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Perez-Calatayud, J., Ballester, F., Tedgren, C., DeWerd, L. A., Papagiannis, P., Rivard, M. J., et al. (2022). GEC-ESTRO ACROP recommendations on calibration and traceability of HE HDR-PDR photon-emitting brachytherapy sources at the hospital level. Radiother. Oncol., 176, 108–117.
Abstract: The vast majority of radiotherapy departments in Europe using brachytherapy (BT) perform temporary implants of high-or pulsed-dose rate (HDR-PDR) sources with photon energies higher than 50 keV. Such techniques are successfully applied to diverse pathologies and clinical scenarios. These recommen-dations are the result of Working Package 21 (WP-21) initiated within the BRAchytherapy PHYsics Quality Assurance System (BRAPHYQS) GEC-ESTRO working group with a focus on HDR-PDR source cal-ibration. They provide guidance on the calibration of such sources, including practical aspects and issues not specifically accounted for in well-accepted societal recommendations, complementing the BRAPHYQS WP-18 Report dedicated to low energy BT photon emitting sources (seeds). The aim of this report is to provide a European-wide standard in HDR-PDR BT source calibration at the hospital level to maintain high quality patient treatments.
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Fileviez Perez, P., & Murgui, C. (2019). Gamma lines from the hidden sector. Phys. Rev. D, 100(12), 123007–11pp.
Abstract: We discuss the visibility of gamma lines from dark matter annihilation. We point out a class of theories for dark matter which predict the existence of gamma lines with striking features. In these theories, the final state radiation processes are highly suppressed and one could distinguish easily the gamma lines from the continuum spectrum. We discuss the main experimental bounds and show that one could test the predictions for gamma lines in the near future in the context of simple gauge theories for dark matter.
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Fileviez Perez, P., Iminniyaz, H., Rodrigo, G., & Spinner, S. (2010). Gauge mediated supersymmetry breaking via seesaw mechanisms. Phys. Rev. D, 81(9), 095013–12pp.
Abstract: We present a simple scenario for gauge mediated supersymmetry breaking (GMSB) where the messengers are also the fields that generate neutrino masses. We show that the simplest such scenario corresponds to the case where neutrino masses are generated through the type I and type III seesaw mechanisms. The entire supersymmetric spectrum and Higgs masses are calculable from only four input parameters. Since the electroweak symmetry is broken through a doubly radiative mechanism, meaning a nearly zero B term at the messenger scale which runs down to acceptable values, one obtains quite a constrained spectrum for the supersymmetric particles whose properties we describe. We refer to this mechanism as "nu GMSB.''
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Fileviez Perez, P., Murgui, C., & Plascencia, A. D. (2019). Neutrino-dark matter connections in gauge theories. Phys. Rev. D, 100(3), 035041–14pp.
Abstract: We discuss the connection between the origin of neutrino masses and the properties of dark matter candidates in the context of gauge extensions of the Standard Model. We investigate minimal gauge theories for neutrino masses where the neutrinos arc predicted to be Dirac or Majorana fermions. We find that the upper bound on the effective number of relativistic species provides a strong constraint in the scenarios with Dirac neutrinos. In the context of theories where the lepton number is a local gauge symmetry spontaneously broken at the low scale, the existence of dark matter is predicted from the condition of anomaly cancellation. Applying the cosmological bound on the dark matter relic density, we find an upper bound on the symmetry breaking scale in the multi-TeV region. These results imply that we could test simple gauge theories for neutrino masses at current or future experiments.
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Fileviez Perez, P., Murgui, C., & Plascencia, A. D. (2019). The QCD axion and unification. J. High Energy Phys., 11(11), 093–21pp.
Abstract: The QCD axion is one of the most appealing candidates for the dark matter in the Universe. In this article, we discuss the possibility to predict the axion mass in the context of a simple renormalizable grand unified theory where the Peccei-Quinn scale is determined by the unification scale. In this framework, the axion mass is predicted to be in the range ma, <^> (3-13) x 10-9 eV. We study the axion phenomenology and find that the ABRACADABRA and CASPEr-Electric experiments will be able to fully probe this mass window.
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Fileviez Perez, P., Golias, E., Murgui, C., & Plascencia, A. D. (2020). The Higgs and leptophobic force at the LHC. J. High Energy Phys., 07(7), 087–19pp.
Abstract: The Higgs boson could provide the key to discover new physics at the Large Hadron Collider. We investigate novel decays of the Standard Model (SM) Higgs boson into leptophobic gauge bosons which can be light in agreement with all experimental constraints. We study the associated production of the SM Higgs and the leptophobic gauge boson that could be crucial to test the existence of a leptophobic force. Our results demonstrate that it is possible to have a simple gauge extension of the SM at the low scale, without assuming very small couplings and in agreement with all the experimental bounds that can be probed at the LHC.
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Fileviez Perez, P., Golias, E., Li, R. H., & Murgui, C. (2019). Leptophobic dark matter and the baryon number violation scale. Phys. Rev. D, 99(3), 035009–16pp.
Abstract: We discuss the possible connection between the scale for baryon number violation and the cosmological bound on the dark matter relic density. A simple gauge theory for baryon number which predicts the existence of a leptophobic cold dark matter particle candidate is investigated. In this context, the dark matter candidate is a Dirac fermion with mass defined by the new symmetry breaking scale. Using the cosmological bounds on the dark matter relic density we find the upper bound on the symmetry breaking scale around 200 TeV. The properties of the leptophobic dark matter candidate are investigated in great detail and we show the prospects to test this theory at current and future experiments. We discuss the main implications for the mechanisms to explain the matter and antimatter asymmetry in the Universe.
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Magan, D. L. P., Caballero, L., Domingo-Pardo, C., Agramunt-Ros, J., Albiol, F., Casanovas, A., et al. (2016). First tests of the applicability of gamma-ray imaging for background discrimination in time-of-flight neutron capture measurements. Nucl. Instrum. Methods Phys. Res. A, 823, 107–119.
Abstract: In this work we explore for the first time the applicability of using gamma-ray imaging in neutron capture measurements to identify and suppress spatially localized background. For this aim, a pinhole gamma camera is assembled, tested and characterized in terms of energy and spatial performance. It consists of a monolithic CeBr3 scintillating crystal coupled to a position-sensitive photomultiplier and readout through an integrated circuit AMIC2GR. The pinhole collimator is a massive carven block of lead. A series of dedicated measurements with calibrated sources and with a neutron beam incident on a Au-197 sample have been carried out at n_TOF, achieving an enhancement of a factor of two in the signal-to-background ratio when selecting only those events coming from the direction of the sample.
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Peppa, V., Thomson, R. M., Enger, S. A., Fonseca, G. P., Lee, C. N., Lucero, J. N. E., et al. (2023). A MC-based anthropomorphic test case for commissioning model-based dose calculation in interstitial breast 192-Ir HDR brachytherapy. Med. Phys., 50(7), 4675–4687.
Abstract: PurposeTo provide the first clinical test case for commissioning of Ir-192 brachytherapy model-based dose calculation algorithms (MBDCAs) according to the AAPM TG-186 report workflow. Acquisition and Validation MethodsA computational patient phantom model was generated from a clinical multi-catheter Ir-192 HDR breast brachytherapy case. Regions of interest (ROIs) were contoured and digitized on the patient CT images and the model was written to a series of DICOM CT images using MATLAB. The model was imported into two commercial treatment planning systems (TPSs) currently incorporating an MBDCA. Identical treatment plans were prepared using a generic Ir-192 HDR source and the TG-43-based algorithm of each TPS. This was followed by dose to medium in medium calculations using the MBDCA option of each TPS. Monte Carlo (MC) simulation was performed in the model using three different codes and information parsed from the treatment plan exported in DICOM radiation therapy (RT) format. Results were found to agree within statistical uncertainty and the dataset with the lowest uncertainty was assigned as the reference MC dose distribution. Data Format and Usage NotesThe dataset is available online at ,. Files include the treatment plan for each TPS in DICOM RT format, reference MC dose data in RT Dose format, as well as a guide for database users and all files necessary to repeat the MC simulations. Potential ApplicationsThe dataset facilitates the commissioning of brachytherapy MBDCAs using TPS embedded tools and establishes a methodology for the development of future clinical test cases. It is also useful to non-MBDCA adopters for intercomparing MBDCAs and exploring their benefits and limitations, as well as to brachytherapy researchers in need of a dosimetric and/or a DICOM RT information parsing benchmark. Limitations include specificity in terms of radionuclide, source model, clinical scenario, and MBDCA version used for its preparation.
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Peñuelas, A., & Pich, A. (2017). Flavour alignment in multi-Higgs-doublet models. J. High Energy Phys., 12(12), 084–34pp.
Abstract: Extended electroweak scalar sectors containing several doublet multiplets require flavour-aligned Yukawa matrices to prevent the appearance at tree level of unwanted flavour-changing neutral-current transitions. We analyse the misalignment induced by one-loop quantum corrections and explore possible generalizations of the alignment condition and their compatibility with current experimental constraints. The hypothesis of flavour alignment at a high scale turns out to be consistent with all known phenomenological tests.
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