Abstract: Coherent elastic neutrino-nucleus scattering was first experimentally established five years ago by the COHERENT experiment using neutrinos from the spallation neutron source at Oak Ridge National Laboratory. The first evidence of observation of coherent elastic neutrino-nucleus scattering with reactor antineutrinos has now been reported by the Dresden-II reactor experiment, using a germanium detector. In this paper, we present constraints on a variety of beyond the Standard Model scenarios using the new Dresden-II data. In particular, we explore the constraints imposed on neutrino nonstandard interactions, neutrino magnetic moments, and several models with light scalar or light vector mediators. We also quantify the impact of their combination with COHERENT (CsI and Ar) data. In doing so, we highlight the synergies between spallation neutron source and nuclear reactor experiments regarding beyond the Standard Model searches, as well as the advantages of combining data obtained with different nuclear targets. We also study the possible signal from beyond the Standard Model scenarios due to elastic scattering off electrons (which would pass selection cuts of the COHERENT CsI and the Dresden-II experiments) and find more stringent constraints in certain parts of the parameter space than those obtained considering coherent elastic neutrino-nucleus scattering.

Abstract: Collapsing supermassive stars (M greater than or similar to 3 x 10(4) M-circle dot) at high redshifts can naturally provide seeds and explain the origin of the supermassive black holes observed in the centers of nearly all galaxies. During the collapse of supermassive stars, a burst of non-thermal neutrinos is generated with a luminosity that could greatly exceed that of a conventional core collapse supernova explosion. In this work, we investigate the extent to which the neutrinos produced in these explosions can be observed via coherent elastic neutrino-nucleus scattering (CEvNS). Large scale direct dark matter detection experiments provide particularly favorable targets. We find that upcoming O(100) tonne-scale experiments will be sensitive to the collapse of individual supermassive stars at distances as large as O(10) Mpc.

Abstract: Combined measurements of Higgs boson production cross sections and branching fractions arc presented. The combination is based on the analyses of the Higgs boson decay modes H -> gamma gamma, ZZ*, WW*, tau tau, b (b) over bar, μmu, searches for decays into invisible final states, and on measurements of off-shell Higgs boson production. Up to 79.8 fb(-1) of proton-proton collision data collected at root S = 13 TeV with the ATLAS detector are used. Results are presented for the gluon-gluon fusion and vector-boson fusion processes, and for associated production with vector bosons or top-quarks. The global signal strength is determined to be μ= 1.11(-0.08)(+0.09). The combined measurement yields an observed (expected) significance for the vector-boson fusion production process of 6.5 sigma (5.3 sigma). Measurements in kinematic regions defined within the simplified template cross section framework are also shown. The results are interpreted in terms of modifiers applied to the Standard Model couplings of the Higgs boson to other particles, and are used to set exclusion limits on parameters in two-Higgs-doublet models and in the simplified minimal supersynunetric Standard Model. No significant deviations from Standard Model predictions are observed.

Abstract: Compton Cameras are electronically collimated photon imagers suitable for sub-MeV to few MeV gamma-ray detection. Such features are desirable to enablein vivorange verification in hadron therapy, through the detection of secondary Prompt Gammas. A major concern with this technique is the poor image quality obtained when the incoming gamma-ray energy is unknown. Compton Cameras with more than two detector planes (multi-layer Compton Cameras) have been proposed as a solution, given that these devices incorporate more signal sequences of interactions to the conventional two interaction events. In particular, three interaction events convey more spectral information as they allow inferring directly the incident gamma-ray energy. A three-layer Compton Telescope based on continuous Lanthanum (III) Bromide crystals coupled to Silicon Photomultipliers is being developed at the IRIS group of IFIC-Valencia. In a previous work we proposed a spectral reconstruction algorithm for two interaction events based on an analytical model for the formation of the signal. To fully exploit the capabilities of our prototype, we present here an extension of the model for three interaction events. Analytical expressions of the sensitivity and the System Matrix are derived and validated against Monte Carlo simulations. Implemented in a List Mode Maximum Likelihood Expectation Maximization algorithm, the proposed model allows us to obtain four-dimensional (energy and position) images by using exclusively three interaction events. We are able to recover the correct spectrum and spatial distribution of gamma-ray sources when ideal data are employed. However, the uncertainties associated to experimental measurements result in a degradation when real data from complex structures are employed. Incorrect estimation of the incident gamma-ray interaction positions, and missing deposited energy associated with escaping secondaries, have been identified as the causes of such degradation by means of a detailed Monte Carlo study. As expected, our current experimental resolution and efficiency to three interaction events prevents us from correctly recovering complex structures of radioactive sources. However, given the better spectral information conveyed by three interaction events, we expect an improvement of the image quality of conventional Compton imaging when including such events. In this regard, future development includes the incorporation of the model assessed in this work to the two interaction events model in order to allow using simultaneously two and three interaction events in the image reconstruction.

Abstract: Compton cameras can offer advantages over gamma cameras for some applications, since they are well suited for multitracer imaging and for imaging high-energy radiotracers, such as those employed in radionuclide therapy. While in conventional clinical settings state-of-the-art Compton cameras cannot compete with well-established methods such as PET and SPECT, there are specific scenarios in which they can constitute an advantageous alternative. The combination of PET and Compton imaging can benefit from the improved resolution and sensitivity of current PET technology and, at the same time, overcome PET limitations in the use of multiple radiotracers. Such a system can provide simultaneous assessment of different radiotracers under identical conditions and reduce errors associated with physical factors that can change between acquisitions. Advances are being made both in instrumentation developments combining PET and Compton cameras for multimodal or three-gamma imaging systems, and in image reconstruction, addressing the challenges imposed by the combination of the two modalities or the new techniques. This review article summarizes the advances made in Compton cameras for medical imaging and their combination with PET.