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Llosa, G., & Rafecas, M. (2023). Hybrid PET/Compton-camera imaging: an imager for the next generation. Eur. Phys. J. Plus, 138(3), 214–19pp.
Abstract: Compton cameras can offer advantages over gamma cameras for some applications, since they are well suited for multitracer imaging and for imaging high-energy radiotracers, such as those employed in radionuclide therapy. While in conventional clinical settings state-of-the-art Compton cameras cannot compete with well-established methods such as PET and SPECT, there are specific scenarios in which they can constitute an advantageous alternative. The combination of PET and Compton imaging can benefit from the improved resolution and sensitivity of current PET technology and, at the same time, overcome PET limitations in the use of multiple radiotracers. Such a system can provide simultaneous assessment of different radiotracers under identical conditions and reduce errors associated with physical factors that can change between acquisitions. Advances are being made both in instrumentation developments combining PET and Compton cameras for multimodal or three-gamma imaging systems, and in image reconstruction, addressing the challenges imposed by the combination of the two modalities or the new techniques. This review article summarizes the advances made in Compton cameras for medical imaging and their combination with PET.
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Llosa, G. (2019). SiPM-based Compton cameras. Nucl. Instrum. Methods Phys. Res. A, 926, 148–152.
Abstract: Compton cameras have been developed for almost fifty years in various fields (astronomy, medical imaging, safety and industrial inspections, etc.), employing different types of detectors. Their potential use has gained renewed interest with the emergence of high light yield scintillator crystals and silicon photomultipliers (SiPMs). This combination provides good performance and operation simplicity at an affordable cost, raising again the interest in this type of systems. SiPM-based Compton cameras are being assessed for diverse applications with promising results.
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Lerendegui-Marco, J., Balibrea-Correa, J., Babiano-Suarez, V., Ladarescu, I., & Domingo-Pardo, C. (2022). Towards machine learning aided real-time range imaging in proton therapy. Sci Rep, 12(1), 2735–17pp.
Abstract: Compton imaging represents a promising technique for range verification in proton therapy treatments. In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by gamma-ray energies spanning up to 5-6 MeV, rather low gamma-ray emission yields and very intense neutron induced gamma-ray backgrounds. Our developments to cope with these three aspects are concomitant with those required in the field of hadron therapy, especially in terms of high efficiency for real-time monitoring, low sensitivity to neutron backgrounds and reliable performance at the high gamma-ray energies. We find that signal-to-background ratios can be appreciably improved with i-TED thanks to its light-weight design and the low neutron-capture cross sections of its LaCl3 crystals, when compared to other similar systems based on LYSO, CdZnTe or LaBr3. Its high time-resolution (CRT similar to 500 ps) represents an additional advantage for background suppression when operated in pulsed HT mode. Each i-TED Compton module features two detection planes of very large LaCl3 monolithic crystals, thereby achieving a high efficiency in coincidence of 0.2% for a point-like 1 MeV gamma-ray source at 5 cm distance. This leads to sufficient statistics for reliable image reconstruction with an array of four i-TED detectors assuming clinical intensities of 10(8) protons per treatment point. The use of a two-plane design instead of three-planes has been preferred owing to the higher attainable efficiency for double time-coincidences than for threefold events. The loss of full-energy events for high energy gamma-rays is compensated by means of machine-learning based algorithms, which allow one to enhance the signal-to-total ratio up to a factor of 2.
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Barenboim, G., Denton, P. B., & Oldengott, I. M. (2019). Constraints on inflation with an extended neutrino sector. Phys. Rev. D, 99(8), 083515–9pp.
Abstract: Constraints on inflationary models typically assume only the standard models of cosmology and particle physics. By extending the neutrino sector to include a new interaction with a light scalar mediator (m(phi) similar to MeV), it is possible to relax these constraints, in particular via opening up regions of the parameter space of the spectral index n(s). These new interactions can be probed at IceCube via interactions of astrophysical neutrinos with the cosmic neutrino background for nearly all of the relevant parameter space.
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ATLAS Collaboration(Aaboud, M. et al), Alvarez Piqueras, D., Aparisi Pozo, J. A., Bailey, A. J., Barranco Navarro, L., Cabrera Urban, S., et al. (2019). Constraints on mediator-based dark matter and scalar dark energy models using root s= 13 TeV pp collision data collected by the ATLAS detector. J. High Energy Phys., 05(5), 142–87pp.
Abstract: Constraints on selected mediator-based dark matter models and a scalar dark energy model using up to 37 fb(-1) = 13 TeV pp collision data collected by the ATLAS detector at the LHC during 2015-2016 are summarised in this paper. The results of experimental searches in a variety of final states are interpreted in terms of a set of spin-1 and spin-0 single-mediator dark matter simplified models and a second set of models involving an extended Higgs sector plus an additional vector or pseudo-scalar mediator. The searches considered in this paper constrain spin-1 leptophobic and leptophilic mediators, spin-0 colour-neutral and colour-charged mediators and vector or pseudo-scalar mediators embedded in extended Higgs sector models. In this case, also = 8 TeV pp collision data are used for the interpretation of the results. The results are also interpreted for the first time in terms of light scalar particles that could contribute to the accelerating expansion of the universe (dark energy).
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ATLAS Collaboration(Aad, G. et al), Amos, K. R., Aparisi Pozo, J. A., Bailey, A. J., Cabrera Urban, S., Cantero, J., et al. (2023). Constraints on the Higgs boson self-coupling from single- and double-Higgs production with the ATLAS detector using pp collisions at & RADIC;s=13 TeV. Phys. Lett. B, 843, 137745–20pp.
Abstract: Constraints on the Higgs boson self-coupling are set by combining double-Higgs boson analyses in the bb over bar bb over bar , bb over bar & tau;+& tau;- and bb over bar & gamma; & gamma; decay channels with single-Higgs boson analyses targeting the & gamma;& gamma;, Z Z*, W W *, & tau;+& tau;- and bb over bar decay channels. The data used in these analyses were recorded by the ATLAS detector at the LHC in proton-proton collisions at & RADIC;s = 13 TeV and correspond to an integrated luminosity of 126-139 fb-1. The combination of the double-Higgs analyses sets an upper limit of & mu;HH < 2.4 at 95% confidence level on the double-Higgs production cross-section normalised to its Standard Model prediction. Combining the single-Higgs and double-Higgs analyses, with the assumption that new physics affects only the Higgs boson self-coupling (& lambda;HHH), values outside the interval -0.4 < & kappa;& lambda; = (& lambda;HHH/& lambda;SM H H H ) < 6.3 are excluded at 95% confidence level. The combined single-Higgs and double-Higgs analyses provide results with fewer assumptions, by adding in the fit more coupling modifiers introduced to account for the Higgs boson interactions with the other Standard Model particles. In this relaxed scenario, the constraint becomes -1.4 < & kappa;& lambda; < 6.1 at 95% CL.
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Panes, B., Eckner, C., Hendriks, L., Caron, S., Dijkstra, K., Johannesson, G., et al. (2021). Identification of point sources in gamma rays using U-shaped convolutional neural networks and a data challenge. Astron. Astrophys., 656, A62–18pp.
Abstract: Context. At GeV energies, the sky is dominated by the interstellar emission from the Galaxy. With limited statistics and spatial resolution, accurately separating point sources is therefore challenging. Aims. Here we present the first application of deep learning based algorithms to automatically detect and classify point sources from gamma-ray data. For concreteness we refer to this approach as AutoSourceID. Methods. To detect point sources, we utilized U-shaped convolutional networks for image segmentation and k-means for source clustering and localization. We also explored the Centroid-Net algorithm, which is designed to find and count objects. Using two algorithms allows for a cross check of the results, while a combination of their results can be used to improve performance. The training data are based on 9.5 years of exposure from The Fermi Large Area Telescope (Fermi-LAT) and we used source properties of active galactic nuclei (AGNs) and pulsars (PSRs) from the fourth Fermi-LAT source catalog in addition to several models of background interstellar emission. The results of the localization algorithm are fed into a classification neural network that is trained to separate the three general source classes (AGNs, PSRs, and FAKE sources). Results. We compared our localization algorithms qualitatively with traditional methods and find them to have similar detection thresholds. We also demonstrate the robustness of our source localization algorithms to modifications in the interstellar emission models, which presents a clear advantage over traditional methods. The classification network is able to discriminate between the three classes with typical accuracy of similar to 70%, as long as balanced data sets are used in classification training. We published online our training data sets and analysis scripts and invite the community to join the data challenge aimed to improve the localization and classification of gamma-ray point sources.
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HAWC Collaboration(Alfaro, R. et al), & Salesa Greus, F. (2022). Validation of standardized data formats and tools for ground-level particle-based gamma-ray observatories. Astron. Astrophys., 667, A36–12pp.
Abstract: Context. Ground-based gamma-ray astronomy is still a rather young field of research, with strong historical connections to particle physics. This is why most observations are conducted by experiments with proprietary data and analysis software, as is usual in the particle physics field. However, in recent years, this paradigm has been slowly shifting toward the development and use of open-source data formats and tools, driven by upcoming observatories such as the Cherenkov Telescope Array (CTA). In this context, a community-driven, shared data format (the gamma-astro-data-format, or GADF) and analysis tools such as Gammapy and ctools have been developed. So far, these efforts have been led by the Imaging Atmospheric Cherenkov Telescope community, leaving out other types of ground-based gamma-ray instruments. Aims. We aim to show that the data from ground particle arrays, such as the High-Altitude Water Cherenkov (HAWC) observatory, are also compatible with the GADF and can thus be fully analyzed using the related tools, in this case, Gammapy. Methods. We reproduced several published HAWC results using Gammapy and data products compliant with GADF standard. We also illustrate the capabilities of the shared format and tools by producing a joint fit of the Crab spectrum including data from six different gamma-ray experiments. Results. We find excellent agreement with the reference results, a powerful confirmation of both the published results and the tools involved. Conclusions. The data from particle detector arrays such as the HAWC observatory can be adapted to the GADF and thus analyzed with Gammapy. A common data format and shared analysis tools allow multi-instrument joint analysis and effective data sharing. To emphasize this, a sample of Crab nebula event lists is made public with this paper. Because of the complementary nature of pointing and wide-field instruments, this synergy will be distinctly beneficial for the joint scientific exploitation of future observatories such as the Southern Wide-field Gamma-ray Observatory and CTA.
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Sanchis-Lozano, M. A., Melia, F., Lopez-Corredoira, M., & Sanchis-Gual, N. (2022). Missing large-angle correlations versus even-odd point-parity imbalance in the cosmic microwave background. Astron. Astrophys., 660, A121–10pp.
Abstract: Context. The existence of a maximum correlation angle (theta(max) & 60 greater than or similar to degrees) in the two-point angular temperature correlations of cosmic microwave background (CMB) radiation, measured by WMAP and Planck, stands in sharp contrast to the prediction of standard inflationary cosmology, in which the correlations should extend across the full sky (i.e., 180 degrees). The introduction of a hard lower cuto ff (k(min)) in the primordial power spectrum, however, leads naturally to the existence of theta(max). Among other cosmological anomalies detected in these data, an apparent dominance of odd-over-even parity multipoles has been seen in the angular power spectrum of the CMB. This feature, however, may simply be due to observational contamination in certain regions of the sky. Aims. In attempting to provide a more detailed assessment of whether this odd-over-even asymmetry is intrinsic to the CMB, we therefore proceed in this paper, first, to examine whether this odd-even parity imbalance also manifests itself in the angular correlation function and, second, to examine in detail the interplay between the presence of theta(max) and this observed anomaly. Methods. We employed several parity statistics and recalculated the angular correlation function for di fferent values of the cuto ff kmin in order to optimize the fit to the di fferent Planck 2018 data. Results. We find a phenomenological connection between these features in the data, concluding that both must be considered together in order to optimize the theoretical fit to the Planck 2018 data. Conclusions. This outcome is independent of whether the parity imbalance is intrinsic to the CMB, but if it is, the odd-over-even asymmetry would clearly point to the emergence of new physics.
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Aguilar, A. C., De Soto, F., Ferreira, M. N., Papavassiliou, J., Pinto-Gomez, F., Roberts, C. D., et al. (2023). Schwinger mechanism for gluons from lattice QCD. Phys. Lett. B, 841, 137906–8pp.
Abstract: Continuum and lattice analyses have revealed the existence of a mass-scale in the gluon two-point Schwinger function. It has long been conjectured that this expresses the action of a Schwinger mechanism for gauge boson mass generation in quantum chromodynamics (QCD). For such to be true, it is necessary and sufficient that a dynamically-generated, massless, colour-carrying, scalar gluon+gluon correlation emerges as a feature of the dressed three-gluon vertex. Working with results on elementary Schwinger functions obtained via the numerical simulation of lattice-regularised QCD, we establish with an extremely high level of confidence that just such a feature appears; hence, confirm the conjectured origin of the gluon mass scale.
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