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Author Piriz, G.H.; Gonzalez-Sprinberg, G.A.; Ballester, F.; Vijande, J. doi  openurl
  Title Dosimetry of Large Field Valencia applicators for Cobalt-60-based brachytherapy Type Journal Article
  Year 2024 Publication Medical Physics Abbreviated Journal Med. Phys.  
  Volume Issue Pages 5pp  
  Keywords dosimetry; Monte Carlo; skin brachytherapy; Valencia applicators  
  Abstract (up) BackgroundNon-melanoma skin cancer is one of the most common types of cancer and one of the main approaches is brachytherapy. For small lesions, the treatment of this cancer with brachytherapy can be done with two commercial applicators, one of these is the Large Field Valencia Applicators (LFVA).PurposeThe aim of this study is to test the capabilities of the LFVA to use clinically 60Co sources instead of the 192Ir ones. This study was designed for the same dwell positions and weights for both sources.MethodsThe Penelope Monte Carlo code was used to evaluate dose distribution in a water phantom when a 60Co source is considered. The LFVA design and the optimized dwell weights reported for the case of 192Ir are maintained with the only exception of the dwell weight of the central position, that was increased. 2D dose distributions, field flatness, symmetry and the leakage dose distribution around the applicator were calculated.ResultsWhen comparing the dose distributions of both sources, field flatness and symmetry remain unchanged. The only evident difference is an increase of the penumbra regions for all depths when using the 60Co source. Regarding leakage, the maximum dose within the air volume surrounding the applicator is in the order of 20% of the prescription dose for the 60Co source, but it decreases to less than 5% at about 1 cm distance.ConclusionsFlatness and symmetry remains unaltered as compared with 192Ir sources, while an increase in leakage has been observed. This proves the feasibility of using the LFVA in a larger range of clinical applications.  
  Address [Piriz, Gustavo H.; Gonzalez-Sprinberg, Gabriel A.] Univ Republica, Fac Sci, Med Phys Unit, Montevideo, Uruguay, Email: ghpiriz@gmail.com  
  Corporate Author Thesis  
  Publisher Wiley Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0094-2405 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001187737100001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 6011  
Permanent link to this record
 

 
Author D'Auria, G. et al; Gonzalez-Iglesias, D.; Gimeno, B.; Pereira, D.E. doi  openurl
  Title The CompactLight Design Study Type Journal Article
  Year 2024 Publication European Physical Journal-Special Topics Abbreviated Journal Eur. Phys. J.-Spec. Top.  
  Volume Issue Pages 1-208  
  Keywords  
  Abstract (up) CompactLight is a Design Study funded by the European Union under the Horizon 2020 research and innovation funding programme, with Grant Agreement No. 777431. CompactLight was conducted by an International Collaboration of 23 international laboratories and academic institutions, three private companies, and five third parties. The project, which started in January 2018 with a duration of 48 months, aimed to design an innovative, compact, and cost-effective hard X-ray FEL facility complemented by a soft X-ray source to pave the road for future compact accelerator-based facilities. The result is an accelerator that can be operated at up to 1 kHz pulse repetition rate, beyond today's state of the art, using the latest concepts for high brightness electron photoinjectors, very high gradient accelerating structures in X-band, and novel short-period undulators. In this report, we summarize the main deliverable of the project: the CompactLight Conceptual Design Report, which overviews the current status of the design and addresses the main technological challenges.  
  Address [D'Auria, G.; Danailov, M.; Mitri, S. Di; Ferianis, M.; Gioppo, R.; Rochow, R.; Tabacco, C.; Zangrando, M.] Elettra Sincrotrone Trieste SCpA, AREA Sci Pk, I-34149 Trieste, Italy, Email: gerardo.dauria@elettra.eu  
  Corporate Author Thesis  
  Publisher Springer Heidelberg Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1951-6355 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001198683900001 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 6122  
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Author Navarro-Salas, J. url  doi
openurl 
  Title Black holes, conformal symmetry, and fundamental fields Type Journal Article
  Year 2024 Publication Classical and Quantum Gravity Abbreviated Journal Class. Quantum Gravity  
  Volume 41 Issue 8 Pages 085003 - 14pp  
  Keywords black holes; horizons; singularities; conformal symmetry; quantum fields; Standard Model  
  Abstract (up) Cosmic censorship protects the outside world from black hole singularities and paves the way for assigning entropy to gravity at the event horizons. We point out a tension between cosmic censorship and the quantum backreacted geometry of Schwarzschild black holes, induced by vacuum polarization and driven by the conformal anomaly. A similar tension appears for the Weyl curvature hypothesis at the Big Bang singularity. We argue that the requirement of exact conformal symmetry resolves both conflicts and has major implications for constraining the set of fundamental constituents of the Standard Model.  
  Address [Navarro-Salas, Jose] Univ Valencia, Dept Fis Teor, IFIC, CSIC, E-46100 Burjassot, Valencia, Spain, Email: jnavarro@ific.uv.es  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0264-9381 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001187435100001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 6029  
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Author Balaudo, A.; Calore, F.; De Romeri, V.; Donato, F. url  doi
openurl 
  Title NAJADS: a self-contained framework for the direct determination of astrophysical J-factors Type Journal Article
  Year 2024 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.  
  Volume 02 Issue 2 Pages 001 - 33pp  
  Keywords dark matter simulations; dark matter theory; dark matter detectors  
  Abstract (up) Cosmological simulations play a pivotal role in understanding the properties of the dark matter (DM) distribution in both galactic and galaxy -cluster environments. The characterization of DM structures is crucial for informing indirect DM searches, aiming at the detection of the annihilation (or decay) products of DM particles. A fundamental quantity in these analyses is the astrophysical J -factor. In the DM phenomenology community, J -factors are typically computed through the semi -analytical modelling of the DM mass distribution, which is affected by large uncertainties. With the scope of addressing and possibly reducing these uncertainties, we present NAJADS, a self-contained framework to derive the DM J -factor directly from the raw simulations data. We show how this framework can be used to compute all -sky maps of the J -factor, automatically accounting for the complex 3D structure of the simulated halos and for the boosting of the signal due to the density fluctuations along the line of sight. After validating our code, we present a proof -of -concept application of NAJADS to a realistic halo from the IllustrisTNG suite, and exploit it to make a thorough comparison between our numerical approach and traditional semi -analytical methods. JCAP02(2024)001  
  Address [Balaudo, Anna] Leiden Univ, Leiden Observ, POB 9513, NL-2300 RA Leiden, Netherlands, Email: balaudo@strw.leidenuniv.nl;  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1475-7516 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001182021200006 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 6018  
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Author Wang, D.; Mena, O. url  doi
openurl 
  Title Robust analysis of the growth of structure Type Journal Article
  Year 2024 Publication Physical Review D Abbreviated Journal Phys. Rev. D  
  Volume 109 Issue 8 Pages 083539 - 18pp  
  Keywords  
  Abstract (up) Current cosmological tensions show that it is crucial to test the predictions from the canonical ACDM paradigm at different cosmic times. One very appealing test of structure formation in the Universe is the growth rate of structure in our universe f, usually parametrized via the growth index gamma, with f equivalent to Omega(m)(a)gamma and gamma similar or equal to 0.55 in the standard ACDM case. Recent studies have claimed a suppression of the growth of structure from a variety of cosmological observations, characterized by gamma > 0.55. By employing different self-consistent growth parametrizations schemes, we show here that gamma < 0.55, obtaining instead an enhanced growth of structure today. This preference reaches the 3 sigma significance using cosmic microwave background observations, supernova Ia and baryon acoustic oscillation measurements. The addition of cosmic microwave background lensing data relaxes such a preference to the 2 sigma level, since a larger lensing effect can always be compensated with a smaller structure growth, or, equivalently, with gamma > 0.55. We have also included the lensing amplitude AL as a free parameter in our data analysis, showing that the preference for AL > 1 still remains, except for some particular parametrizations when lensing observations are included. We also do not find any significant preference for an oscillatory dependence of AL, AL + Am sin l. To further reassess the effects of a nonstandard growth, we have computed by means of N-body simulations the dark matter density fields, the dark matter halo mass functions and the halo density profiles for different values of gamma. Future observations from the Square Kilometer Array, reducing by a factor of 3 the current errors on the gamma parameter, further confirm or refute with a strong statistical significance the deviation of the growth index from its standard value.  
  Address [Wang, Deng; Mena, Olga] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Paterna, Spain, Email: dengwang@ific.uv.es;  
  Corporate Author Thesis  
  Publisher Amer Physical Soc Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2470-0010 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001224750700005 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 6130  
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