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Author Pedersen, L.G. et al; Morales, A.I. doi  openurl
  Title First spectroscopic study of odd-odd 78Cu Type Journal Article
  Year 2023 Publication Physical Review C Abbreviated Journal Phys. Rev. C  
  Volume 107 Issue 4 Pages 044301 - 10pp  
  Keywords  
  Abstract (up) Nuclei in the vicinity of 78Ni are important benchmarks for nuclear structure, which can reveal changes in the shell structure far from stability. Spectroscopy of the odd-odd isotope 78Cu was performed for the first time in an experiment with the EURICA setup at the Radioactive Isotope Beam Factory at RIKEN Nishina Center. Excited states in the neutron-rich isotope were populated following the beta decay of 78Ni produced by in-flight fission and and separated by the BigRIPS separator. A level scheme based on the analysis of γ−γ coincidences is presented. Tentative spin and parity assignments were made when possible based on the β-decay feeding intensities and γ-decay properties of the excited states. Time correlations between β and γ decay show clear indications of an isomeric state with a half-life of 3.8(4) ms. Large-scale Monte Carlo shell-model calculations were performed using the A3DA-m interaction and a valence space comprising the full fp shell and the 1g9/2 and 2d5/2 orbitals for both protons and neutrons. The comparison of the experimental results with the shell-model calculations allows interpreting the excited states in terms of spin multiplets arising from the proton-neutron interaction. The results provide further insight into the evolution of the proton single-particle orbitals as a function of neutron number, and quantitative information about the proton-neutron interaction outside the doubly magic 78Ni core.  
  Address [Pedersen, L. G.; Sahin, E.; Gorgen, A.; Garrote, F. L. Bello; Modamio, V.] Univ Oslo, Dept Phys, NO-0316 Oslo, Norway, Email: l.g.pedersen@fys.uio.no;  
  Corporate Author Thesis  
  Publisher Amer Physical Soc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2469-9985 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000998180300003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5572  
Permanent link to this record
 

 
Author Borja-Lloret, M.; Barrientos, L.; Bernabeu, J.; Lacasta, C.; Muñoz, E.; Ros, A.; Roser, J.; Viegas, R.; Llosa, G. doi  openurl
  Title Influence of the background in Compton camera images for proton therapy treatment monitoring Type Journal Article
  Year 2023 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 68 Issue 14 Pages 144001 - 16pp  
  Keywords Compton imaging; Compton camera; proton therapy; treatment monitoring; Monte Carlo simulation; image reconstruction; background  
  Abstract (up) Objective. Background events are one of the most relevant contributions to image degradation in Compton camera imaging for hadron therapy treatment monitoring. A study of the background and its contribution to image degradation is important to define future strategies to reduce the background in the system. Approach. In this simulation study, the percentage of different kinds of events and their contribution to the reconstructed image in a two-layer Compton camera have been evaluated. To this end, GATE v8.2 simulations of a proton beam impinging on a PMMA phantom have been carried out, for different proton beam energies and at different beam intensities. Main results. For a simulated Compton camera made of Lanthanum (III) Bromide monolithic crystals, coincidences caused by neutrons arriving from the phantom are the most common type of background produced by secondary radiations in the Compton camera, causing between 13% and 33% of the detected coincidences, depending on the beam energy. Results also show that random coincidences are a significant cause of image degradation at high beam intensities, and their influence in the reconstructed images is studied for values of the time coincidence windows from 500 ps to 100 ns. Significance. Results indicate the timing capabilities required to retrieve the fall-off position with good precision. Still, the noise observed in the image when no randoms are considered make us consider further background rejection methods.  
  Address [Borja-Lloret, M.; Barrientos, L.; Bernabeu, J.; Lacasta, C.; Munoz, E.; Ros, A.; Roser, J.; Viegas, R.; Llosa, G.] Inst Fis Corpuscular IFIC, CSIC UV, Valencia, Spain, Email: Marina.Borja@csic.es  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001022671300001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5571  
Permanent link to this record
 

 
Author Brzezinski, K. et al doi  openurl
  Title Detection of range shifts in proton beam therapy using the J-PET scanner: a patient simulation study Type Journal Article
  Year 2023 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 68 Issue 14 Pages 145016 - 17pp  
  Keywords proton therapy; positron emission tomography; in vivo range verification; J-PET; Monte Carlo  
  Abstract (up) Objective. The Jagiellonian positron emission tomography (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET for range monitoring by means of a detailed Monte Carlo simulation study of 95 patients who underwent proton therapy at the Cyclotron Centre Bronowice (CCB) in Krakow, Poland. Approach. Discrepancies between prescribed and delivered treatments were artificially introduced in the simulations by means of shifts in patient positioning and in the Hounsfield unit to the relative proton stopping power calibration curve. A dual-layer, cylindrical J-PET geometry was simulated in an in-room monitoring scenario and a triple-layer, dual-head geometry in an in-beam protocol. The distribution of range shifts in reconstructed PET activity was visualized in the beam's eye view. Linear prediction models were constructed from all patients in the cohort, using the mean shift in reconstructed PET activity as a predictor of the mean proton range deviation. Main results. Maps of deviations in the range of reconstructed PET distributions showed agreement with those of deviations in dose range in most patients. The linear prediction model showed a good fit, with coefficient of determination r (2) = 0.84 (in-room) and 0.75 (in-beam). Residual standard error was below 1 mm: 0.33 mm (in-room) and 0.23 mm (in-beam). Significance. The precision of the proposed prediction models shows the sensitivity of the proposed J-PET scanners to shifts in proton range for a wide range of clinical treatment plans. Furthermore, it motivates the use of such models as a tool for predicting proton range deviations and opens up new prospects for investigations into the use of intra-treatment PET images for predicting clinical metrics that aid in the assessment of the quality of delivered treatment.  
  Address [Brzezinski, Karol; Gajewski, Jan; Kopec, Renata; Olko, Pawel; Stasica, Paulina; Rucinski, Antoni] Polish Acad Sci, Inst Nucl Phys, Krakow, Poland, Email: karol.brzezinski@ific.uv.es  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001026535700001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5616  
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Author Borys, D. et al; Brzezinski, K. doi  openurl
  Title ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging Type Journal Article
  Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 67 Issue 22 Pages 224002 - 15pp  
  Keywords proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging  
  Abstract (up) Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).  
  Address [Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000885248200001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5416  
Permanent link to this record
 

 
Author Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G. doi  openurl
  Title Joint image reconstruction algorithm in Compton cameras Type Journal Article
  Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 67 Issue 15 Pages 155009 - 15pp  
  Keywords Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope  
  Abstract (up) Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging.  
  Address [Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000827830200001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5298  
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Author Bernabeu, J.; Segarra, A. url  doi
openurl 
  Title Do T asymmetries for neutrino oscillations in uniform matter have a CP-even component? Type Journal Article
  Year 2019 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.  
  Volume 03 Issue 3 Pages 103 - 12pp  
  Keywords CP violation; Discrete Symmetries; Neutrino Physics  
  Abstract (up) Observables of neutrino oscillations in matter have, in general, contributions from the effective matter potential. It contaminates the CP violation asymmetry adding a fake effect that has been recently disentangled from the genuine one by their different behavior under T and CPT. Is the genuine T-odd CPT-invariant component of the CP asymmetry coincident with the T asymmetry? Contrary to CP, matter effects in uniform matter cannot induce by themselves a non-vanishing T asymmetry; however, the question of the title remained open. We demonstrate that, in the presence of genuine CP violation, there is a new non-vanishing CP-even, and so CPT-odd, component in the T asymmetry in matter, which is of odd-parity in both the phase delta of the flavor mixing and the matter parameter a. The two disentangled components, genuine A(alpha beta)(T;CP) and fake A(alpha beta)(T;CPT), could be experimentally separated by the measurement of the two T asymmetries in matter (nu(alpha) <-> nu(beta)) and ((nu) over bar <-> (nu) over bar (beta)). For the (nu(mu) <-> nu(e)) transitions, the energy dependence of the new A(mu e)(T;CPT) component is like the matter-induced term A(mu e)(CP;CPT) of the CP asymmetry which is odd under a change of the neutrino mass hierarchy. We have thus completed the physics involved in all observable asymmetries in matter by means of their disentanglement into the three independent components, genuine A(alpha beta)(CP;T) and fake A(alpha beta)(CP;CPT) and A(alpha beta)(T;CPT).  
  Address [Bernabeu, Jose] Univ Valencia, Dept Fis Teor, CSIC, E-46100 Valencia, Spain, Email: Jose.Bernabeu@uv.es;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1029-8479 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000462327100001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 3961  
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Author LHCb Collaboration (Aaij, R. et al); Garcia Martin, L.M.; Henry, L.; Jashal, B.K.; Martinez-Vidal, F.; Oyanguren, A.; Remon Alepuz, C.; Ruiz Vidal, J.; Sanchez Mayordomo, C. url  doi
openurl 
  Title Observation of Several Sources of CP Violation in B+ -> pi(+)pi(+)pi(-) Decays Type Journal Article
  Year 2020 Publication Physical Review Letters Abbreviated Journal Phys. Rev. Lett.  
  Volume 124 Issue 3 Pages 031801 - 11pp  
  Keywords  
  Abstract (up) Observations are reported of different sources of CP violation from an amplitude analysis of B+ -> pi(+)pi(+)pi(-) decays, based on a data sample corresponding to an integrated luminosity of 3 fb(-1) of pp collisions recorded with the LHCb detector. A large CP asymmetry is observed in the decay amplitude involving the tensor f(2)(1270) resonance, and in addition significant CP violation is found in the pi(+)pi S- wave at low invariant mass. The presence of CP violation related to interference between the pi(+)pi S- wave and the P wave B+ -> rho(770)(0)pi(+) amplitude is also established; this causes large local asymmetries but cancels when integrated over the phase space of the decay. The results provide both qualitative and quantitative new insights into CP -violation effects in hadronic B decays.  
  Address [Bediaga, I.; Torres, M. Cruz; De Miranda, J. M.; Gomes, A.; Massafferri, A.; Rodriguez, J. Molina; dos Reis, A. C.; Lavra, L. Soares; Tourinho Jadallah Aoude, R.] CBPF, Rio De Janeiro, Brazil, Email: jiayin.sun@cern.ch  
  Corporate Author Thesis  
  Publisher Amer Physical Soc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9007 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000508455800003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 4261  
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Author ANTARES Collaboration (Albert, A. et al); Alves, S.; Carretero, V.; Colomer, M.; Hernandez-Rey, J.J.; Khan-Chowdhury, N.R.; Manczak, J.; Pieterse, C.; Salesa Greus, F.; Zornoza, J.D.; Zuñiga, J. url  doi
openurl 
  Title Search for Neutrinos from the Tidal Disruption Events AT2019dsg and AT2019fdr with the ANTARES Telescope Type Journal Article
  Year 2021 Publication Astrophysical Journal Abbreviated Journal Astrophys. J.  
  Volume 920 Issue 1 Pages 50 - 6pp  
  Keywords  
  Abstract (up) On 2019 October 1, the IceCube Collaboration detected a muon track neutrino with a high probability of being of astrophysical origin, IC191001A. After a few hours, the tidal disruption event (TDE) AT2019dsg, observed by the Zwicky Transient Facility (ZTF), was indicated as the most likely counterpart of the IceCube track. More recently, the follow-up campaign of the IceCube alerts by ZTF suggested a second TDE, AT2019fdr, as a promising counterpart of another IceCube muon track candidate, IC200530A, detected on 2020 May 30. Here, these intriguing associations are followed-up by searching for neutrinos in the ANTARES detector from the directions of AT2019dsg and AT2019fdr using a time-integrated approach. As no significant evidence for space clustering is found in the ANTARES data, upper limits on the one-flavor neutrino flux and fluence are set.  
  Address [Albert, A.; Drouhin, D.; Huang, F.; Organokov, M.; Pradier, T.] Univ Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, France, Email: giulia.illuminati3@unibo.it  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0004-637x ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000706478500001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5001  
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Author Muñoz, E.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F. doi  openurl
  Title A spectral reconstruction algorithm for two-plane Compton cameras Type Journal Article
  Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 65 Issue 2 Pages 025011 - 17pp  
  Keywords Compton imaging; Compton camera; hadron therapy; image reconstruction  
  Abstract (up) One factor limiting the current applicability extent of hadron therapy is the lack of a reliable method for real time treatment monitoring. The use of Compton imaging systems as monitors requires the correct reconstruction of the distribution of prompt gamma productions during patient irradiation. In order to extract the maximum information from all the measurable events, we implemented a spectral reconstruction method that assigns to all events a probability of being either partial or total energy depositions. The method, implemented in a list-mode maximum likelihood expectation maximization algorithm, generates a four dimensional image in the joint spatial-spectral domain, in which the voxels containing the emission positions and energies are obtained. The analytical model used for the system response function is also employed to derive an analytical expression for the sensitivity, which is calculated via Monte Carlo integration. The performance of the method is evaluated through reconstruction of various experimental and simulated sources with different spatial and energy distributions. The results show that the proposed method can recover the spectral and spatial information simultaneously, but only under the assumption of ideal measurements. The analysis of the Monte Carlo simulations has led to the identification of two important degradation sources: the mispositioning of the gamma interaction point and the missing energy recorded in the interaction. Both factors are related to the high energy transferred to the recoil electrons, which can travel far from the interaction point and even escape the detector. These effects prevent the direct application of the current method in more realistic scenarios. Nevertheless, experimental point-like sources have been accurately reconstructed and the spatial distributions and spectral emission of complex simulated phantoms can be identified.  
  Address [Munoz, Enrique; Barrientos, Luis; Bernabeu, Jose; Borja-Lloret, Marina; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000520111400001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 4332  
Permanent link to this record
 

 
Author Verdera, A.; Torres-Sanchez, P.; Praena, J.; Porras, I. doi  openurl
  Title Study of the out-of-field dose from an accelerator-based neutron source for boron neutron capture therapy Type Journal Article
  Year 2024 Publication Applied Radiation and Isotopes Abbreviated Journal Appl. Radiat. Isot.  
  Volume 212 Issue Pages 111458 - 6pp  
  Keywords BNCT; Neutrons; Out-of-field; Equivalent dose; Ambient dose  
  Abstract (up) One important issue in Boron Neutron Capture Therapy is the delivered dose to the tissues outside the tumor. An international standard for light ion beam systems sets two recommended limits for out-of-field dose based on distance from the field edge: maximum absorbed dose from all radiation types shall not exceed 0.5 % of the maximum dose at distances 15 cm to 50 cm from the field edge. At distances > 50 cm from the field edge, the maximum absorbed dose shall not exceed 0.1 %. This paper is a continuation of our previous works focused on the design of an accelerator-based neutron source for BNCT. We already designed a novel Beam Shape Assembly which meets the IAEA criteria for BNCT treatments. Using this BSA, in the present work, we characterize by Monte Carlo simulations the dose outside the neutron field. The out-of-field dose has been assessed via estimates using the ambient and equivalent dose. Also the boron uptake in healthy tissues has been analyzed for the equivalent dose computation. It is concluded that our design for a future accelerator-based source for BNCT meets reasonably well the criteria defined from other forms of radiotherapy on both equivalent and effective dose outside the field.  
  Address [Verdera, Antonia; Praena, Javier; Porras, Ignacio] Univ Granada, Dept Atom Mol & Nucl Phys, Granada, Spain  
  Corporate Author Thesis  
  Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0969-8043 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001291259700001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 6231  
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