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Author |
Soriano, A.; Gonzalez, A.; Orero, A.; Moliner, L.; Carles, M.; Sanchez, F.; Benlloch, J.M.; Correcher, C.; Carrilero, V.; Seimetz, M. |
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Title |
Attenuation correction without transmission scan for the MAMMI breast PET |
Type |
Journal Article |
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Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
648 |
Issue |
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Pages |
S75-S78 |
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Keywords |
Breast PET; Attenuation correction |
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Abstract |
Whole-body Positron Emission Tomography (PET) scanners are required in order to span large Fields of View (FOV). Therefore, reaching the sensitivity and spatial resolution required for early stage breast tumor detection is not straightforward. MAMMI is a dedicated breast PET scanner with a ring geometry designed to provide PET images with a spatial resolution as high as 1.5 mm, being able to detect small breast tumors ( < 1 cm). The patient lays down in prone position during the scan, thus making possible to image the whole breast, up to regions close to the base of the pectoral without the requirement of breast compression. Attenuation correction (AC) for PET data improves the image quality and the quantitative accuracy of radioactivity distribution determination. In dedicated, high resolution breast cancer scanners, this correction would enhance the proper diagnosis in early disease stages. In whole-body PET scanners, AC is usually taken into account with the use of transmission scans, either by external radioactive rod sources or by Computed Tomography (CT). This considerably increases the radiation dose administered to the patient and time needed for the exploration. In this work we propose a method for breast shape identification by means of PET image segmentation. The breast shape identification will be used for the determination of the AC. For the case of a specific breast PET scanner the procedure we propose should provide AC similar to that obtained by transmission scans as we take advantage of the breast anatomical simplicity. Experimental validation of the proposed approach with a dedicated breast PET prototype is also presented. The main advantage of this method is an important dose reduction since the transmission scan is not required. |
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Address  |
[Soriano, A.; Orero, A.; Moliner, L.; Carles, M.; Sanchez, F.; Benlloch, J. M.] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Paterna, Spain, Email: soriano@ific.uv.es |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000305376900021 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
1069 |
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Author |
AGATA Collaboration (Soderstrom, P.A. et al); Gadea, A. |
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Title |
Interaction position resolution simulations and in-beam measurements of the AGATA HPGe detectors |
Type |
Journal Article |
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Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
638 |
Issue |
1 |
Pages |
96-109 |
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Keywords |
gamma-ray tracking; AGATA; Monte Carlo simulations; HPGe detectors; Fusion-evaporation reactions |
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Abstract |
The interaction position resolution of the segmented HPGe detectors of an AGATA triple cluster detector has been studied through Monte Carlo simulations and in an in-beam experiment. A new method based on measuring the energy resolution of Doppler-corrected gamma-ray spectra at two different target to detector distances is described. This gives the two-dimensional position resolution in the plane perpendicular to the direction of the emitted gamma-ray. The gamma-ray tracking was used to determine the full energy of the gamma-rays and the first interaction point, which is needed for the Doppler correction. Five different heavy-ion induced fusion-evaporation reactions and a reference reaction were selected for the simulations. The results of the simulations show that the method works very well and gives a systematic deviation of <1 mm in the FVVHM of the interaction position resolution for the gamma-ray energy range from 60 keV to 5 MeV. The method was tested with real data from an in-beam measurement using a (30)5i beam at 64 MeV on a thin C-12 target. Pulse-shape analysis of the digitized detector waveforms and gamma-ray tracking was performed to determine the position of the first interaction point, which was used for the Doppler corrections. Results of the dependency of the interaction position resolution on the gamma-ray energy and on the energy, axial location and type of the first interaction point, are presented. The FVVHM of the interaction position resolution varies roughly linearly as a function of gamma-ray energy from 8.5 mm at 250 key to 4 mm at 1.5 MeV, and has an approximately constant value of about 4 mm in the gamma-ray energy range from 1.5 to 4 MeV. |
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Address |
[Soderstrom, P. -A.; Nyberg, J.; Al-Adili, A.; Atac, A.; Veyssiere, C.] Uppsala Univ, Dept Phys & Astron, SE-75121 Uppsala, Sweden, Email: P-A.Soderstrom@physics.uu.se |
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Publisher |
Elsevier Science Bv |
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English |
Summary Language |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000290082600015 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
619 |
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Author |
Serenelli, A.M.; Haxton, W.C.; Pena-Garay, C. |
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Title |
Solar Models With Accretion. I. Application To The Solar Abundance Problem |
Type |
Journal Article |
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Year |
2011 |
Publication |
Astrophysical Journal |
Abbreviated Journal |
Astrophys. J. |
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Volume |
743 |
Issue |
1 |
Pages |
24 - 20pp |
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Keywords |
accretion, accretion disks; neutrinos; Sun: abundances; Sun: helioseismology; Sun: interior |
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Abstract |
We generate new standard solar models using newly analyzed nuclear fusion cross sections and present results for helioseismic quantities and solar neutrino fluxes. The status of the solar abundance problem is discussed. We investigate whether nonstandard solar models with accretion from the protoplanetary disk might alleviate this problem. We examine a broad range of models, analyzing metal-enriched and metal-depleted accretion and three scenarios for the timing of accretion. Only partial solutions are found. Formetal-rich accreted material (Z(ac) greater than or similar to 0.018) there exist combinations of accreted mass and metallicity that bring the depth of the convective zone into agreement with the helioseismic value. For the surface helium abundance, the helioseismic value is reproduced if metal-poor or metal-free accretion is assumed (Z(ac) less than or similar to 0.09). In both cases a few percent of the solar mass must be accreted. Precise values depend on when accretion takes place. We do not find a simultaneous solution to both problems but speculate that changing the hydrogen-to-helium mass ratio in the accreted material may lead to more satisfactory solutions. We also show that, with current data, solar neutrinos are already a very competitive source of information about the solar core and can help constraining possible accretion histories. Even without helioseismic constraints, solar neutrinos rule out the possibility that more than 0.02 M(circle dot) from the protoplanetary disk were accreted after the Sun settled on the main sequence. Finally, we discuss how measurements of neutrinos from the CN cycle could shed light on the interaction between the early Sun and its protoplanetary disk. |
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Address |
[Serenelli, Aldo M.] Fac Ciencias, CSIC IEEC, Inst Ciencias Espacio, Bellaterra 08193, Spain |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0004-637x |
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Notes |
WOS:000297408300024 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
857 |
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Author |
Schwetz, T.; Tortola, M.; Valle, J.W.F. |
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Title |
Where we are on theta(13): addendum to 'Global neutrino data and recent reactor fluxes: status of three-flavor oscillation parameters' |
Type |
Journal Article |
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Year |
2011 |
Publication |
New Journal of Physics |
Abbreviated Journal |
New J. Phys. |
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Volume |
13 |
Issue |
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Pages |
109401 - 5pp |
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Keywords |
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Abstract |
In this addendum to Schwetz et al (2011 New J. Phys. 13 063004), we consider the recent results from long-baseline nu(mu) -> nu(e) searches at the Tokai to Kamioka (T2K) and Main Injector Neutrino Oscillation Search (MINOS) experiments and investigate their implications for the mixing angle theta(13) and the leptonic Dirac CP phase delta. By combining the 2.5 sigma indication for a nonzero value of theta(13) coming from the T2K data with global neutrino oscillation data, we obtain a significance for theta(13) > 0 of about 3 sigma with best fit points sin(2) theta(13) = 0.013 (0.016) for normal (inverted) neutrino mass ordering. These results depend somewhat on assumptions concerning the analysis of reactor neutrino data. |
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Address |
[Schwetz, T] Max Planck Inst Kernphys, D-69029 Heidelberg, Germany, Email: schwetz@mpi-hd.mpg.de |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1367-2630 |
ISBN |
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Notes |
WOS:000296664700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
801 |
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Author |
Schwetz, T.; Tortola, M.; Valle, J.W.F. |
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Title |
Global neutrino data and recent reactor fluxes: the status of three-flavour oscillation parameters |
Type |
Journal Article |
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Year |
2011 |
Publication |
New Journal of Physics |
Abbreviated Journal |
New J. Phys. |
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Volume |
13 |
Issue |
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Pages |
063004 - 15pp |
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Keywords |
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Abstract |
We present the results of a global neutrino oscillation data analysis within the three-flavour framework. We include the latest results from the MINOS long-baseline experiment (including electron neutrino appearance and anti-neutrino data), updating all relevant solar (Super-Kamiokande (SK) II + III), atmospheric (SK I + II + III) and reactor (KamLAND) data. Furthermore, we include a recent re-calculation of the anti-neutrino fluxes emitted from nuclear reactors. These results have important consequences for the analysis of reactor experiments and in particular for the status of the mixing angle theta(13). In our recommended default analysis, we find from the global fit that the hint for nonzero theta(13) remains weak, at 1.8 sigma for both neutrino mass hierarchy schemes. However, we discuss in detail the dependence of these results on assumptions regarding the reactor neutrino analysis. |
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Address |
[Schwetz, Thomas] Max Planck Inst Kernphys, D-69029 Heidelberg, Germany, Email: schwetz@mpi-hd.mpg.de |
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Corporate Author |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1367-2630 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000292137500004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
666 |
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