Abstract: Whole-body Positron Emission Tomography (PET) scanners are required in order to span large Fields of View (FOV). Therefore, reaching the sensitivity and spatial resolution required for early stage breast tumor detection is not straightforward. MAMMI is a dedicated breast PET scanner with a ring geometry designed to provide PET images with a spatial resolution as high as 1.5 mm, being able to detect small breast tumors ( < 1 cm). The patient lays down in prone position during the scan, thus making possible to image the whole breast, up to regions close to the base of the pectoral without the requirement of breast compression. Attenuation correction (AC) for PET data improves the image quality and the quantitative accuracy of radioactivity distribution determination. In dedicated, high resolution breast cancer scanners, this correction would enhance the proper diagnosis in early disease stages. In whole-body PET scanners, AC is usually taken into account with the use of transmission scans, either by external radioactive rod sources or by Computed Tomography (CT). This considerably increases the radiation dose administered to the patient and time needed for the exploration. In this work we propose a method for breast shape identification by means of PET image segmentation. The breast shape identification will be used for the determination of the AC. For the case of a specific breast PET scanner the procedure we propose should provide AC similar to that obtained by transmission scans as we take advantage of the breast anatomical simplicity. Experimental validation of the proposed approach with a dedicated breast PET prototype is also presented. The main advantage of this method is an important dose reduction since the transmission scan is not required.

Abstract: We generate new standard solar models using newly analyzed nuclear fusion cross sections and present results for helioseismic quantities and solar neutrino fluxes. The status of the solar abundance problem is discussed. We investigate whether nonstandard solar models with accretion from the protoplanetary disk might alleviate this problem. We examine a broad range of models, analyzing metal-enriched and metal-depleted accretion and three scenarios for the timing of accretion. Only partial solutions are found. Formetal-rich accreted material (Z(ac) greater than or similar to 0.018) there exist combinations of accreted mass and metallicity that bring the depth of the convective zone into agreement with the helioseismic value. For the surface helium abundance, the helioseismic value is reproduced if metal-poor or metal-free accretion is assumed (Z(ac) less than or similar to 0.09). In both cases a few percent of the solar mass must be accreted. Precise values depend on when accretion takes place. We do not find a simultaneous solution to both problems but speculate that changing the hydrogen-to-helium mass ratio in the accreted material may lead to more satisfactory solutions. We also show that, with current data, solar neutrinos are already a very competitive source of information about the solar core and can help constraining possible accretion histories. Even without helioseismic constraints, solar neutrinos rule out the possibility that more than 0.02 M(circle dot) from the protoplanetary disk were accreted after the Sun settled on the main sequence. Finally, we discuss how measurements of neutrinos from the CN cycle could shed light on the interaction between the early Sun and its protoplanetary disk.

Abstract: We present the results of a global neutrino oscillation data analysis within the three-flavour framework. We include the latest results from the MINOS long-baseline experiment (including electron neutrino appearance and anti-neutrino data), updating all relevant solar (Super-Kamiokande (SK) II + III), atmospheric (SK I + II + III) and reactor (KamLAND) data. Furthermore, we include a recent re-calculation of the anti-neutrino fluxes emitted from nuclear reactors. These results have important consequences for the analysis of reactor experiments and in particular for the status of the mixing angle theta(13). In our recommended default analysis, we find from the global fit that the hint for nonzero theta(13) remains weak, at 1.8 sigma for both neutrino mass hierarchy schemes. However, we discuss in detail the dependence of these results on assumptions regarding the reactor neutrino analysis.