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Author Balibrea-Correa, J.; Lerendegui-Marco, J.; Babiano-Suarez, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros-Rodriguez, P.; Domingo-Pardo, C. url  doi
openurl 
  Title Machine Learning aided 3D-position reconstruction in large LaCl3 crystals Type Journal Article
  Year 2021 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 1001 Issue Pages 165249 - 17pp  
  Keywords Gamma-ray; Position sensitive detectors; Monolithic crystals; Compton imaging; Machine Learning; Convolutional Neural Networks; Total Energy Detector; Neutron capture cross-section  
  Abstract (up) We investigate five different models to reconstruct the 3D gamma-ray hit coordinates in five large LaCl3(Ce) monolithic crystals optically coupled to pixelated silicon photomultipliers. These scintillators have a base surface of 50 x 50 mm(2) and five different thicknesses, from 10 mm to 30 mm. Four of these models are analytical prescriptions and one is based on a Convolutional Neural Network. Average resolutions close to 1-2 mm fwhm are obtained in the transverse crystal plane for crystal thicknesses between 10 mm and 20 mm using analytical models. For thicker crystals average resolutions of about 3-5 mm fwhm are obtained. Depth of interaction resolutions between 1 mm and 4 mm are achieved depending on the distance of the interaction point to the photosensor surface. We propose a Machine Learning algorithm to correct for linearity distortions and pin-cushion effects. The latter allows one to keep a large field of view of about 70%-80% of the crystal surface, regardless of crystal thickness. This work is aimed at optimizing the performance of the so-called Total Energy Detector with Compton imaging capability (i-TED) for time-of-flight neutron capture cross-section measurements.  
  Address [Balibrea-Correa, J.; Lerendegui-Marco, J.; Babiano-Suarez, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros-Rodriguez, P.; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: javier.balibrea@ific.uv.es  
  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000641308300007 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 4803  
Permanent link to this record
 

 
Author Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Nacher, E.; Tain, J.L.; Tolosa, A. url  doi
openurl 
  Title On the performance of large monolithic LaCl3(Ce) crystals coupled to pixelated silicon photosensors Type Journal Article
  Year 2018 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 13 Issue Pages P03014 - 17pp  
  Keywords Compton imaging; Detector modelling and simulations I (interaction of radiation with matter interaction of photons with matter interaction of hadrons with matter etc); Gamma detectors (scintillators CZT HPG HgI etc); Instrumentation and methods for time-of-flight (TOF); spectroscopy  
  Abstract (up) We investigate the performance of large area radiation detectors, with high energy-and spatial-resolution, intended for the development of a Total Energy Detector with gamma-ray imaging capability, so-called i-TED. This new development aims for an enhancement in detection sensitivity in time-of-flight neutron capture measurements, versus the commonly used C6D6 liquid scintillation total-energy detectors. In this work, we study in detail the impact of the readout photosensor on the energy response of large area (50 x 50 mm(2)) monolithic LaCl3(Ce) crystals, in particular when replacing a conventional mono-cathode photomultiplier tube by an 8 x 8 pixelated silicon photomultiplier. Using the largest commercially available monolithic SiPM array (25 cm(2)), with a pixel size of 6 x 6 mm(2), we have measured an average energy resolution of 3.92% FWHM at 662 keV for crystal thick-nesses of 10, 20 and 30 mm. The results are confronted with detailed Monte Carlo (MC) calculations, where optical processes and properties have been included for the reliable tracking of the scintillation photons. After the experimental validation of the MC model, we use our MC code to explore the impact of a smaller photosensor segmentation on the energy resolution. Our optical MC simulations predict only a marginal deterioration of the spectroscopic performance for pixels of 3 x 3 mm(2).  
  Address [Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Tain, J. L.; Tolosa, A.] Univ Valencia, CSIC, Inst Fis Corpuscular, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: Luis.Caballero@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000428146300004 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 3542  
Permanent link to this record
 

 
Author Balibrea-Correa, J.; Lerendegui-Marco, J.; Ladarescu, I.; Guerrero, C.; Rodriguez-Gonzalez, T.; Jimenez-Ramos, M.C.; Fernandez-Martinez, B.; Domingo-Pardo, C. url  doi
openurl 
  Title Hybrid in-beam PET- and Compton prompt-gamma imaging aimed at enhanced proton-range verification Type Journal Article
  Year 2022 Publication European Physical Journal Plus Abbreviated Journal Eur. Phys. J. Plus  
  Volume 137 Issue 11 Pages 1258 - 18pp  
  Keywords  
  Abstract (up) We report on a hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA cyclotron facility using a set of two synchronous Compton imagers and different target materials. The time structure of the 18 MeV proton beam was shaped with a series of beam-on and beam-off intervals, thereby mimicking a pulsed proton beam on a long time scale. During beam-on intervals, Compton imagingwas performed utilizing the high energy. -rays promptly emitted from the nuclear reactions occurring in the targets. In the course of the beam-off intervals in situ positron-emission tomography was accomplished with the same imagers using the beta+ decay of activated nuclei. The targets used were stacks of different materials covering also various proton ranges and energies. A systematic study on the performance of these two complementary imaging techniques is reported and the experimental results interpreted on the basis ofMonte Carlo calculations. The results demonstrate the possibility to combine both imaging techniques in a concomitant way, where high-efficiency prompt-gamma imaging is complemented with the high spatial accuracy of PET. Empowered by these results we suggest that a pulsed beam with a suitable duty cycle, in conjunction with in situ Compton- and PET-imaging may help to attain complementary information and quasi real-time range monitoring with high accuracy.  
  Address [Balibrea-Correa, J.; Lerendegui-Marco, J.; Ladarescu, I; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: javier.balibrea@ific.uv.es  
  Corporate Author Thesis  
  Publisher Springer Heidelberg Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2190-5444 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000886327900002 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5420  
Permanent link to this record
 

 
Author Babiano, V.; Caballero, L.; Calvo, D.; Ladarescu, I.; Olleros, P.; Domingo-Pardo, C. url  doi
openurl 
  Title gamma-Ray position reconstruction in large monolithic LaCl3(Ce) crystals with SiPM readout Type Journal Article
  Year 2019 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 931 Issue Pages 1-22  
  Keywords Gamma-ray; Position-sensitive detectors; Monolithic crystals; Spatial resolution; Neural networks  
  Abstract (up) We report on the spatial response characterization of large LaCl3(Ce) monolithic crystals optically coupled to 8 x 8 pixel silicon photomultiplier (SiPM) sensors. A systematic study has been carried out for 511 keV gamma-rays using three different crystal thicknesses of 10 mm, 20 mm and 30 mm, all of them with planar geometry and a base size of 50 x 50 mm(2). In this work we investigate and compare two different approaches for the determination of the main gamma-ray hit location. On one hand, methods based on the fit of an analytical model for the scintillation light distribution provide the best results in terms of linearity and field of view, with spatial resolutions close to similar to 1 mm FWHM. On the other hand, position reconstruction techniques based on neural networks provide similar linearity and field-of-view, becoming the attainable spatial resolution similar to 3 mm FWHM. For the third space coordinate z or depth-of-interaction we have implemented an inverse linear calibration approach based on the cross-section of the measured scintillation-light distribution at a certain height. The detectors characterized in this work are intended for the development of so-called Total Energy Detectors with Compton imaging capability (i-TED), aimed at enhanced sensitivity and selectivity measurements of neutron capture cross sections via the time-of-flight (TOF) technique.  
  Address [Babiano, V; Caballero, L.; Calvo, D.; Ladarescu, I; Olleros, P.; Domingo-Pardo, C.] Univ Valencia, Inst Fis Corpuscular, CSIC, Valencia, Spain, Email: domingo@ific.uv.es  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000466151600001 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 4015  
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