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Author |
Robert, C.; Dedes, G.; Battistoni, G.; Bohlen, T.T.; Buvat, I.; Cerutti, F.; Chin, M.P.W.; Ferrari, A.; Gueth, P.; Kurz, C.; Lestand, L.; Mairani, A.; Montarou, G.; Nicolini, R.; Ortega, P.G.; Parodi, K.; Prezado, Y.; Sala, P.R.; Sarrut, D.; Testa, E. |
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Title |
Distributions of secondary particles in proton and carbon-ion therapy: a comparison between GATE/Geant4 and FLUKA Monte Carlo codes |
Type |
Journal Article |
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Year |
2013 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
58 |
Issue |
9 |
Pages |
2879-2899 |
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Keywords |
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Abstract |
Monte Carlo simulations play a crucial role for in-vivo treatment monitoring based on PET and prompt gamma imaging in proton and carbon-ion therapies. The accuracy of the nuclear fragmentation models implemented in these codes might affect the quality of the treatment verification. In this paper, we investigate the nuclear models implemented in GATE/Geant4 and FLUKA by comparing the angular and energy distributions of secondary particles exiting a homogeneous target of PMMA. Comparison results were restricted to fragmentation of O-16 and C-12. Despite the very simple target and set-up, substantial discrepancies were observed between the two codes. For instance, the number of high energy (>1 MeV) prompt gammas exiting the target was about twice as large with GATE/Geant4 than with FLUKA both for proton and carbon ion beams. Such differences were not observed for the predicted annihilation photon production yields, for which ratios of 1.09 and 1.20 were obtained between GATE and FLUKA for the proton beam and the carbon ion beam, respectively. For neutrons and protons, discrepancies from 14% (exiting protons-carbon ion beam) to 57% (exiting neutrons-proton beam) have been identified in production yields as well as in the energy spectra for neutrons. |
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Address  |
Univ Paris 07, IMNC, CNRS, UMR 8165, F-91406 Orsay, France, Email: robert@imnc.in2p3.fr |
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Iop Publishing Ltd |
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English |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000317579900010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1407 |
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Author |
Albaladejo, M.; Fernandez-Soler, P.; Nieves, J.; Ortega, P.G. |
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Title |
Lowest-lying even-parity (B)over-bar(s) mesons: heavy-quark spin-flavor symmetry, chiral dynamics, and constituent quark-model bare masses |
Type |
Journal Article |
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Year |
2017 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
77 |
Issue |
3 |
Pages |
170 - 9pp |
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Keywords |
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Abstract |
The discovery of the D*(s0)(2317) and D-s1(2460) resonances in the charmed-strange meson spectra revealed that formerly successful constituent quark models lose predictability in the vicinity of two-meson thresholds. The emergence of non-negligible effects due to meson loops requires an explicit evaluation of the interplay between Q (q) over bar and (Q (q) over bar)(q (q) over bar) Fock components. In contrast to the c (s) over bar sector, there is no experimental evidence of J(P) = 0(+), 1(+) bottom-strange states yet. Motivated by recent lattice studies, in this work the heavy-quark partners of the D*(s0)(2317) and D-s1(2460) states are analyzed within a heavy meson chiral unitary scheme. As a novelty, the coupling between the constituent quark-model P-wave (B) over bar (s) scalar and axial mesons and the (B) over bar (()*()) K channels is incorporated employing an effective interaction, consistent with heavy-quark spin symmetry, constrained by the lattice energy levels. |
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Address |
[Albaladejo, M.; Fernandez-Soler, P.; Nieves, J.; Ortega, P. G.] Univ Valencia, Inst Invest Paterna, Ctr Mixto CSIC, Inst Fis Corpuscular IFIC, Aptd 22085, Valencia 46071, Spain, Email: ortegapg@gmail.com |
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Publisher |
Springer |
Place of Publication |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6044 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000400018400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3076 |
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Author |
Albaladejo, M.; Fernandez-Soler, P.; Nieves, J.; Ortega, P.G. |
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Title |
Contribution of constituent quark model c(s)over-bar states to the dynamics of the D*s0 (2317) and Ds1(2460) resonances |
Type |
Journal Article |
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Year |
2018 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
78 |
Issue |
9 |
Pages |
722 - 22pp |
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Keywords |
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Abstract |
The masses of the D*(s0) (2317) and D-s1(2460) resonances lie below the DK and D* K thresholds respectively, which contradicts the predictions of naive quark models and points out to non-negligible effects of the D(*) K loops in the dynamics of the even-parity scalar (J(pi) = 0(+)) and axial-vector (J(pi) = 1(+)) c (s) over bar systems. Recent lattice QCD studies, incorporating the effects of the D(*) K channels, analyzed these spin-parity sectors and correctly described the D*(s0)(2317) – D-s1(2460) mass splitting. Motivated by such works, we study the structure of the D*(s0)(2317) and D-s1(2460) resonances in the framework of an effective field theory consistent with heavy quark spin symmetry, and that incorporates the interplay between D(*) K meson-meson degrees of freedom and bare P-wave c (s) over bar states predicted by constituent quark models. We extend the scheme to finite volumes and fit the strength of the coupling between both types of degrees of freedom to the available lattice levels, which we successfully describe. We finally estimate the size of the D(*) K two-meson components in the D*(s0)(2317) and D-s1(2460) resonances, and we conclude that these states have a predominantly hadronic-molecular structure, and that it should not be tried to accommodate these mesons within c (s) over bar constituent quark model patterns. |
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Address |
[Albaladejo, Miguel] Univ Murcia, Dept Fis, E-30071 Murcia, Spain, Email: albaladejo@um.es; |
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Corporate Author |
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Publisher |
Springer |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6044 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000443822000003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
3714 |
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Author |
Muñoz, E.; Barrio, J.; Etxebeste, A.; Ortega, P.G.; Lacasta, C.; Oliver, J.F.; Solaz, C.; Llosa, G. |
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Title |
Performance evaluation of MACACO: a multilayer Compton camera |
Type |
Journal Article |
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Year |
2017 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
62 |
Issue |
18 |
Pages |
7321-7341 |
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Keywords |
Compton imaging; Compton camera; continuous LaBr3 crystal; silicon photomultiplier; hadron therapy |
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Abstract |
Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm. |
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Address |
[Munoz, Enrique; Barrio, John; Etxebeste, Ane; Ortega, Pablo G.; Lacasta, Carlos; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es |
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Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000408229900003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3253 |
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Author |
Ortega, P.G.; Torres-Espallardo, I.; Cerutti, F.; Ferrari, A.; Gillam, J.E.; Lacasta, C.; Llosa, G.; Oliver, J.F.; Sala, P.R.; Solevi, P.; Rafecas, M. |
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Title |
Noise evaluation of Compton camera imaging for proton therapy |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
5 |
Pages |
1845-1863 |
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Keywords |
proton therapy; Compton camera; Monte Carlo methods; FLUKA; prompt gamma; range verification; MLEM |
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Abstract |
Compton Cameras emerged as an alternative for real-time dose monitoring techniques for Particle Therapy (PT), based on the detection of prompt-gammas. As a consequence of the Compton scattering process, the gamma origin point can be restricted onto the surface of a cone (Compton cone). Through image reconstruction techniques, the distribution of the gamma emitters can be estimated, using cone-surfaces backprojections of the Compton cones through the image space, along with more sophisticated statistical methods to improve the image quality. To calculate the Compton cone required for image reconstruction, either two interactions, the last being photoelectric absorption, or three scatter interactions are needed. Because of the high energy of the photons in PT the first option might not be adequate, as the photon is not absorbed in general. However, the second option is less efficient. That is the reason to resort to spectral reconstructions, where the incoming. energy is considered as a variable in the reconstruction inverse problem. Jointly with prompt gamma, secondary neutrons and scattered photons, not strongly correlated with the dose map, can also reach the imaging detector and produce false events. These events deteriorate the image quality. Also, high intensity beams can produce particle accumulation in the camera, which lead to an increase of random coincidences, meaning events which gather measurements from different incoming particles. The noise scenario is expected to be different if double or triple events are used, and consequently, the reconstructed images can be affected differently by spurious data. The aim of the present work is to study the effect of false events in the reconstructed image, evaluating their impact in the determination of the beam particle ranges. A simulation study that includes misidentified events (neutrons and random coincidences) in the final image of a Compton Telescope for PT monitoring is presented. The complete chain of detection, from the beam particle entering a phantom to the event classification, is simulated using FLUKA. The range determination is later estimated from the reconstructed image obtained from a two and three-event algorithm based on Maximum Likelihood Expectation Maximization. The neutron background and random coincidences due to a therapeutic-like time structure are analyzed for mono-energetic proton beams. The time structure of the beam is included in the simulations, which will affect the rate of particles entering the detector. |
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Address |
[Ortega, P. G.; Cerutti, F.; Ferrari, A.] CERN European Org Nucl Res, CH-1217 Meyrin, Switzerland, Email: pgarciao@cern.ch |
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Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000349530700009 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2115 |
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| Permanent link to this record |
