Records |
Author |
Torres-Espallardo, I.; Diblen, F.; Rohling, H.; Solevi, P.; Gillam, J.; Watts, D.; Espana, S.; Vandenberghe, S.; Fiedler, F.; Rafecas, M. |
Title |
Evaluation of resistive-plate-chamber-based TOF-PET applied to in-beam particle therapy monitoring |
Type |
Journal Article |
Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume |
60 |
Issue |
9 |
Pages |
N187-N208 |
Keywords |
PET; in-beam; RPC; particle therapy; TOF; range deviation; partial-ring |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Particle therapy is a highly conformal radiotherapy technique which reduces the dose deposited to the surrounding normal tissues. In order to fully exploit its advantages, treatment monitoring is necessary to minimize uncertainties related to the dose delivery. Up to now, the only clinically feasible technique for the monitoring of therapeutic irradiation with particle beams is Positron Emission Tomography (PET). In this work we have compared a Resistive Plate Chamber (RPC)-based PET scanner with a scintillation-crystal-based PET scanner for this application. In general, the main advantages of the RPC-PET system are its excellent timing resolution, low cost, and the possibility of building large area systems. We simulated a partial-ring scannerbeam monitoring, which has an intrinsically low positron yield compared to diagnostic PET. In addition, for in-beam PET there is a further data loss due to the partial ring configuration. In order to improve the performance of the RPC-based scanner, an improved version of the RPC detector (modifying the thickness of the gas and glass layers), providing a larger sensitivity, has been simulated and compared with an axially extended version of the crystal-based device. The improved version of the RPC shows better performance than the prototype, but the extended version of the crystal-based PET outperforms all other options. based on an RPC prototype under construction within the Fondazione per Adroterapia Oncologica (TERA). For comparison with the crystal-based PET scanner we have chosen the geometry of a commercially available PET scanner, the Philips Gemini TF. The coincidence time resolution used in the simulations takes into account the current achievable values as well as expected improvements of both technologies. Several scenarios (including patient data) have been simulated to evaluate the performance of different scanners. Initial results have shown that the low sensitivity of the RPC hampers its application to hadron |
Address |
[Torres-Espallardo, I.; Solevi, P.; Gillam, J.; Rafecas, M.] UV, CSIC, Inst Fis Corpuscular IFIC, E-46071 Valencia, Spain, Email: irene.torres@uv.es |
Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000354104700003 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
2227 |
Permanent link to this record |
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Author |
Alimena, J. et al; Hirsch, M.; Mamuzic, J.; Mitsou, V.A.; Santra, A. |
Title |
Searching for long-lived particles beyond the Standard Model at the Large Hadron Collider |
Type |
Journal Article |
Year |
2020 |
Publication |
Journal of Physics G |
Abbreviated Journal |
J. Phys. G |
Volume |
47 |
Issue |
9 |
Pages |
090501 - 226pp |
Keywords |
beyond the Standard Model; long-lived particles; Large Hadron Collider; high-luminosity LHC; collider phenomenology; high-energy collider experiments |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Particles beyond the Standard Model (SM) can generically have lifetimes that are long compared to SM particles at the weak scale. When produced at experiments such as the Large Hadron Collider (LHC) at CERN, these long-lived particles (LLPs) can decay far from the interaction vertex of the primary proton-proton collision. Such LLP signatures are distinct from those of promptly decaying particles that are targeted by the majority of searches for new physics at the LHC, often requiring customized techniques to identify, for example, significantly displaced decay vertices, tracks with atypical properties, and short track segments. Given their non-standard nature, a comprehensive overview of LLP signatures at the LHC is beneficial to ensure that possible avenues of the discovery of new physics are not overlooked. Here we report on the joint work of a community of theorists and experimentalists with the ATLAS, CMS, and LHCb experiments-as well as those working on dedicated experiments such as MoEDAL, milliQan, MATHUSLA, CODEX-b, and FASER-to survey the current state of LLP searches at the LHC, and to chart a path for the development of LLP searches into the future, both in the upcoming Run 3 and at the high-luminosity LHC. The work is organized around the current and future potential capabilities of LHC experiments to generally discover new LLPs, and takes a signature-based approach to surveying classes of models that give rise to LLPs rather than emphasizing any particular theory motivation. We develop a set of simplified models; assess the coverage of current searches; document known, often unexpected backgrounds; explore the capabilities of proposed detector upgrades; provide recommendations for the presentation of search results; and look towards the newest frontiers, namely high-multiplicity 'dark showers', highlighting opportunities for expanding the LHC reach for these signals. |
Address |
[Alimena, Juliette; Hill, Christopher S.] Ohio State Univ, Dept Phys, 191 W Woodruff Ave, Columbus, OH 43210 USA, Email: juliette.alimena@cern.ch; |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0954-3899 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000570614200001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
4535 |
Permanent link to this record |
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Author |
Mena, O.; Razzaque, S.; Villaescusa-Navarro, F. |
Title |
Signatures of photon and axion-like particle mixing in the gamma-ray burst jet |
Type |
Journal Article |
Year |
2011 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
Volume |
02 |
Issue |
2 |
Pages |
030 - 16pp |
Keywords |
axions; magnetic fields; gamma ray bursts theory; gamma ray burst experiments |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Photons couple to Axion-Like Particles (ALPs) or more generally to any pseudo Nambu-Goldstone boson in the presence of an external electromagnetic field. Mixing between photons and ALPs in the strong magnetic field of a Gamma-Ray Burst (GRB) jet during the prompt emission phase can leave observable imprints on the gamma-ray polarization and spectrum. Mixing in the intergalactic medium is not expected to modify these signatures for ALP mass > 10(-14) eV and/or for < nG magnetic field. We show that the depletion of photons due to conversion to ALPs changes the linear degree of polarization from the values predicted by the synchrotron model of gamma ray emission. We also show that when the magnetic field orientation in the propagation region is perpendicular to the field orientation in the production region, the observed synchrotron spectrum becomes steeper than the theoretical prediction and as detected in a sizable fraction of GRB sample. Detection of the correlated polarization and spectral signatures from these steep-spectrum GRBs by gamma-ray polarimeters can be a very powerful probe to discover ALPs. Measurement of gamma-ray polarization from GRBs in general, with high statistics, can also be useful to search for ALPs. |
Address |
[Mena, Olga; Villaescusa-Navarro, F.] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain, Email: omena@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000287859800031 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
559 |
Permanent link to this record |
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Author |
AbdusSalam, S.S. et al; Eberhardt, O. |
Title |
Simple and statistically sound recommendations for analysing physical theories |
Type |
Journal Article |
Year |
2022 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
Volume |
85 |
Issue |
5 |
Pages |
052201 - 11pp |
Keywords |
particle physics; statistics; methodology |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Physical theories that depend on many parameters or are tested against data from many different experiments pose unique challenges to statistical inference. Many models in particle physics, astrophysics and cosmology fall into one or both of these categories. These issues are often sidestepped with statistically unsound ad hoc methods, involving intersection of parameter intervals estimated by multiple experiments, and random or grid sampling of model parameters. Whilst these methods are easy to apply, they exhibit pathologies even in low-dimensional parameter spaces, and quickly become problematic to use and interpret in higher dimensions. In this article we give clear guidance for going beyond these procedures, suggesting where possible simple methods for performing statistically sound inference, and recommendations of readily-available software tools and standards that can assist in doing so. Our aim is to provide any physicists lacking comprehensive statistical training with recommendations for reaching correct scientific conclusions, with only a modest increase in analysis burden. Our examples can be reproduced with the code publicly available at Zenodo. |
Address |
[AbdusSalam, Shehu S.; Fowlie, Andrew] Shahid Beheshti Univ, Dept Phys, Tehran, Iran, Email: andrew.j.fowlie@njnu.edu.cn |
Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0034-4885 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000791574900001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5221 |
Permanent link to this record |
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Author |
T2K Collaboration (Abe, K. et al); Cervera-Villanueva, A.; Escudero, L.; Gomez-Cadenas, J.J.; Hansen, C.; Monfregola, L.; Sorel, M.; Stamoulis, P. |
Title |
Measurements of the T2K neutrino beam properties using the INGRID on-axis near detector |
Type |
Journal Article |
Year |
2012 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
Volume |
694 |
Issue |
|
Pages |
211-223 |
Keywords |
Neutrino oscillation; T2K; Neutrino beam; Neutrino detector; Extruded scintillator; Wavelength shifting fiber |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Precise measurement of neutrino beam direction and intensity was achieved based on a new concept with modularized neutrino detectors. INGRID (Interactive Neutrino GRID) is an on-axis near detector for the T2K long baseline neutrino oscillation experiment. INGRID consists of 16 identical modules arranged in horizontal and vertical arrays around the beam center. The module has a sandwich structure of iron target plates and scintillator trackers. INGRID directly monitors the muon neutrino beam profile center and intensity using the number of observed neutrino events in each module. The neutrino beam direction is measured with accuracy better than 0.4 mrad from the measured profile center. The normalized event rate is measured with 4% precision. (C) 2012 Elsevier B.V. All rights reserved. |
Address |
[Gomi, S.; Ichikawa, A. K.; Ieki, K.; Ikeda, M.; Kawamuko, H.; Kikawa, T.; Kubo, H.; Kubota, J.; Kurimoto, Y.; Litchfield, R. P.; Matsuoka, K.; Minamino, A.; Murakami, A.; Nagai, N.; Nakaya, T.; Nitta, K.; Nobuhara, T.; Otani, M.; Suzuki, K.; Taguchi, M.; Takahashi, S.; Yamauchi, T.] Kyoto Univ, Dept Phys, Kyoto 606, Japan, Email: masashi.o@scphys.kyoto-u.ac.jp |
Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000311020500031 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
1239 |
Permanent link to this record |
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Author |
Falkowski, A.; Gonzalez-Alonso, M.; Naviliat-Cuncic, O. |
Title |
Comprehensive analysis of beta decays within and beyond the Standard Model |
Type |
Journal Article |
Year |
2021 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
Volume |
04 |
Issue |
4 |
Pages |
126 - 36pp |
Keywords |
Effective Field Theories; Beyond Standard Model; Quark Masses and SM Parameters |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Precision measurements in allowed nuclear beta decays and neutron decay are reviewed and analyzed both within the Standard Model and looking for new physics. The analysis incorporates the most recent experimental and theoretical developments. The results are interpreted in terms of Wilson coefficients describing the effective interactions between leptons and nucleons (or quarks) that are responsible for beta decay. New global fits are performed incorporating a comprehensive list of precision measurements in neutron decay, superallowed 0(+)-> 0(+) transitions, and other nuclear decays that include, for the first time, data from mirror beta transitions. The results confirm the V-A character of the interaction and translate into updated values for V-ud and g(A) at the 10(-4) level. We also place new stringent limits on exotic couplings involving left-handed and right-handed neutrinos, which benefit significantly from the inclusion of mirror decays in the analysis. |
Address |
[Falkowski, Adam] Univ Paris Saclay, CNRS, IN2P3, IJCLab, F-91405 Orsay, France, Email: adam.falkowski@ijclab.in2p3.fr; |
Corporate Author |
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Thesis |
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Publisher |
Springer |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000640519700002 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
4804 |
Permanent link to this record |
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Author |
De Romeri, V.; Martinez-Mirave, P.; Tortola, M. |
Title |
Signatures of primordial black hole dark matter at DUNE and THEIA |
Type |
Journal Article |
Year |
2021 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
Volume |
10 |
Issue |
10 |
Pages |
051 - 21pp |
Keywords |
dark matter theory; neutrino experiments; primordial black holes |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Primordial black holes (PBHs) are a potential dark matter candidate whose masses can span over many orders of magnitude. If they have masses in the 10(15)-10(17) g range, they can emit sizeable fluxes of MeV neutrinos through evaporation via Hawking radiation. We explore the possibility of detecting light (non-)rotating PBHs with future neutrino experiments. We focus on two next generation facilities: the Deep Underground Neutrino Experiment (DUNE) and THEIA. We simulate the expected event spectra at both experiments assuming different PBH mass distributions and spins, and we extract the expected 95% C.L. sensitivities to these scenarios. Our analysis shows that future neutrino experiments like DUNE and THEIA will be able to set competitive constraints on PBH dark matter, thus providing complementary probes in a part of the PBH parameter space currently constrained mainly by photon data. |
Address |
[De Romeri, Valentina] Univ Valencia, Dept Fis Teor, Paterna 46980, Spain, Email: deromeri@ific.uv.es; |
Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000758221400007 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
5140 |
Permanent link to this record |
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Author |
Martinelli, M.; Scarcella, F.; Hogg, N.B.; Kavanagh, B.J.; Gaggero, D.; Fleury, P. |
Title |
Dancing in the dark: detecting a population of distant primordial black holes |
Type |
Journal Article |
Year |
2022 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
Volume |
08 |
Issue |
8 |
Pages |
006 - 47pp |
Keywords |
dark matter theory; gravitational waves / experiments; gravitational waves / sources; primordial black holes |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Primordial black holes (PBHs) are compact objects proposed to have formed in the early Universe from the collapse of small-scale over-densities. Their existence may be detected from the observation of gravitational waves (GWs) emitted by PBH mergers, if the signals can be distinguished from those produced by the merging of astrophysical black holes. In this work, we forecast the capability of the Einstein Telescope, a proposed third-generation GW observatory, to identify and measure the abundance of a subdominant population of distant PBHs, using the difference in the redshift evolution of the merger rate of the two populations as our discriminant. We carefully model the merger rates and generate realistic mock catalogues of the luminosity distances and errors that would be obtained from GW signals observed by the Einstein Telescope. We use two independent statistical methods to analyse the mock data, finding that, with our more powerful, likelihood-based method, PBH abundances as small as fPBH approximate to 7 x 10(-6) ( fPBH approximate to 2 x 10(-6)) would be distinguishable from f(PBH) = 0 at the level of 3 sigma with a one year (ten year) observing run of the Einstein Telescope. Our mock data generation code, darksirens, is fast, easily extendable and publicly available on GitLab. |
Address |
[Martinelli, Matteo] INAF Osservatorio Astron Roma, Via Frascati 33, I-00040 Rome, Italy, Email: matteo.martinelli@inaf.it; |
Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000911612900001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5461 |
Permanent link to this record |
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Author |
Briz, J.A.; Nerio, A.N.; Ballesteros, C.; Borge, M.J.G.; Martinez, P.; Perea, A.; Tavora, V.G.; Tengblad, O.; Ciemala, M.; Maj, A.; Olko, P.; Parol, W.; Pedracka, A.; Sowicki, B.; Zieblinski, M.; Nacher, E. |
Title |
Proton Radiographs Using Position-Sensitive Silicon Detectors and High-Resolution Scintillators |
Type |
Journal Article |
Year |
2022 |
Publication |
IEEE Transactions on Nuclear Science |
Abbreviated Journal |
IEEE Trans. Nucl. Sci. |
Volume |
69 |
Issue |
4 |
Pages |
696-702 |
Keywords |
LaBr3; particle tracking; proton computed tomography (pCT); proton radiograph; proton therapy; scintillation detectors; silicon detectors |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Proton therapy is a cancer treatment technique currently in growth since it offers advantages with respect to conventional X-ray and gamma-ray radiotherapy. In particular, better control of the dose deposition allowing to reach higher conformity in the treatments causing less secondary effects. However, in order to take full advantage of its potential, improvements in treatment planning and dose verification are required. A new prototype of proton computed tomography scanner is proposed to design more accurate and precise treatment plans for proton therapy. Our prototype is formed by double-sided silicon strip detectors and scintillators of LaBr3(Ce) with high energy resolution and fast response. Here, the results obtained from an experiment performed using a 100-MeV proton beam are presented. Proton radiographs of polymethyl methacrylate (PMMA) samples of 50-mm thickness with spatial patterns in aluminum were taken. Their properties were studied, including reproduction of the dimensions, spatial resolution, and sensitivity to different materials. Structures of up to 2 mm are well resolved and the sensitivity of the system was enough to distinguish the thicknesses of 10 mm of aluminum or PMMA. The spatial resolution of the images was 0.3 line pairs per mm (MTF-10%). This constitutes the first step to validate the device as a proton radiography scanner. |
Address |
[Briz, J. A.; Nerio, A. N.; Ballesteros, C.; Borge, M. J. G.; Martinez, P.; Perea, A.; Tavora, V. G.; Tengblad, O.] Inst Estruct Mat CSIC, Madrid 28006, Spain, Email: jose.briz@csic.es |
Corporate Author |
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Thesis |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0018-9499 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000803113800017 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5245 |
Permanent link to this record |
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Author |
Assam, I.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Poppe, B.; Siebert, F.A. |
Title |
Evaluation of dosimetric effects of metallic artifact reduction and tissue assignment on Monte Carlo dose calculations for I-125 prostate implants |
Type |
Journal Article |
Year |
2022 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
Volume |
49 |
Issue |
|
Pages |
6195-6208 |
Keywords |
metallic artifact reduction; Monte Carlo dosimetry; post-implant CT; prostate brachytherapy; tissue assignment schemes; voxelized virtual patient model |
Abstract ![sorted by Abstract field, ascending order (up)](img/sort_asc.gif) |
Purpose Monte Carlo (MC) simulation studies, aimed at evaluating the magnitude of tissue heterogeneity in I-125 prostate permanent seed implant brachytherapy (BT), customarily use clinical post-implant CT images to generate a virtual representation of a realistic patient model (virtual patient model). Metallic artifact reduction (MAR) techniques and tissue assignment schemes (TAS) are implemented on the post-implant CT images to mollify metallic artifacts due to BT seeds and to assign tissue types to the voxels corresponding to the bright seed spots and streaking artifacts, respectively. The objective of this study is to assess the combined influence of MAR and TAS on MC absorbed dose calculations in post-implant CT-based phantoms. The virtual patient models used for I-125 prostate implant MC absorbed dose calculations in this study are derived from the CT images of an external radiotherapy prostate patient without BT seeds and prostatic calcifications, thus averting the need to implement MAR and TAS. Methods The geometry of the IsoSeed I25.S17plus source is validated by comparing the MC calculated results of the TG-43 parameters for the line source approximation with the TG-43U1S2 consensus data. Four MC absorbed dose calculations are performed in two virtual patient models using the egs_brachy MC code: (1) TG-43-based D-w,w-TG(43), (2) D-w,D-w-MBDC that accounts for interseed scattering and attenuation (ISA), (3) D-m,D-m that examines ISA and tissue heterogeneity by scoring absorbed dose in tissue, and (4) D-w,D-m that unlike D-m,D-m scores absorbed dose in water. The MC absorbed doses (1) and (2) are simulated in a TG-43 patient phantom derived by assigning the densities of every voxel to 1.00 g cm(-3) (water), whereas MC absorbed doses (3) and (4) are scored in the TG-186 patient phantom generated by mapping the mass density of each voxel to tissue according to a CT calibration curve. The MC absorbed doses calculated in this study are compared with VariSeed v8.0 calculated absorbed doses. To evaluate the dosimetric effect of MAR and TAS, the MC absorbed doses of this work (independent of MAR and TAS) are compared to the MC absorbed doses of different I-125 source models from previous studies that were calculated with different MC codes using post-implant CT-based phantoms generated by implementing MAR and TAS on post-implant CT images. Results The very good agreement of TG-43 parameters of this study and the published consensus data within 3% validates the geometry of the IsoSeed I25.S17plus source. For the clinical studies, the TG-43-based calculations show a D-90 overestimation of more than 4% compared to the more realistic MC methods due to ISA and tissue composition. The results of this work generally show few discrepancies with the post-implant CT-based dosimetry studies with respect to the D-90 absorbed dose metric parameter. These discrepancies are mainly Type B uncertainties due to the different I-125 source models and MC codes. Conclusions The implementation of MAR and TAS on post-implant CT images have no dosimetric effect on the I-125 prostate MC absorbed dose calculation in post-implant CT-based phantoms. |
Address |
[Assam, Isong; Siebert, Frank-Andre] UKSH, Clin Radiotherapy Radiooncol, Campus Kiel, Kiel, Germany, Email: Isong.Assam@uksh.de |
Corporate Author |
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Thesis |
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Publisher |
Wiley |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0094-2405 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000835807200001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5321 |
Permanent link to this record |