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Author |
LHCb Collaboration (Aaij, R. et al); Martinez-Vidal, F.; Oyanguren, A.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
Measurement of the properties of the Xi(b)(*0) baryon |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
05 |
Issue |
5 |
Pages |
161 - 19pp |
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Keywords |
Spectroscopy; B physics; Particle and resonance production; Hadron-Hadron scattering (experiments) |
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Abstract |
We perform a search for near-threshold I (b) (0) resonances decaying to I (b) (-) pi (+) in a sample of proton-proton collision data corresponding to an integrated luminosity of 3 fb(-1) collected by the LHCb experiment. We observe one resonant state, with the following properties: m(Xi b*0) – m (Xi b-) – m (pi+) = 15.727 +/- 0.068 (stat) +/- 0.023 (syst) MeV/c2, Gamma(Xi b*0) = 0.90 +/- 0.16 (stat) +/- 0.08 (syst) MeV. This confirms the previous observation by the CMS collaboration. The state is consistent with the J (P) = 3/2(+)aEuro integral I (b) (au 0) resonance expected in the quark model. This is the most precise determination of the mass and the first measurement of the natural width of this state. We have also measured the ratio sigma(pp -> Xi b*0 X)B(Xi b*0 -> Xi b-pi+)/sigma(pp -> Xi b- X) = 0.28 +/- 0.03 (stat.) +/- 0.01 (syst). |
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Address  |
[Bediaga, I.; De Miranda, J. M.; Ferreira Rodrigues, F.; Gomes, A.; Massafferri, A.; Osorio Rodrigues, B.; dos Reis, A. C.; Rodrigues, A. B.] Ctr Brasileiro Pesquisas Fis, Rio De Janeiro, Brazil, Email: Matthew.charles@cern.ch |
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Springer |
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English |
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1029-8479 |
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Expedition |
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Conference |
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Notes |
WOS:000376893000001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2706 |
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Author |
LHCb Collaboration (Aaij, R. et al); Martinez-Vidal, F.; Oyanguren, A.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
Precise measurements of the properties of the B-1(5721)(0,+) and B-2*(5747)(0,+) states and observation of B-+,B-0 pi(-,+) mass structures |
Type |
Journal Article |
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Year |
2015 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
04 |
Issue |
4 |
Pages |
024 - 27pp |
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Keywords |
Spectroscopy; Hadron-Hadron Scattering; QCD; B physics; Flavor physics |
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Abstract |
Invariant mass distributions of B (+) pi (-) and B (0) pi (+) combinations are investigated in order to study excited B mesons. The analysis is based on a data sample corresponding to 3.0 fb(-1) of pp collision data, recorded by the LHCb detector at centre-of-mass energies of 7 and 8 TeV. Precise measurements of the masses and widths of the B (1)(5721)(0,+) and B (2)(5747)(0,+) states are reported. Clear enhancements, particularly prominent at high pion transverse momentum, are seen over background in the mass range 5850-6000 MeV in both B (+) pi (-) and B (0) pi (+) combinations. The structures are consistent with the presence of four excited B mesons, labelled B (J) (5840)(0,+) and B (J) (5960)(0,+), whose masses and widths are obtained under different hypotheses for their quantum numbers. |
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Address |
[Bediaga, I.; De Miranda, J. M.; Ferreira Rodrigues, F.; Gomes, A.; Massafferri, A.; Rodrigues, B. Osorio; dos Reis, A. C.; Rodrigues, A. B.] CBPF, Rio De Janeiro, Brazil, Email: vladimir.gligorov@cern.ch |
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Springer |
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1029-8479 |
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Expedition |
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Conference |
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Notes |
WOS:000353555200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2217 |
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Author |
LHCb Collaboration (Aaij, R. et al); Garcia Martin, L.M.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
Study of the D(0)p amplitude in Lambda(0)(b) -> D(0)p pi(-) decays |
Type |
Journal Article |
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Year |
2017 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
05 |
Issue |
5 |
Pages |
030 - 43pp |
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Keywords |
B physics; Charm physics; Hadron-Hadron scattering (experiments); QCD; Spectroscopy |
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Abstract |
An amplitude analysis of the decay Lambda(0)(b) -> D(0)p pi(-) is performed in the part of the phase space containing resonances in the D(0)p channel. The study is based on a data sample corresponding to an integrated luminosity of 3.0 fb(-1) of pp collisions recorded by the LHCb experiment. The spectrum of excited Lambda(+)(c) states that decay into D(0)p is studied. The masses, widths and quantum numbers of the Lambda(c)(2880)(+) and Lambda(c) (2940)(+) resonances are measured. The constraints on the spin and parity for the Lambda(c)(2940)(+) state are obtained for the first time. A near-threshold enhancement in the D(0)p amplitude is investigated and found to be consistent with a new resonance, denoted the Lambda(c) (2860)(+), of spin 3/2 and positive parity. |
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Address |
[Bediaga, I.; De Miranda, J. M.; Gomes, A.; Massafferri, A.; Molina Rodriguez, J.; Dos Reis, A. C.; Rodrigues, A. B.; Salustino Guimaraes, V.; Soares Lavra, L.] CBPF, Rio De Janeiro, Brazil, Email: Anton.Poluektov@cern.ch |
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Springer |
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English |
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1029-8479 |
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Expedition |
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Conference |
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Notes |
WOS:000401073500004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3146 |
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Author |
LHCb Collaboration (Aaij, R. et al); Martinez-Vidal, F.; Oyanguren, A.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
Study of eta-eta ' mixing from measurement of B-(s)(0) -> J/psi eta((')) decay rates |
Type |
Journal Article |
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Year |
2015 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
01 |
Issue |
1 |
Pages |
024 - 24pp |
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Keywords |
Spectroscopy; Hadron-Hadron Scattering; QCD; Branching fraction; B physics |
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Abstract |
A study of B and B-s(0) meson decays into J/psi eta and J/psi eta' final states is performed using a data set of proton-proton collisions at centre-of-mass energies of 7 and 8 TeV, collected by the LCHb experiment and corresponding to 3.0 fb(-1) of integrated luminosity. The decay B-0 -> J/psi eta' is observed for the first time. The following ratios of branching fractions are measured: B(B-0 -> J psi eta')/B(B-s(0) -> J psi eta') = (2.28 +/- 0.65 (stat) +/- 0.010 (syst) +/- 0.13 (f(s)/f(d)) x 10(-2) , B(B-0 -> J psi eta')/B(B-s(0) -> J psi eta') = (1.85 +/- 0.65 (stat) +/- 0.09 (syst) +/- 0.11 (f(s)/f(d)) x 10(-2) where the third uncertainty is related to the present knowledge of f(s)/f(d), the ratio between the probabilities for a b quark to form a B-s(0) or a B-0 meson. The branching fraction ratios are used to determine the parameters of eta-eta' meson mixing. In addition, the first evidence for the decay B-s(0) -> psi(2S)' is reported, and the relative branching fraction is measured, B(B-s(0) -> psi(2S)eta')/B(B-s(0) -> J psi eta') = (38.7 +/- 9.0 (stat) +/- 1.3 (syst) +/- 0.9(B)) x 10(-2), where the third uncertainty is due to the limited knowledge of the branching fractions of J/psi and psi(2S) mesons. |
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Address |
[Bediaga, I.; Miranda, J. M. De; Ferreira Rodrigues, F.; Gomes, A.; Marchand, J. F.; Massafferri, A.; Reis, A. C. dos; Rodrigues, A. B.] CBPF, Rio De Janeiro, Brazil, Email: Ivan.Belyaev@itep.ru |
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Springer |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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ISSN |
1029-8479 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000347685500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2077 |
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Author |
LHCb Collaboration (Aaij, R. et al); Garcia Martin, L.M.; Henry, L.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Valls, P.; Sanchez Mayordomo, C. |
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Title |
Resonances and CP violation in B-s(0) and (B)over-bar(s)(0) -> j psi K+K- decays in the mass region above the I center dot(1020) |
Type |
Journal Article |
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Year |
2017 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
037 - 28pp |
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Keywords |
B physics; CP violation; Spectroscopy; Hadron-Hadron scattering (experiments) |
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Abstract |
The decays of B (s) (0) and mesons into the J/psi K (+) K (-) final state are studied in the K (+) K (-) mass region above the I center dot(1020) meson in order to determine the resonant substructure and measure the CP-violating phase, I center dot (s) , the decay width, I“ (s) , and the width difference between light and heavy mass eigenstates, Delta I” (s) . A decay-time dependent amplitude analysis is employed. The data sample corresponds to an integrated luminosity of 3 fb(-1) produced in 7 and 8 TeV pp collisions at the LHC, collected by the LHCb experiment. The measurement determines I center dot (s) = 119 +/- 107 +/- 34 mrad. A combination with previous LHCb measurements using similar decays into the J/psi pi (+) pi (-) and J/psi I center dot(1020) final states gives I center dot (s) = 1 +/- 37 mrad, consistent with the Standard Model prediction. |
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Address |
[Bediaga, I.; Miranda, J. M. De; Massafferri, A.; Molina Rodriguez, J.; Reis, A. C. dos; Rodrigues, A. B.; Salustino Guimaraes, V.; Soares Lavra, I.; Tourinho Jadallah Aoude, R.] Ctr Brasileiro Pesquisas Fis, Rio De Janeiro, Brazil, Email: liming.zhang@cern.ch |
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Springer |
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English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000407690800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3255 |
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| Permanent link to this record |
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Author |
LHCb Collaboration (Aaij, R. et al); Garcia Martin, L.M.; Henry, L.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Vidal, J.; Sanchez Mayordomo, C. |
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Title |
Observation of the decay Lambda(0)(b) -> psi(2S)p pi(-) |
Type |
Journal Article |
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Year |
2018 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
131 - 18pp |
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Keywords |
B physics; Flavor physics; Hadron-Hadron scattering (experiments); Spectroscopy |
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Abstract |
The Cabibbo-suppressed decay Lambda(0)(b) -> psi(2S)p pi(-) is observed for the fi rst time using a data sample collected by the LHCb experiment in proton-proton collisions corresponding to 1.0, 2.0 and 1.9 fb(-1) of integrated luminosity at centre-of-mass energies of 7, 8 and 13TeV, respectively. The psi(2S) mesons are reconstructed in the mu(+)mu(-) fi nal state. The branching fraction with respect to that of the Lambda(0)(b) -> psi(2S)pK(-) decay mode is measured to be B (Lambda(0)(b) -> psi(2S)p pi(-))/B (Lambda(0)(b) -> psi(2S)pK(-)) = (11.44 +/- 1.3 +/- 0.2)%, where the fi rst uncertainty is statistical and the second is systematic. The psi(2S) p and psi(2S)pi(-) mass spectra are investigated and no evidence for exotic resonances is found. |
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Address |
[Bediaga, I.; Torres, M. Cruz; De Miranda, J. M.; Gomes, A.; Massafferri, A.; Rodriguez, J. Molina; dos Reis, A. C.; Lavra, L. Soares; Aoude, R. Tourinho Jadallah] Ctr Brasileiro Pesquisas Fis, Rio De Janeiro, Brazil, Email: Ivan.Belyaev@itep.ru |
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Corporate Author |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000442698800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3707 |
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Author |
LHCb Collaboration (Aaij, R. et al); Garcia Martin, L.M.; Henry, L.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Valls, P.; Ruiz Vidal, J.; Sanchez Mayordomo, C. |
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Title |
Measurements of the branching fractions of Lambda(+)(c) -> p pi(-)pi(+), Lambda(+)(c) -> pK(-)K(+), and Lambda(+)(c) -> p pi K-(+) |
Type |
Journal Article |
| |
Year |
2018 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
03 |
Issue |
3 |
Pages |
043 - 23pp |
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Keywords |
Branching fraction; Charm physics; Flavor physics; Hadron-Hadron scattering (experiments); Spectroscopy |
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Abstract |
The ratios of the branching fractions of the decays do Lambda(+)(c) -> , p pi(-)pi(+), Lambda(+->)(c) pK(-)K(+), and Lambda(+)(c) -> p pi K--(+) with respect to the Cabibbo-favoured Lambda(+)(c) -> pK(-)pi(+) decay are measured using proton-proton collision data collected with the LHCb experiment at a 7 TeV centre-of-mass energy and corresponding to an integrated luminosity of 1.0 fb(-1): B(Lambda(+)(c) -> p pi(-)pi(+))/B(Lambda(+)(c) -> pK(-)pi(+)) = (7.44 +/- 0.08 +/- 0.18)%. B(Lambda(+)(c) -> pK(-)K(+))/B(Lambda(+)(c) -> pK(-)pi(+) = (1.70 +/- 0.03 +/- 0.03)%, B(Lambda(+)(c) -> p pi(-)pi K-+(+))/B(Lambda(+)(c) -> pK(-)pi(+) = (0.165 +/- 0.015 +/- 0.005)%, where the uncertainties are statistical and systematic, respectively. These results are the most precise measurements of these quantities to date. When multiplied by the world average value for B(Lambda(+)(c) -> p pi(-)pi(+)), the corresponding branching fractions are B(Lambda(+)(c) -> p pi(-)pi(+) = (4.72 +/- 0.05 +/- 0.11 +/- 0.25) x 10(-3), B(Lambda(+)(c) -> pK(-)K(+)) = (1.08 +/- 0.02 +/- 0.02 +/- 0.06) x 10(-3), B(Lambda(+)(c) -> , p pi K--(+)) = (1.04 +/- 0.09 +/- 0.03 +/- 0.05) x 10(-4), where the final uncertainty is due to B(Lambda(+)(c) -> pK(-)pi(+)). |
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Address |
[Bediaga, I.; Torresl, M. Cruz; De Miranda, J. M.; Gomes, A.; Massafferri, A.; Rodriguez, J. Molina; dos Reis, A. C.; Rodrigues, A. B.; Guimaraes, V. Salustino; Lavra, I. Soares; Aoudel, R. Tourinho Jadallah] CBPF, Rio De Janeiro, Brazil, Email: stephen.ogilvy@cern.ch |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000427543500002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3532 |
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Author |
AGATA Collaboration (Akkoyun, S. et al); Algora, A.; Barrientos, D.; Domingo-Pardo, C.; Egea, F.J.; Gadea, A.; Huyuk, T.; Kaci, M.; Mendez, V.; Rubio, B.; Salt, J.; Tain, J.L. |
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Title |
AGATA-Advanced GAmma Tracking Array |
Type |
Journal Article |
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Year |
2012 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
668 |
Issue |
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Pages |
26-58 |
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Keywords |
AGATA; gamma-Ray spectroscopy; gamma-Ray tracking; HPGe detectors; Digital signal processing; Pulse-shape and gamma-ray tracking algorithms; Semiconductor detector performance and simulations |
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Abstract |
The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation gamma-ray spectrometer. AGATA is based on the technique of gamma-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a gamma ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realisation of gamma-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterisation of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorithms, to extract energy, time and position, to be employed. In addition, tracking algorithms for event reconstruction were developed. The first phase of AGATA is now complete and operational in its first physics campaign. In the future AGATA will be moved between laboratories in Europe and operated in a series of campaigns to take advantage of the different beams and facilities available to maximise its science output. The paper reviews all the achievements made in the AGATA project including all the necessary infrastructure to operate and support the spectrometer. |
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Address |
[Boston, A. J.; Boston, H. C.; Colosimo, S.; Cooper, R. J.; Cresswell, J. R.; Dimmock, M. R.; Filmer, F.; Grint, A. N.; Harkness, L. J.; Judson, D. S.; Mather, A. R.; Moon, S.; Nelson, L.; Nolan, P. J.; Norman, M.; Oxley, D. C.; Rigby, S.; Sampson, J.; Scraggs, D. P.; Seddon, D.; Slee, M.; Stanios, T.; Thornhill, J.; Unsworth, C.; Wells, D.] Univ Liverpool, Oliver Lodge Lab, Liverpool L69 7ZE, Merseyside, England, Email: a.j.boston@liverpool.ac.uk |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000300864200005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
923 |
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Author |
AGATA Collaboration (Crespi, F.C.L. et al); Gadea, A. |
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Title |
Response of AGATA segmented HPGe detectors to gamma rays up to 15.1 MeV |
Type |
Journal Article |
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Year |
2013 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
705 |
Issue |
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Pages |
47-54 |
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Keywords |
AGATA; Gamma-ray spectroscopy; Gamma-ray tracking; HPGe detectors; Pulse-shape and gamma-ray tracking algorithms; Semiconductor detector performance and simulations |
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Abstract |
The response of AGATA segmented HPGe detectors to gamma rays in the energy range 2-15 MeV was measured. The 15.1 MeV gamma rays were produced using the reaction d(B-11,n gamma)C-12 at E-beam=19.1 MeV, while gamma rays between 2 and 9 MeV were produced using an Am-Be-Fe radioactive source. The energy resolution and linearity were studied and the energy-to-pulse-height conversion resulted to be linear within 0.05%.Experimental interaction multiplicity distributions are discussed and compared with the results of Geant4 simulations. It is shown that the application of gamma-ray tracking allows a suppression of background radiation caused by n-capture in Ge nuclei. Finally the Doppler correction for the 15.1 MeV gamma line, performed using the position information extracted with Pulse-shape analysis is discussed. |
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[Crespi, F. C. L.; Avigo, R.; Camera, F.; Bottoni, S.; Bracco, A.; Ceruti, S.; Giaz, A.; Leoni, S.; Nicolini, R.; Pellegri, L.; Riboldi, S.; Vandone, V.] Univ Milan, Dipartimento Fis, I-20133 Milan, Italy, Email: fabio.crespi@mi.infn.it |
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Elsevier Science Bv |
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English |
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0168-9002 |
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WOS:000314826000009 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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IFIC @ pastor @ |
Serial |
1329 |
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Author |
Di Gregorio, E.; Staelens, M.; Hosseinkhah, N.; Karimpoor, M.; Liburd, J.; Lim, L.; Shankar, K.; Tuszynski, J.A. |
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Title |
Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases |
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Journal Article |
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Year |
2024 |
Publication |
Nanomaterials |
Abbreviated Journal |
Nanomaterials |
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Volume |
14 |
Issue |
13 |
Pages |
1093 - 21pp |
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Keywords |
proteins; protein dynamics; protein structure; non-invasive therapies; low-level laser therapy; spectroscopy; amide bands; amide I; spectral decomposition |
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In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition. |
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Address |
[Di Gregorio, Elisabetta; Staelens, Michael; Tuszynski, Jack A.] Univ Alberta, Fac Sci, Dept Phys, Edmonton, AB T6G 2E1, Canada, Email: michael.staelens@ific.uv.es |
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Mdpi |
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English |
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WOS:001269841000001 |
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no |
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Is ISI |
yes |
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yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6204 |
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