interpreting semiclassical corrections to Einstein's theory in the first-order (Palatini) formalism, which yields second-order equations and avoids the instabilities of the usual (metric) formulation of quadratic gravity. We also discuss the potential relevance of these solutions for primordial black holes and the dark matter problem.
Address (up) [Lobo, Francisco S. N.] Univ Lisbon, Ctr Astron & Astrofis, P-1749016 Lisbon, Portugal, Email: flobo@cii.fc.ul.pt;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000322582000012 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1532
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Author Lopez Honorez, L.; Reid, B.A.; Mena, O.; Verde, L.; Jimenez, R.
Title Coupled dark matter-dark energy in light of near universe observations Type Journal Article
Year 2010 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 09 Issue 9 Pages 029 - 36pp
Keywords dark energy experiments; dark energy theory; cosmological parameters from LSS
Abstract Cosmological analysis based on currently available observations are unable to rule out a sizeable coupling among the dark energy and dark matter fluids. We explore a variety of coupled dark matter-dark energy models, which satisfy cosmic microwave background constraints, in light of low redshift and near universe observations. We illustrate the phenomenology of different classes of dark coupling models, paying particular attention in distinguishing between effects that appear only on the expansion history and those that appear in the growth of structure. We find that while a broad class of dark coupling models are effectively models where general relativity (GR) is modified – and thus can be probed by a combination of tests for the expansion history and the growth of structure -, there is a class of dark coupling models where gravity is still GR, but the growth of perturbations is, in principle modified. While this effect is small in the specific models we have considered, one should bear in mind that an inconsistency between reconstructed expansion history and growth may not uniquely indicate deviations from GR. Our low redshift constraints arise from cosmic velocities, redshift space distortions and dark matter abundance in galaxy voids. We find that current data constrain the dimensionless coupling to be vertical bar xi vertical bar < 0.2, but prospects from forthcoming data are for a significant improvement. Future, precise measurements of the Hubble constant, combined with high-precision constraints on the growth of structure, could provide the key to rule out dark coupling models which survive other tests. We shall exploit as well weak equivalence principle violation arguments, which have the potential to highly disfavour a broad family of coupled models.
Address (up) [Lopez Honorez, Laura] UAM, CSIC, Dept Phys, Madrid 28049, Spain, Email: laura.lopez@uam.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes ISI:000283576500007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 343
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Author Lopez-Fogliani, D.E.; Perez, A.D.; Ruiz de Austri, R.
Title Dark matter candidates in the NMSSM with RH neutrino superfields Type Journal Article
Year 2021 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 04 Issue 4 Pages 067 - 35pp
Keywords dark matter theory; dark matter detectors
Abstract R-parity conserving supersymmetric models with right-handed (RH) neutrinos are very appealing since they could naturally explain neutrino physics and also provide a good dark matter (DM) candidate such as the lightest supersymmetric particle (LSP). In this work we consider the next-to-minimal supersymmetric standard model (NMSSM) plus RH neutrino superfields, with effective Majorana masses dynamically generated at the electroweak scale (EW). We perform a scan of the relevant parameter space and study both possible DM candidates: RH sneutrino and neutralino. Especially for the case of RH sneutrino DM we analyse the intimate relation between both candidates to obtain the correct amount of relic density. Besides the well-known resonances, annihilations through scalar quartic couplings and coannihilation mechanisms with all kind of neutralinos, are crucial. Finally, we present the impact of current and future direct and indirect detection experiments on both DM candidates.
Address (up) [Lopez-Fogliani, Daniel E.] Univ Buenos Aires, Fac Ciencia Exactas & Nat, Inst Fis Buenos Aires UBA, RA-1428 Buenos Aires, DF, Argentina, Email: daniel.lopez@df.uba.ar;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000644501000049 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4824
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Author Lopez-Honorez, L.; Mena, O.; Palomares-Ruiz, S.; Villanueva-Domingo, P.; Witte, S.J.
Title Variations in fundamental constants at the cosmic dawn Type Journal Article
Year 2020 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 06 Issue 6 Pages 026 - 25pp
Keywords cosmology of theories beyond the SM; particle physics – cosmology connection; reionization
Abstract The observation of space-time variations in fundamental constants would provide strong evidence for the existence of new light degrees of freedom in the theory of Nature. Robustly constraining such scenarios requires exploiting observations that span different scales and probe the state of the Universe at different epochs. In the context of cosmology, both the cosmic microwave background and the Lyman-a forest have proven to be powerful tools capable of constraining variations in electromagnetism, however at the moment there do not exist cosmological probes capable of bridging the gap between recombination and reionization. In the near future, radio telescopes will attempt to measure the 21 cm transition of neutral hydrogen during the epochs of reionization and the cosmic dawn (and potentially the tail end of the dark ages); being inherently sensitive to electromagnetic phenomena, these experiments will offer a unique perspective on space-time variations of the fine-structure constant and the electron mass. We show here that large variations in these fundamental constants would produce features on the 21 cm power spectrum that may be distinguishable from astrophysical uncertainties. Furthermore, we forecast the sensitivity for the Square Kilometer Array, and show that the 21 cm power spectrum may be able to constrain variations at the level of O(10(-3)).
Address (up) [Lopez-Honorez, Laura] Univ Libre Bruxelles, Serv Phys Theor, CP225, B-1050 Brussels, Belgium, Email: llopezho@ulb.ac.be;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000551875400049 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4473
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Author Lopez-Honorez, L.; Mena, O.; Palomares-Ruiz, S.; Vincent, A.C.
Title Constraints on dark matter annihilation from CMB observations before Planck Type Journal Article
Year 2013 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 07 Issue 7 Pages 046 - 26pp
Keywords dark matter theory; CMBR theory
Abstract We compute the bounds on the dark matter (DM) annihilation cross section using the most recent Cosmic Microwave Background measurements from WMAP9, SPT'11 and ACT'10. We consider DM with mass in the MeV-TeV range annihilating 100% into either an e(+)e(-) or a mu(+)mu(-) pair. We consider a realistic energy deposition model, which includes the dependence on the redshift, DM mass and annihilation channel. We exclude the canonical thermal relic abundance cross section (<sigma nu > = 3 x 10(-26) cm(3)s(-1)) for DM masses below 30 GeV and 15 GeV for the e(+)e(-) and mu(+)mu(-) channels, respectively. A priori, DM annihilating in halos could also modify the reionization history of the Universe at late times. We implement a realistic halo model taken from results of state-of-the-art N-body simulations and consider a mixed reionization mechanism, consisting on reionization from DM as well as from first stars. We find that the constraints on DM annihilation remain unchanged, even when large uncertainties on the halo model parameters are considered.
Address (up) [Lopez-Honorez, Laura] Vrije Univ Brussel, B-1050 Brussels, Belgium, Email: llopezho@vub.ac.be;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000322582000047 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1533
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Author Lopez-Honorez, L.; Mena, O.; Moline, A.; Palomares-Ruiz, S.; Vincent, A.C.
Title The 21 cm signal and the interplay between dark matter annihilations and astrophysical processes Type Journal Article
Year 2016 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 08 Issue 8 Pages 004 - 40pp
Keywords dark matter theory; intergalactic media; reionization
Abstract Future dedicated radio interferometers, including HERA and SKA, are very promising tools that aim to study the epoch of reionization and beyond via measurements of the 21 cm signal from neutral hydrogen. Dark matter (DM) annihilations into charged particles change the thermal history of the Universe and, as a consequence, affect the 21 cm signal. Accurately predicting the effect of DM strongly relies on the modeling of annihilations inside halos. In this work, we use up-to-date computations of the energy deposition rates by the products from DM annihilations, a proper treatment of the contribution from DM annihilations in halos, as well as values of the annihilation cross section allowed by the most recent cosmological measurements from the Planck satellite. Given current uncertainties on the description of the astrophysical processes driving the epochs of reionization, X-ray heating and Lyman-alpha pumping, we find that disentangling DM signatures from purely astrophysical effects, related to early-time star formation processes or late-time galaxy X-ray emissions, will be a challenging task. We conclude that only annihilations of DM particles with masses of similar to 100 MeV, could leave an unambiguous imprint on the 21 cm signal and, in particular, on the 21cm power spectrum. This is in contrast to previous, more optimistic results in the literature, which have claimed that strong signatures might also be present even for much higher DM masses. Additional measurements of the 21cm signal at different cosmic epochs will be crucial in order to break the strong parameter degeneracies between DM annihilations and astrophysical effects and undoubtedly single out a DM imprint for masses different from similar to 100 MeV.
Address (up) [Lopez-Honorez, Laura] Vrije Univ Brussel, Theoret Natuurkunde, Pl Laan 2, B-1050 Brussels, Belgium, Email: llopezho@vub.ac.be;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000389859100050 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 2899
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Author Lopez-Ibañez, M.L.; Melis, A.; Jay Perez, M.; Vives, O.
Title Slepton non-universality in the flavor-effective MSSM Type Journal Article
Year 2017 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 11 Issue 11 Pages 162 - 27pp
Keywords Quark Masses and SM Parameters; Supersymmetric Standard Model; Super-symmetry Breaking; Supersymmetric Effective Theories
Abstract Supersymmetric theories supplemented by an underlying flavor-symmetry G(f) provide a rich playground for model building aimed at explaining the flavor structure of the Standard Model. In the case where supersymmetry breaking is mediated by gravity, the soft-breaking Lagrangian typically exhibits large tree-level flavor violating e ff ects, even if it stems from an ultraviolet flavor-conserving origin. Building on previous work, we continue our phenomenological analysis of these models with a particular emphasis on leptonicflavor observables. We consider three representative models which aim to explain the flavor structure of the lepton sector, with symmetry groups G(f) = Delta (27), A(4); and S-3.
Address (up) [Luisa Lopez-Ibanez, M.; Melis, Aurora; Jay Perez, M.; Vives, Oscar] Univ Valencia, Dept Fis Teor, Dr Moliner 50, Burjassot, Valencia, Spain, Email: m.luisa.lopez-ibanez@uv.es;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000416356500006 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3382
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Author Ma, Y.Z.; Vijande, J.; Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.; Chamberland, M.J.P.; Thomson, R.M.; Verhaegen, F.; Beaulieu, L.
Title A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy Type Journal Article
Year 2017 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume 44 Issue 11 Pages 5961-5976
Keywords Ir-192; HDR brachytherapy; model based dose calculation; Monte Carlo methods; shielded applicator; TG-186
Abstract PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy.
Address (up) [Ma, Yunzhi; Beaulieu, Luc] CHU Quebec, Dept Radio Oncol & Axe Oncol, Ctr Rech, Quebec City, PQ G1R 2J6, Canada, Email: yunzhi.Ma@crchuq.ulaval.ca
Corporate Author Thesis
Publisher Wiley Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes WOS:000414970800039 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3370
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