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Author Muñoz, E.; Barrio, J.; Bernabeu, J.; Etxebeste, A.; Lacasta, C.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F. doi  openurl
  Title Study and comparison of different sensitivity models for a two-plane Compton camera Type Journal Article
  Year 2018 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 63 Issue 13 Pages 135004 - 19pp  
  Keywords Compton camera imaging; MLEM; Monte Carlo simulations; image quality  
  Abstract Given the strong variations in the sensitivity of Compton cameras for the detection of events originating from different points in the field of view (FoV), sensitivity correction is often necessary in Compton image reconstruction. Several approaches for the calculation of the sensitivity matrix have been proposed in the literature. While most of these models are easily implemented and can be useful in many cases, they usually assume high angular coverage over the scattered photon, which is not the case for our prototype. In this work, we have derived an analytical model that allows us to calculate a detailed sensitivity matrix, which has been compared to other sensitivity models in the literature. Specifically, the proposed model describes the probability of measuring a useful event in a two-plane Compton camera, including the most relevant physical processes involved. The model has been used to obtain an expression for the system and sensitivity matrices for iterative image reconstruction. These matrices have been validated taking Monte Carlo simulations as a reference. In order to study the impact of the sensitivity, images reconstructed with our sensitivity model and with other models have been compared. Images have been reconstructed from several simulated sources, including point-like sources and extended distributions of activity, and also from experimental data measured with Na-22 sources. Results show that our sensitivity model is the best suited for our prototype. Although other models in the literature perform successfully in many scenarios, they are not applicable in all the geometrical configurations of interest for our system. In general, our model allows to effectively recover the intensity of point-like sources at different positions in the FoV and to reconstruct regions of homogeneous activity with minimal variance. Moreover, it can be employed for all Compton camera configurations, including those with low angular coverage over the scatterer.  
  Address (up) [Munoz, Enrique; Barrio, John; Bernabeu, Jose; Etxebeste, Ane; Lacasta, Carlos; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, IFIC, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000436390800004 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 3639  
Permanent link to this record
 

 
Author Muñoz, E.; Barrio, J.; Etxebeste, A.; Ortega, P.G.; Lacasta, C.; Oliver, J.F.; Solaz, C.; Llosa, G. doi  openurl
  Title Performance evaluation of MACACO: a multilayer Compton camera Type Journal Article
  Year 2017 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 62 Issue 18 Pages 7321-7341  
  Keywords Compton imaging; Compton camera; continuous LaBr3 crystal; silicon photomultiplier; hadron therapy  
  Abstract Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm.  
  Address (up) [Munoz, Enrique; Barrio, John; Etxebeste, Ane; Ortega, Pablo G.; Lacasta, Carlos; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000408229900003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 3253  
Permanent link to this record
 

 
Author Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Nacher, E.; Tain, J.L.; Tolosa, A. url  doi
openurl 
  Title On the performance of large monolithic LaCl3(Ce) crystals coupled to pixelated silicon photosensors Type Journal Article
  Year 2018 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 13 Issue Pages P03014 - 17pp  
  Keywords Compton imaging; Detector modelling and simulations I (interaction of radiation with matter interaction of photons with matter interaction of hadrons with matter etc); Gamma detectors (scintillators CZT HPG HgI etc); Instrumentation and methods for time-of-flight (TOF); spectroscopy  
  Abstract We investigate the performance of large area radiation detectors, with high energy-and spatial-resolution, intended for the development of a Total Energy Detector with gamma-ray imaging capability, so-called i-TED. This new development aims for an enhancement in detection sensitivity in time-of-flight neutron capture measurements, versus the commonly used C6D6 liquid scintillation total-energy detectors. In this work, we study in detail the impact of the readout photosensor on the energy response of large area (50 x 50 mm(2)) monolithic LaCl3(Ce) crystals, in particular when replacing a conventional mono-cathode photomultiplier tube by an 8 x 8 pixelated silicon photomultiplier. Using the largest commercially available monolithic SiPM array (25 cm(2)), with a pixel size of 6 x 6 mm(2), we have measured an average energy resolution of 3.92% FWHM at 662 keV for crystal thick-nesses of 10, 20 and 30 mm. The results are confronted with detailed Monte Carlo (MC) calculations, where optical processes and properties have been included for the reliable tracking of the scintillation photons. After the experimental validation of the MC model, we use our MC code to explore the impact of a smaller photosensor segmentation on the energy resolution. Our optical MC simulations predict only a marginal deterioration of the spectroscopic performance for pixels of 3 x 3 mm(2).  
  Address (up) [Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Tain, J. L.; Tolosa, A.] Univ Valencia, CSIC, Inst Fis Corpuscular, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: Luis.Caballero@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000428146300004 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 3542  
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Author Magan, D.L.P.; Caballero, L.; Domingo-Pardo, C.; Agramunt-Ros, J.; Albiol, F.; Casanovas, A.; Gonzalez, A.; Guerrero, C.; Lerendegui-Marco, J.; Tarifeño-Saldivia, A. url  doi
openurl 
  Title First tests of the applicability of gamma-ray imaging for background discrimination in time-of-flight neutron capture measurements Type Journal Article
  Year 2016 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 823 Issue Pages 107-119  
  Keywords Neutron capture cross-sections; gamma-ray imaging; Total energy detectors; Pulse-height weighting technique; Time-of-flight method  
  Abstract In this work we explore for the first time the applicability of using gamma-ray imaging in neutron capture measurements to identify and suppress spatially localized background. For this aim, a pinhole gamma camera is assembled, tested and characterized in terms of energy and spatial performance. It consists of a monolithic CeBr3 scintillating crystal coupled to a position-sensitive photomultiplier and readout through an integrated circuit AMIC2GR. The pinhole collimator is a massive carven block of lead. A series of dedicated measurements with calibrated sources and with a neutron beam incident on a Au-197 sample have been carried out at n_TOF, achieving an enhancement of a factor of two in the signal-to-background ratio when selecting only those events coming from the direction of the sample.  
  Address (up) [Perez Magan, D. L.; Caballero, L.; Domingo-Pardo, C.; Agramunt-Ros, J.; Albiol, F.; Tarifeno-Saldivia, A.] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain, Email: domingo@ific.uv.es  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000374661600015 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 2665  
Permanent link to this record
 

 
Author Rodriguez-Alvarez, M.J.; Sanchez, F.; Soriano, A.; Iborra, A.; Mora, C. doi  openurl
  Title Exploiting symmetries for weight matrix design in CT imaging Type Journal Article
  Year 2011 Publication Mathematical and Computer Modelling Abbreviated Journal Math. Comput. Model.  
  Volume 54 Issue 7-8 Pages 1655-1664  
  Keywords Computerized tomography imaging; Polar grid; System matrix; Rotation symmetries; ART  
  Abstract In this paper we propose several methods of constructing the system matrix (SM) of a Computed Tomography (CT) scanner with two objectives: (1) to construct SMs in the shortest possible time and store them in an ordinary PC without losing quality, (2) to analyze the possible applications of the proposed method to 3D, taking into account SMs' sizes, computing time and reconstructed image quality. In order to build the SM, we propose two new field of view (FOV) pixellation schemes, based on a polar coordinate system (polar grid) by taking advantage of the polar rotation symmetries of CT devices. Comparisons between the SMs proposed are performed using two phantom and a real CT-simulator images. Global error, contrast, noise and homogeneity of the reconstructed images are discussed.  
  Address (up) [Rodriguez-Alvarez, MJ; Iborra, A; Mora, C] Univ Politecn Valencia, Inst Matemat Multidisciplinar, Valencia 46022, Spain, Email: mjrodri@imm.upv.es  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0895-7177 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000293269200007 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ elepoucu @ Serial 708  
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