| |
Records |
Links |
|
Author |
Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.L.; Thomson, R.M.; Verhaegen, F.; Vijande, J.; Ma, Y.Z.; Beaulieu, L. |
|
| |
Title |
A generic high-dose rate Ir-192 brachytherapy source for evaluation of model-based dose calculations beyond the TG-43 formalism |
Type |
Journal Article |
| |
Year |
2015 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
|
| |
Volume |
42 |
Issue |
6 |
Pages |
3048-3062 |
|
| |
Keywords |
Ir-192; HDR brachytherapy; Monte Carlo methods; model-based dose calculation; TG-186 |
|
| |
Abstract  |
Purpose: In order to facilitate a smooth transition for brachytherapy dose calculations from the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) formalism to model-based dose calculation algorithms (MBDCAs), treatment planning systems (TPSs) using a MBDCA require a set of well-defined test case plans characterized by Monte Carlo (MC) methods. This also permits direct dose comparison to TG-43 reference data. Such test case plans should be made available for use in the software commissioning process performed by clinical end users. To this end, a hypothetical, generic high-dose rate (HDR) Ir-192 source and a virtual water phantom were designed, which can be imported into a TPS. Methods: A hypothetical, generic HDR Ir-192 source was designed based on commercially available sources as well as a virtual, cubic water phantom that can be imported into any TPS in DICOM format. The dose distribution of the generic Ir-192 source when placed at the center of the cubic phantom, and away from the center under altered scatter conditions, was evaluated using two commercial MBDCAs [Oncentra (R) Brachy with advanced collapsed-cone engine (ACE) and BrachyVision AcuRos (TM)]. Dose comparisons were performed using state-of-the-art MC codes for radiation transport, including ALGEBRA, BrachyDose, GEANT4, MCNP5, MCNP6, and pENELopE2008. The methodologies adhered to recommendations in the AAPM TG-229 report on high-energy brachytherapy source dosimetry. TG-43 dosimetry parameters, an along-away dose-rate table, and primary and scatter separated (PSS) data were obtained. The virtual water phantom of (201)(3) voxels (1 mm sides) was used to evaluate the calculated dose distributions. Two test case plans involving a single position of the generic HDR Ir-192 source in this phantom were prepared: (i) source centered in the phantom and (ii) source displaced 7 cm laterally from the center. Datasets were independently produced by different investigators. MC results were then compared against dose calculated using TG-43 and MBDCA methods. Results: TG-43 and PSS datasets were generated for the generic source, the PSS data for use with the ACE algorithm. The dose-rate constant values obtained from seven MC simulations, performed independently using different codes, were in excellent agreement, yielding an average of 1.1109 +/- 0.0004 cGy/(h U) (k = 1, Type A uncertainty). MC calculated dose-rate distributions for the two plans were also found to be in excellent agreement, with differences within type A uncertainties. Differences between commercial MBDCA and MC results were test, position, and calculation parameter dependent. On average, however, these differences were within 1% for ACUROS and 2% for ACE at clinically relevant distances. Conclusions: A hypothetical, generic HDR Ir-192 source was designed and implemented in two commercially available TPSs employing different MBDCAs. Reference dose distributions for this source were benchmarked and used for the evaluation of MBDCA calculations employing a virtual, cubic water phantom in the form of a CT DICOM image series. The implementation of a generic source of identical design in all TPSs using MBDCAs is an important step toward supporting univocal commissioning procedures and direct comparisons between TPSs. |
|
| |
Address |
[Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Facundo.Ballester@uv.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Amer Assoc Physicists Medicine Amer Inst Physics |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0094-2405 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000356998300031 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
2315 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Ma, Y.Z.; Vijande, J.; Ballester, F.; Tedgren, A.C.; Granero, D.; Haworth, A.; Mourtada, F.; Fonseca, G.P.; Zourari, K.; Papagiannis, P.; Rivard, M.J.; Siebert, F.A.; Sloboda, R.S.; Smith, R.; Chamberland, M.J.P.; Thomson, R.M.; Verhaegen, F.; Beaulieu, L. |
|
| |
Title |
A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy |
Type |
Journal Article |
| |
Year |
2017 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
|
| |
Volume |
44 |
Issue |
11 |
Pages |
5961-5976 |
|
| |
Keywords |
Ir-192; HDR brachytherapy; model based dose calculation; Monte Carlo methods; shielded applicator; TG-186 |
|
| |
Abstract |
PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy. |
|
| |
Address |
[Ma, Yunzhi; Beaulieu, Luc] CHU Quebec, Dept Radio Oncol & Axe Oncol, Ctr Rech, Quebec City, PQ G1R 2J6, Canada, Email: yunzhi.Ma@crchuq.ulaval.ca |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Wiley |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0094-2405 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000414970800039 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
3370 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Trotta, R.; Johannesson, G.; Moskalenko, I.V.; Porter, T.A.; Ruiz de Austri, R.; Strong, A.W. |
|
| |
Title |
Constraints on Cosmic-Ray Propagation Models from a Global Bayesian Analysis |
Type |
Journal Article |
| |
Year |
2011 |
Publication |
Astrophysical Journal |
Abbreviated Journal |
Astrophys. J. |
|
| |
Volume |
729 |
Issue |
2 |
Pages |
106 - 16pp |
|
| |
Keywords |
astroparticle physics; cosmic rays; diffusion; Galaxy: general; ISM: general; methods: statistical |
|
| |
Abstract |
Research in many areas of modern physics such as, e. g., indirect searches for dark matter and particle acceleration in supernova remnant shocks rely heavily on studies of cosmic rays (CRs) and associated diffuse emissions (radio, microwave, X-rays, gamma-rays). While very detailed numerical models of CR propagation exist, a quantitative statistical analysis of such models has been so far hampered by the large computational effort that those models require. Although statistical analyses have been carried out before using semi-analytical models (where the computation is much faster), the evaluation of the results obtained from such models is difficult, as they necessarily suffer from many simplifying assumptions. The main objective of this paper is to present a working method for a full Bayesian parameter estimation for a numerical CR propagation model. For this study, we use the GALPROP code, the most advanced of its kind, which uses astrophysical information, and nuclear and particle data as inputs to self-consistently predict CRs, gamma-rays, synchrotron, and other observables. We demonstrate that a full Bayesian analysis is possible using nested sampling and Markov Chain Monte Carlo methods (implemented in the SuperBayeS code) despite the heavy computational demands of a numerical propagation code. The best-fit values of parameters found in this analysis are in agreement with previous, significantly simpler, studies also based on GALPROP. |
|
| |
Address |
[Trotta, R.] Univ London Imperial Coll Sci Technol & Med, Astrophys Grp, Blackett Lab, London SW7 2AZ, England |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Iop Publishing Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0004-637x |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000288608700029 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
541 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
ATLAS Collaboration (Aaboud, M. et al); Alvarez Piqueras, D.; Bailey, A.J.; Barranco Navarro, L.; Cabrera Urban, S.; Castillo Gimenez, V.; Cerda Alberich, L.; Costa, M.J.; Escobar, C.; Estrada Pastor, O.; Ferrer, A.; Fiorini, L.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Higon-Rodriguez, E.; Jimenez Pena, J.; Lacasta, C.; Lozano Bahilo, J.J.; Madaffari, D.; Mamuzic, J.; Marti-Garcia, S.; Melini, D.; Mitsou, V.A.; Pedraza Lopez, S.; Rodriguez Bosca, S.; Rodriguez Rodriguez, D.; Salt, J.; Soldevila, U.; Sanchez, J.; Valero, A.; Valls Ferrer, J.A.; Vos, M. |
|
| |
Title |
Comparison between simulated and observed LHC beam backgrounds in the ATLAS experiment at E-beam=4 TeV |
Type |
Journal Article |
| |
Year |
2018 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
|
| |
Volume |
13 |
Issue |
|
Pages |
P12006 - 41pp |
|
| |
Keywords |
Accelerator modelling and simulations (multi-particle dynamics; single-particle dynamics); Radiation calculations; Simulation methods and programs |
|
| |
Abstract |
Results of dedicated Monte Carlo simulations of beam-induced background (BIB) in the ATLAS experiment at the Large Hadron Collider (LHC) are presented and compared with data recorded in 2012. During normal physics operation this background arises mainly from scattering of the 4 TeV protons on residual gas in the beam pipe. Methods of reconstructing the BIB signals in the ATLAS detector, developed and implemented in the simulation chain based on the FLUKA Monte Carlo simulation package, are described. The interaction rates are determined from the residual gas pressure distribution in the LHC ring in order to set an absolute scale on the predicted rates of BIB so that they can be compared quantitatively with data. Through these comparisons the origins of the BIB leading to different observables in the ATLAS detectors are analysed. The level of agreement between simulation results and BIB measurements by ATLAS in 2012 demonstrates that a good understanding of the origin of BIB has been reached. |
|
| |
Address |
[Duvnjak, D.; Jackson, P.; Oliver, J. L.; Petridis, A.; Qureshi, A.; Sharma, A. S.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Iop Publishing Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1748-0221 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000452068100002 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
3826 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Ortiz Arciniega, J.L.; Carrio, F.; Valero, A. |
|
| |
Title |
FPGA implementation of a deep learning algorithm for real-time signal reconstruction in particle detectors under high pile-up conditions |
Type |
Journal Article |
| |
Year |
2019 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
|
| |
Volume |
14 |
Issue |
|
Pages |
P09002 - 13pp |
|
| |
Keywords |
Data processing methods; Pattern recognition; cluster finding; calibration and fitting methods; Simulation methods and programs |
|
| |
Abstract |
The analog signals generated in the read-out electronics of particle detectors are shaped prior to the digitization in order to improve the signal to noise ratio (SNR). The real amplitude of the analog signal is then obtained using digital filters, which provides information about the energy deposited in the detector. The classical digital filters have a good performance in ideal situations with Gaussian electronic noise and no pulse shape distortion. However, high-energy particle colliders, such as the Large Hadron Collider (LHC) at CERN, can produce multiple simultaneous events, which produce signal pileup. The performance of classical digital filters deteriorates in these conditions since the signal pulse shape gets distorted. In addition, this type of experiments produces a high rate of collisions, which requires high throughput data acquisitions systems. In order to cope with these harsh requirements, new read-out electronics systems are based on high-performance FPGAs, which permit the utilization of more advanced real-time signal reconstruction algorithms. In this paper, a deep learning method is proposed for real-time signal reconstruction in high pileup particle detectors. The performance of the new method has been studied using simulated data and the results are compared with a classical FIR filter method. In particular, the signals and FIR filter used in the ATLAS Tile Calorimeter are used as benchmark. The implementation, resources usage and performance of the proposed Neural Network algorithm in FPGA are also presented. |
|
| |
Address |
[Ortiz Arciniega, J. L.] Univ Valencia, Avinguda Univ S-N, Burjassot, Spain, Email: orarjo@alumni.uv.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Iop Publishing Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1748-0221 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000486990000002 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
no |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
4150 |
|
| Permanent link to this record |
