Candela-Juan, C., Niatsetski, Y., van der Laarse, R., Granero, D., Ballester, F., Perez-Calatayud, J., et al. (2016). Design and characterization of a new high-dose-rate brachytherapy Valencia applicator for larger skin lesions. Med. Phys., 43(4), 1639–1648.
Abstract: Purpose: The aims of this study were (i) to design a new high-dose-rate (HDR) brachytherapy applicator for treating surface lesions with planning target volumes larger than 3 cm in diameter and up to 5 cm in size, using the microSelectron-HDR or Flexitron afterloader (Elekta Brachytherapy) with a Ir-192 source; (ii) to calculate by means of the Monte Carlo (MC) method the dose distribution for the new applicator when it is placed against a water phantom; and (iii) to validate experimentally the dose distributions in water. Methods: The PENELOPE2008 MC code was used to optimize dwell positions and dwell times. Next, the dose distribution in a water phantom and the leakage dose distribution around the applicator were calculated. Finally, MC data were validated experimentally for a 192Ir mHDR-v2 source by measuring (i) dose distributions with radiochromic EBT3 films (ISP); (ii) percentage depth-dose (PDD) curve with the parallel-plate ionization chamber Advanced Markus (PTW); and (iii) absolute dose rate with EBT3 films and the PinPoint T31016 (PTW) ionization chamber. Results: The new applicator is made of tungsten alloy (Densimet) and consists of a set of interchangeable collimators. Three catheters are used to allocate the source at prefixed dwell positions with preset weights to produce a homogenous dose distribution at the typical prescription depth of 3 mm in water. The same plan is used for all available collimators. PDD, absolute dose rate per unit of air kerma strength, and off-axis profiles in a cylindrical water phantom are reported. These data can be used for treatment planning. Leakage around the applicator was also scored. The dose distributions, PDD, and absolute dose rate calculated agree within experimental uncertainties with the doses measured: differences of MC data with chamber measurements are up to 0.8% and with radiochromic films are up to 3.5%. Conclusions: The new applicator and the dosimetric data provided here will be a valuable tool in clinical practice, making treatment of large skin lesions simpler, faster, and safer. Also the dose to surrounding healthy tissues is minimal.
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Granero, D., Candela-Juan, C., Vijande, J., Ballester, F., Perez-Calatayud, J., Jacob, D., et al. (2016). Technical Note: Dosimetry of Leipzig and Valencia applicators without the plastic cap. Med. Phys., 43(5), 2087–4pp.
Abstract: Purpose: High dose rate (HDR) brachytherapy for treatment of small skin lesions using the Leipzig and Valencia applicators is a widely used technique. These applicators are equipped with an attachable plastic cap to be placed during fraction delivery to ensure electronic equilibrium and to prevent secondary electrons from reaching the skin surface. The purpose of this study is to report on the dosimetric impact of the cap being absent during HDR fraction delivery, which has not been explored previously in the literature. Methods: GEANT4 Monte Carlo simulations (version 10.0) have been performed for the Leipzig and Valencia applicators with and without the plastic cap. In order to validate the Monte Carlo simulations, experimental measurements using radiochromic films have been done. Results: Dose absorbed within 1 mm of the skin surface increases by a factor of 1500% for the Leipzig applicators and of 180% for the Valencia applicators. Deeper than 1 mm, the overdosage flattens up to a 10% increase. Conclusions: Differences of treating with or without the plastic cap are significant. Users must check always that the plastic cap is in place before any treatment in order to avoid overdosage of the skin. Prior to skin HDR fraction delivery, the timeout checklist should include verification of the cap placement. (C) 2016 American Association of Physicists in Medicine.
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ATLAS Collaboration(Aad, G. et al), Cabrera Urban, S., Castillo Gimenez, V., Costa, M. J., Ferrer, A., Fiorini, L., et al. (2016). Centrality, rapidity, and transverse momentum dependence of isolated prompt photon production in lead-lead collisions at root S-NN=2.76 TeV measured with the ATLAS detector. Phys. Rev. C, 93(3), 034914–28pp.
Abstract: Prompt photon production in root S-NN = 2.76-TeV Pb + Pb collisions has been measured by the ATLAS experiment at the Large Hadron Collider using data collected in 2011 with an integrated luminosity of 0.14 nb(-1). Inclusive photon yields, scaled by the mean nuclear thickness function, are presented as a function of collision centrality and transverse momentum in two pseudorapidity intervals, vertical bar eta vertical bar < 1.37 and 1.52 <= vertical bar eta vertical bar < 2.37. The scaled yields in the two pseudorapidity intervals, as well as the ratios of the forward yields to those at midrapidity, are compared to the expectations from next-to-leading-order perturbative QCD (pQCD) calculations. The measured cross sections agree well with the predictions for proton-proton collisions within statistical and systematic uncertainties. Both the yields and the ratios are also compared to two other pQCD calculations, one which uses the isospin content appropriate to colliding lead nuclei and another which includes nuclear modifications to the nucleon parton distribution functions.
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LHCb Collaboration(Aaij, R. et al), Martinez-Vidal, F., Oyanguren, A., Ruiz Valls, P., & Sanchez Mayordomo, C. (2016). Measurements of prompt charm production cross-sections in pp collisions at root s=13 TeV. J. High Energy Phys., 03(3), 159–43pp.
Abstract: Production cross-sections of prompt charm mesons are measured with the first data from pp collisions at the LHC at a centre-of-mass energy of 13 TeV. The data sample corresponds to an integrated luminosity of 4.98 +/- 0.19 pb(-1) collected by the LHCb experiment. The production cross-sections of D-0, D+, D (s) (+) , and D*+ mesons are measured in bins of charm meson transverse momentum, p(T), and rapidity, y, and cover the range 0 < p(T) < 15GeV/c and 2.0 < y < 4.5. The inclusive cross-sections for the four mesons, including charge conjugation, within the range of 1 < p(T) < 8 GeV/c are found to be sigma(pp -> D-0 X) = 2460 +/- 3 +/- 130 μb sigma(pp -> D+ X) = 1000 +/- 3 +/- 110 μb sigma(pp -> Ds+X) = 460 +/- 13 +/- 100 μb sigma(pp -> D*+ X) = 880 +/- 5 +/- 140 μb where the uncertainties are due to statistical and systematic uncertainties, respectively.
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Liddick, S. N., Spyrou, A., Crider, B. P., Naqvi, F., Larsen, A. C., Guttormsen, M., et al. (2016). Experimental Neutron Capture Rate Constraint Far from Stability. Phys. Rev. Lett., 116(24), 242502–6pp.
Abstract: Nuclear reactions where an exotic nucleus captures a neutron are critical for a wide variety of applications, from energy production and national security, to astrophysical processes, and nucleosynthesis. Neutron capture rates are well constrained near stable isotopes where experimental data are available; however, moving far from the valley of stability, uncertainties grow by orders of magnitude. This is due to the complete lack of experimental constraints, as the direct measurement of a neutron-capture reaction on a short-lived nucleus is extremely challenging. Here, we report on the first experimental extraction of a neutron capture reaction rate on Ni-69, a nucleus that is five neutrons away from the last stable isotope of Ni. The implications of this measurement on nucleosynthesis around mass 70 are discussed, and the impact of similar future measurements on the understanding of the origin of the heavy elements in the cosmos is presented.
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