Ibanez-Rosello, B., Bautista-Ballesteros, J. A., Candela-Juan, C., Villaescusa, J. I., Ballester, F., Vijande, J., et al. (2017). Evaluation of the shielding in a treatment room with an electronic brachytherapy unit. J. Radiol. Prot., 37(2), N5–N12.
Abstract: Esteya (R) (Elekta Brachytherapy, Veenendaal, The Netherlands) is an electronic brachytherapy (eBT) system based on a 69.5 kVp x-ray source and a set of collimators of 1 to 3 cm in diameter, used for treating non-melanoma skin cancer lesions. This study aims to estimate room shielding requirements for this unit. The non-primary (scattered and leakage) ambient dose equivalent rates were measured with a Berthold LB-133 monitor (Berthold Technologies, Bad Wildbad, Germany). The latter ranges from 17 mSv h(-1) at 0.25 m distance from the x-ray source to 0.1 mSv h(-1) at 2.5 m. The necessary room shielding was then estimated following US and some European guidelines. The room shielding for all barriers considered was below 2 mmPb. The dose to a companion who, exceptionally, would stay with the patient during all treatment was estimated to be below 1 mSv if a leaded apron is used. In conclusion, Esteya shielding requirements are minimal.
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Husek, T., Monsalvez-Pozo, K., & Portoles, J. (2021). Lepton-flavour violation in hadronic tau decays and mu-tau conversion in nuclei. J. High Energy Phys., 01(1), 059–48pp.
Abstract: Within the Standard Model Effective Field Theory framework, with operators up to dimension 6, we perform a model-independent analysis of the lepton-flavour-violating processes involving tau leptons. Namely, we study hadronic tau decays and l-tau conversion in nuclei, with l = e, mu. Based on available experimental limits, we establish constraints on the Wilson coefficients of the operators contributing to these processes. Our work paves the way to extract the related information from Belle II and foreseen future experiments.
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Husek, T., Monsalvez-Pozo, K., & Portoles, J. (2022). Constraints on leptoquarks from lepton-flavour-violating tau-lepton processes. J. High Energy Phys., 04(4), 165–31pp.
Abstract: Leptoquarks are ubiquitous in several extensions of the Standard Model and seem to be able to accommodate the universality-violation-driven B-meson-decay anomalies and the (g-2)(mu) discrepancy interpreted as deviations from the Standard Model predictions. In addition, the search for lepton-flavour violation in the charged sector is, at present, a major research program that could also be facilitated by the dynamics generated by leptoquarks. In this article, we consider a rather wide framework of both scalar and vector leptoquarks as the generators of lepton-flavour violation in processes involving the tau lepton. We single out its couplings to leptoquarks, thus breaking universality in the lepton sector, and we integrate out leptoquarks at tree level, generating the corresponding dimension-6 operators of the Standard Model Effective Field Theory. In ref. [1] we obtained model-independent bounds on the Wilson coefficients of those operators contributing to lepton-flavour-violating hadron tau decays and l-tau conversion in nuclei, with l = e, mu. Hence, we use those results to translate the bounds into the couplings of leptoquarks to the Standard Model fermions.
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Hueso-Gonzalez, F., Ballester, F., Perez-Calatayud, J., Siebert, F. A., & Vijande, J. (2017). Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent I-125 prostate brachytherapy. Brachytherapy, 16(3), 616–623.
Abstract: PURPOSE: RayStretch is a simple algorithm proposed for heterogeneity corrections in low-dose-rate brachytherapy. It is built on top of TG-43 consensus data, and it has been validated with Monte Carlo (MC) simulations. In this study, we take a real clinical prostate implant with 71 1251 seeds as reference and we apply RayStretch to analyze its performance in worst-case scenarios. METHODS AND MATERIALS: To do so, we design two cases where large calcifications are located in the prostate lobules. RayStretch resilience under various calcification density values is also explored. Comparisons against MC calculations are performed. RESULTS: Dose volume histogram related parameters like prostate D-90, rectum D-2cc, or urethra D-10 obtained with RayStretch agree within a few percent with the detailed MC results for all cases considered. CONCLUSIONS: The robustness and compatibility of RayStretch with commercial treatment planning systems indicate its applicability in clinical practice for dosimetric corrections in prostate calcifications. Its use during intraoperative ultrasound planning is foreseen.
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Hueso-Gonzalez, F., Vijande, J., Ballester, F., Perez-Calatayud, J., & Siebert, F. A. (2015). A simple analytical method for heterogeneity corrections in low dose rate prostate brachytherapy. Phys. Med. Biol., 60(14), 5455–5469.
Abstract: In low energy brachytherapy, the presence of tissue heterogeneities contributes significantly to the discrepancies observed between treatment plan and delivered dose. In this work, we present a simplified analytical dose calculation algorithm for heterogeneous tissue. We compare it with Monte Carlo computations and assess its suitability for integration in clinical treatment planning systems. The algorithm, named as RayStretch, is based on the classic equivalent path length method and TG-43 reference data. Analytical and Monte Carlo dose calculations using Penelope2008 are compared for a benchmark case: a prostate patient with calcifications. The results show a remarkable agreement between simulation and algorithm, the latter having, in addition, a high calculation speed. The proposed analytical model is compatible with clinical real-time treatment planning systems based on TG-43 consensus datasets for improving dose calculation and treatment quality in heterogeneous tissue. Moreover, the algorithm is applicable for any type of heterogeneities.
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Huang, J. W., Madden, A., Racco, D., & Reig, M. (2020). Maximal axion misalignment from a minimal model. J. High Energy Phys., 10(10), 143–39pp.
Abstract: The QCD axion is one of the best motivated dark matter candidates. The misalignment mechanism is well known to produce an abundance of the QCD axion consistent with dark matter for an axion decay constant of order 10(12) GeV. For a smaller decay constant, the QCD axion, with Peccei-Quinn symmetry broken during inflation, makes up only a fraction of dark matter unless the axion field starts oscillating very close to the top of its potential, in a scenario called “large-misalignment”. In this scenario, QCD axion dark matter with a small axion decay constant is partially comprised of very dense structures. We present a simple dynamical model realising the large-misalignment mechanism. During inflation, the axion classically rolls down its potential approaching its minimum. After inflation, the Universe reheats to a high temperature and a modulus (real scalar field) changes the sign of its minimum dynamically, which changes the sign of the mass of a vector-like fermion charged under QCD. As a result, the minimum of the axion potential during inflation becomes the maximum of the potential after the Universe has cooled through the QCD phase transition and the axion starts oscillating. In this model, we can produce QCD axion dark matter with a decay constant as low as 6 x 10(9) GeV and an axion mass up to 1 meV. We also summarise the phenomenological implications of this mechanism for dark matter experiments and colliders.
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Hooper, D., Leane, R. K., Tsai, Y. D., Wegsman, S., & Witte, S. J. (2020). A systematic study of hidden sector dark matter: application to the gamma-ray and antiproton excesses. J. High Energy Phys., 07(7), 163–38pp.
Abstract: In hidden sector models, dark matter does not directly couple to the particle content of the Standard Model, strongly suppressing rates at direct detection experiments, while still allowing for large signals from annihilation. In this paper, we conduct an extensive study of hidden sector dark matter, covering a wide range of dark matter spins, mediator spins, interaction diagrams, and annihilation final states, in each case determining whether the annihilations are s-wave (thus enabling efficient annihilation in the universe today). We then go on to consider a variety of portal interactions that allow the hidden sector annihilation products to decay into the Standard Model. We broadly classify constraints from relic density requirements and dwarf spheroidal galaxy observations. In the scenario that the hidden sector was in equilibrium with the Standard Model in the early universe, we place a lower bound on the portal coupling, as well as on the dark matter's elastic scattering cross section with nuclei. We apply our hidden sector results to the observed Galactic Center gamma-ray excess and the cosmic-ray antiproton excess. We find that both of these excesses can be simultaneously explained by a variety of hidden sector models, without any tension with constraints from observations of dwarf spheroidal galaxies.
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Hirsch, M., Lineros, R. A., Morisi, S., Palacio, J., Rojas, N., & Valle, J. W. F. (2013). WIMP dark matter as radiative neutrino mass messenger. J. High Energy Phys., 10(10), 149–18pp.
Abstract: The minimal seesaw extension of the Standard SU(3)(c)circle times SU(2)(L)circle times U(1)(Y) Model requires two electroweak singlet fermions in order to accommodate the neutrino oscillation parameters at tree level. Here we consider a next to minimal extension where light neutrino masses are generated radiatively by two electroweak fermions: one singlet and one triplet under SU(2)(L). These should be odd under a parity symmetry and their mixing gives rise to a stable weakly interactive massive particle (WIMP) dark matter candidate. For mass in the GeV-TeV range, it reproduces the correct relic density, and provides an observable signal in nuclear recoil direct detection experiments. The fermion triplet component of the dark matter has gauge interactions, making it also detectable at present and near future collider experiments.
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Herrero-Garcia, J., Schwetz, T., & Zupan, J. (2012). On the annual modulation signal in dark matter direct detection. J. Cosmol. Astropart. Phys., 03(3), 005–28pp.
Abstract: We derive constraints on the annual modulation signal in Dark Matter (DM) direct detection experiments in terms of the unmodulated event rate. A general bound independent of the details of the DM distribution follows from the assumption that the motion of the earth around the sun is the only source of time variation. The bound is valid for a very general class of particle physics models and also holds in the presence of an unknown unmodulated background. More stringent bounds are obtained, if modest assumptions on symmetry properties of the DM halo are adopted. We illustrate the bounds by applying them to the annual modulation signals reported by the DAMA and CoGeNT experiments in the framework of spin-independent elastic scattering. While the DAMA signal satisfies our bounds, severe restrictions on the DM mass can be set for CoGeNT.
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Hernandez, P., Kekic, M., Lopez-Pavon, J., Racker, J., & Salvado, J. (2016). Testable baryogenesis is in seesaw models. J. High Energy Phys., 08(8), 157–29pp.
Abstract: We revisit the production of baryon asymmetries in the minimal type I seesaw model with heavy Majorana singlets in the GeV range. In particular we include “washout” effects from scattering processes with gauge bosons, Higgs decays and inverse decays, besides the dominant top scatterings. We show that in the minimal model with two singlets, and for an inverted light neutrino ordering, future measurements from SHiP and neutrinoless double beta decay could in principle provide sufficient information to predict the matter-antimatter asymmetry in the universe. We also show that SHiP measurements could provide very valuable information on the PMNS CP phases.
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