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Author |
Fletcher, E.M.; Ballester, F.; Beaulieu, L.; Morrison, H.; Poher, A.; Rivard, M.J.; Sloboda, R.S.; Vijande, J.; Thomson, R.M. |
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Title |
Generation and comparison of 3D dosimetric reference datasets for COMS eye plaque brachytherapy using model-based dose calculations |
Type |
Journal Article |
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Year |
2024 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
51 |
Issue |
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Pages |
694-706 |
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Keywords |
Monte Carlo; ocular brachytherapy; treatment planning |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
PurposeA joint Working Group of the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) was created to aid in the transition from the AAPM TG-43 dose calculation formalism, the current standard, to model-based dose calculations. This work establishes the first test cases for low-energy photon-emitting brachytherapy using model-based dose calculation algorithms (MBDCAs).Acquisition and Validation MethodsFive test cases are developed: (1) a single model 6711 125I brachytherapy seed in water, 13 seeds (2) individually and (3) in combination in water, (4) the full Collaborative Ocular Melanoma Study (COMS) 16-mm eye plaque in water, and (5) the full plaque in a realistic eye phantom. Calculations are done with four Monte Carlo (MC) codes and a research version of a commercial treatment planning system (TPS). For all test cases, local agreement of MC codes was within & SIM;2.5% and global agreement was & SIM;2% (4% for test case 5). MC agreement was within expected uncertainties. Local agreement of TPS with MC was within 5% for test case 1 and & SIM;20% for test cases 4 and 5, and global agreement was within 0.4% for test case 1 and 10% for test cases 4 and 5.Data Format and Usage NotesDose distributions for each set of MC and TPS calculations are available online () along with input files and all other information necessary to repeat the calculations.Potential ApplicationsThese data can be used to support commissioning of MBDCAs for low-energy brachytherapy as recommended by TGs 186 and 221 and AAPM Report 372. This work additionally lays out a sample framework for the development of test cases that can be extended to other applications beyond eye plaque brachytherapy. |
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Address |
[Fletcher, Elizabeth M.; Thomson, Rowan M.] Carleton Univ, Phys Dept, Carleton Lab Radiotherapy Phys, Ottawa, ON, Canada, Email: rthomson@physics.carleton.ca |
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Wiley |
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English |
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0094-2405 |
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Notes |
WOS:001058112300001 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5632 |
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Author |
Baran, J. et al; Brzezinski, K. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Feasibility of the J-PET to monitor the range of therapeutic proton beams |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physica Medica |
Abbreviated Journal |
Phys. Medica |
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Volume |
118 |
Issue |
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Pages |
103301 - 9pp |
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Keywords |
PET; Range monitoring; J-PET; Monte Carlo simulations; Proton radiotherapy |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Purpose: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J -PET) scanner for intra-treatment proton beam range monitoring. Methods: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J -PET scanner geometries. We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread -Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J -PET scanner prototype dedicated to the proton beam range assessment. Results: The investigations indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10-5 coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple -layer dual -head geometry. The results indicate that the double -layer cylindrical and triple -layer double -head configurations are the most promising for the clinical application, Conclusions: We performed simulation studies demonstrating that the feasibility of the J -PET detector for PET -based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre -clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double -layer cylindrical and triple -layer dual -head J -PET geometry configurations seem promising for future clinical application. |
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[Baran, Jakub; Silarski, Michal; Chug, Neha; Coussat, Aurelien; Czerwinski, Eryk; Dadgar, Meysam; Dulski, Kamil; Eliyan, Kavya, V; Gajos, Aleksander; Kacprzak, Krzysztof; Kaplon, Lukasz; Korcyl, Grzegorz; Kozik, Tomasz; Kumar, Deepak; Niedzwiecki, Szymon; Panek, Dominik; Parzych, Szymon; del Rio, Elena Perez; Simbarashe, Moyo; Sharma, Sushil; Shivani; Skurzok, Magdalena; Stepien, Ewa L.; Tayefi, Keyvan; Tayefi, Faranak; Moskal, Pawel] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, 11 Lojasiewicza St, PL-30348 Krakow, Poland, Email: jakubbaran92@gmail.com |
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Elsevier Sci Ltd |
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English |
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1120-1797 |
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Notes |
WOS:001178648400001 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5990 |
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Author |
Centelles Chulia, S.; Miranda, O.G.; Valle, J.W.F. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Leptonic neutral-current probes in a short-distance DUNE-like setup |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
11 |
Pages |
115007 - 12pp |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Precision measurements of neutrino -electron scattering may provide a viable way to test the nonminimal form of the charged and neutral current weak interactions within a hypothetical near -detector setup for the Deep Underground Neutrino Experiment (DUNE). Although low -statistics, these processes are clean and provide information complementing the results derived from oscillation studies. They could shed light on the scale of neutrino mass generation in low -scale seesaw schemes. |
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[Chulia, Salvador Centelles] Max Planck Inst Kernphys, Saupfercheckweg 1, D-69117 Heidelberg, Germany, Email: chulia@mpi-hd.mpg.de; |
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Amer Physical Soc |
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2470-0010 |
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Notes |
WOS:001243878300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6146 |
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Author |
Fajfer, S.; Solomonidi, E.; Vale Silva, L. |
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Title |
S-wave contribution to rare D0 → π+ π- l+ l- decays in the standard model and sensitivity to new physics |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
3 |
Pages |
036027 - 24pp |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
Physics of the up-type flavor offers unique possibilities of testing the standard model (SM) compared to the down-type flavor sector. Here, we discuss SM and new physics (NP) contributions to the rare charmmeson decay D0 -> x+x- l+l-. In particular, we discuss the effect of including the lightest scalar isoscalar resonance in the SM picture, namely, the f0(500), which manifests in a big portion of the allowed phase space. Other than showing in the total branching ratio at an observable level of about 20%, the f0(500) resonance manifests as interference terms with the vector resonances, such as at high invariant mass of the leptonic pair in distinct angular observables. Recent data from LHCb optimize the sensitivity to P-wave contributions that we analyze in view of the inclusion of vector resonances. We propose the measurement of alternative observables that are sensitive to the S-wave and are straightforward to implement experimentally. This leads to a new set of null observables that vanish in the SM due to its gauge and flavor structures. Finally, we study observables that depend on the SM interference with generic NP contributions from semileptonic four-fermion operators in the presence of the S-wave. |
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[Fajfer, Svjetlana] Jozef Stefan Inst, Jamova 39,POB 3000, Ljubljana 1001, Slovenia |
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Amer Physical Soc |
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English |
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2470-0010 |
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Notes |
WOS:001181678500001 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5991 |
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Author |
Hajjar, R.; Palomares-Ruiz, S.; Mena, O. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Shedding light on the Δm21^2 tension with supernova neutrinos |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
854 |
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138719 - 8pp |
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Abstract ![sorted by Abstract field, descending order (down)](img/sort_desc.gif) |
One long-standing tension in the determination of neutrino parameters is the mismatched value of the solar mass square difference, Delta m(21)(2), measured by different experiments: the reactor antineutrino experiment KamLAND finds a best fit larger than the one obtained with solar neutrino data. Even if the current tension is mild (similar to 1.5 sigma.), it is timely to explore if independent measurements could help in either closing or reassessing this issue. In this regard, we explore how a future supernova burst in our galaxy could be used to determine Delta m(21)(2) at the future Hyper-Kamiokande detector, and how this could contribute to the current situation. We study Earth matter effects for different models of supernova neutrino spectra and supernova orientations. We find that, if supernova neutrino data prefers the KamLAND best fit for Delta m(21)(2), an uncertainty similar to the current KamLAND one could be achieved. On the contrary, if it prefers the solar neutrino data best fit, the current tension with KamLAND results could grow to a significance larger than 5 sigma. Furthermore, supernova neutrinos could significantly contribute to reducing the uncertainty on sin (2)theta(12). |
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Address |
[Hajjar, Rasmi; Palomares-Ruiz, Sergio; Mena, Olga] Univ Valencia, CSIC, Inst Fis Corpuscular IFIC, Parc Cientif UV, C-Catedrat Jose Beltran 2, E-46980 Paterna, Spain, Email: rasmi.hajjar@ific.uv.es; |
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Publisher |
Elsevier |
Place of Publication |
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English |
Summary Language |
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ISSN |
0370-2693 |
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Notes |
WOS:001246913500002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6159 |
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Permanent link to this record |