Records |
Author |
Borys, D. et al; Brzezinski, K. |
Title |
ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging |
Type |
Journal Article |
Year |
2022 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume |
67 |
Issue |
22 |
Pages |
224002 - 15pp |
Keywords |
proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging |
Abstract |
Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022). |
Address |
[Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl |
Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000885248200001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
5416 |
Permanent link to this record |
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Author |
Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G. |
Title |
Joint image reconstruction algorithm in Compton cameras |
Type |
Journal Article |
Year |
2022 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
Volume |
67 |
Issue |
15 |
Pages |
155009 - 15pp |
Keywords |
Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope |
Abstract |
Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging. |
Address |
[Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es |
Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000827830200001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
no |
Call Number |
IFIC @ pastor @ |
Serial |
5298 |
Permanent link to this record |
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Author |
Giare, W.; Renzi, F.; Melchiorri, A.; Mena, O.; Di Valentino, E. |
Title |
Cosmological forecasts on thermal axions, relic neutrinos, and light elements |
Type |
Journal Article |
Year |
2022 |
Publication |
Monthly Notices of the Royal Astronomical Society |
Abbreviated Journal |
Mon. Not. Roy. Astron. Soc. |
Volume |
511 |
Issue |
1 |
Pages |
1373-1382 |
Keywords |
cosmic background radiation; cosmological parameters; dark matter; early Universe; cosmology: observations |
Abstract |
One of the targets of future cosmic microwave background (CMB) and baryon acoustic oscillation measurements is to improve the current accuracy in the neutrino sector and reach a much better sensitivity on extra dark radiation in the early Universe. In this paper, we study how these improvements can be translated into constraining power for well-motivated extensions of the standard model of elementary particles that involve axions thermalized before the quantum chromodynamics (QCD) phase transition by scatterings with gluons. Assuming a fiducial Lambda cold dark matter cosmological model, we simulate future data for Stage-IV CMB-like and Dark Energy Spectroscopic Instrument (DESI)-like surveys and analyse a mixed scenario of axion and neutrino hot dark matter. We further account also for the effects of these QCD axions on the light element abundances predicted by big bang nucleosynthesis. The most constraining forecasted limits on the hot relic masses are m(a) less than or similar to 0.92 eV and n-ary sumation m(nu) less than or similar to 0.12 eV at 95 per cent Confidence Level, showing that future cosmic observations can substantially improve the current bounds, supporting multimessenger analyses of axion, neutrino, and primordial light element properties. |
Address |
[Giare, William; Melchiorri, Alessandro] Univ Roma La Sapienza, Phys Dept, Ple Aldo Moro 2, I-00185 Rome, Italy, Email: william.giare@gmail.com |
Corporate Author |
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Thesis |
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Publisher |
Oxford Univ Press |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0035-8711 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000770034000012 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5192 |
Permanent link to this record |
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Author |
PANDA Collaboration (Davi, F. et al); Diaz, J. |
Title |
Technical design report for the endcap disc DIRC |
Type |
Journal Article |
Year |
2022 |
Publication |
Journal of Physics G |
Abbreviated Journal |
J. Phys. G |
Volume |
49 |
Issue |
12 |
Pages |
120501 - 128pp |
Keywords |
technical design report; particle identification; Cherenkov detector; PANDA |
Abstract |
PANDA (anti-proton annihiliation at Darmstadt) is planned to be one of the four main experiments at the future international accelerator complex FAIR (Facility for Antiproton and Ion Research) in Darmstadt, Germany. It is going to address fundamental questions of hadron physics and quantum chromodynamics using cooled antiproton beams with a high intensity and and momenta between 1.5 and 15 GeV/c. PANDA is designed to reach a maximum luminosity of 2 x 10(32) cm(-2) s. Most of the physics programs require an excellent particle identification (PID). The PID of hadronic states at the forward endcap of the target spectrometer will be done by a fast and compact Cherenkov detector that uses the detection of internally reflected Cherenkov light (DIRC) principle. It is designed to cover the polar angle range from 5 degrees to 22 degrees and to provide a separation power for the separation of charged pions and kaons up to 3 standard deviations (s.d.) for particle momenta up to 4 GeV/c in order to cover the important particle phase space. This document describes the technical design and the expected performance of the novel PANDA disc DIRC detector that has not been used in any other high energy physics experiment before. The performance has been studied with Monte-Carlo simulations and various beam tests at DESY and CERN. The final design meets all PANDA requirements and guarantees sufficient safety margins. |
Address |
[Davi, F.] Univ Politecn Marche Ancona, Ancona, Italy, Email: muschmidt@uni-wuppertal.de |
Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0954-3899 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000928188400001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5476 |
Permanent link to this record |
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Author |
AbdusSalam, S.S. et al; Eberhardt, O. |
Title |
Simple and statistically sound recommendations for analysing physical theories |
Type |
Journal Article |
Year |
2022 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
Volume |
85 |
Issue |
5 |
Pages |
052201 - 11pp |
Keywords |
particle physics; statistics; methodology |
Abstract |
Physical theories that depend on many parameters or are tested against data from many different experiments pose unique challenges to statistical inference. Many models in particle physics, astrophysics and cosmology fall into one or both of these categories. These issues are often sidestepped with statistically unsound ad hoc methods, involving intersection of parameter intervals estimated by multiple experiments, and random or grid sampling of model parameters. Whilst these methods are easy to apply, they exhibit pathologies even in low-dimensional parameter spaces, and quickly become problematic to use and interpret in higher dimensions. In this article we give clear guidance for going beyond these procedures, suggesting where possible simple methods for performing statistically sound inference, and recommendations of readily-available software tools and standards that can assist in doing so. Our aim is to provide any physicists lacking comprehensive statistical training with recommendations for reaching correct scientific conclusions, with only a modest increase in analysis burden. Our examples can be reproduced with the code publicly available at Zenodo. |
Address |
[AbdusSalam, Shehu S.; Fowlie, Andrew] Shahid Beheshti Univ, Dept Phys, Tehran, Iran, Email: andrew.j.fowlie@njnu.edu.cn |
Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0034-4885 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000791574900001 |
Approved |
no |
Is ISI |
yes |
International Collaboration |
yes |
Call Number |
IFIC @ pastor @ |
Serial |
5221 |
Permanent link to this record |