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Babiano-Suarez, V. et al; Lerendegui-Marco, J.; Balibrea-Correa, J.; Caballero, L.; Calvo, D.; Ladarescu, I.; Real, D.; Domingo-Pardo, C. |
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Title |
Imaging neutron capture cross sections: i-TED proof-of-concept and future prospects based on Machine-Learning techniques |
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Journal Article |
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Year |
2021 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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57 |
Issue |
6 |
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197 - 17pp |
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Abstract  |
i-TED is an innovative detection system which exploits Compton imaging techniques to achieve a superior signal-to-background ratio in (n, gamma) cross-section measurements using time-of-flight technique. This work presents the first experimental validation of the i-TED apparatus for high-resolution time-of-flight experiments and demonstrates for the first time the concept proposed for background rejection. To this aim, the Au-197(n, gamma) and Fe-56(n, gamma) reactions were studied at CERN n_TOF using an i-TED demonstrator based on three position-sensitive detectors. Two C6D6 detectors were also used to benchmark the performance of i-TED. The i-TED prototype built for this study shows a factor of similar to 3 higher detection sensitivity than state-of-the-art C6D6 detectors in the 10 keV neutron-energy region of astrophysical interest. This paper explores also the perspectives of further enhancement in performance attainable with the final i-TED array consisting of twenty position-sensitive detectors and newanalysis methodologies based on Machine-Learning techniques. |
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1434-6001 |
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WOS:000662881100001 |
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no |
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yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4875 |
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Author |
Lerendegui-Marco, J.; Balibrea-Correa, J.; Babiano-Suarez, V.; Ladarescu, I.; Domingo-Pardo, C. |
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Title |
Towards machine learning aided real-time range imaging in proton therapy |
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Journal Article |
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Year |
2022 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
12 |
Issue |
1 |
Pages |
2735 - 17pp |
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Abstract |
Compton imaging represents a promising technique for range verification in proton therapy treatments. In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by gamma-ray energies spanning up to 5-6 MeV, rather low gamma-ray emission yields and very intense neutron induced gamma-ray backgrounds. Our developments to cope with these three aspects are concomitant with those required in the field of hadron therapy, especially in terms of high efficiency for real-time monitoring, low sensitivity to neutron backgrounds and reliable performance at the high gamma-ray energies. We find that signal-to-background ratios can be appreciably improved with i-TED thanks to its light-weight design and the low neutron-capture cross sections of its LaCl3 crystals, when compared to other similar systems based on LYSO, CdZnTe or LaBr3. Its high time-resolution (CRT similar to 500 ps) represents an additional advantage for background suppression when operated in pulsed HT mode. Each i-TED Compton module features two detection planes of very large LaCl3 monolithic crystals, thereby achieving a high efficiency in coincidence of 0.2% for a point-like 1 MeV gamma-ray source at 5 cm distance. This leads to sufficient statistics for reliable image reconstruction with an array of four i-TED detectors assuming clinical intensities of 10(8) protons per treatment point. The use of a two-plane design instead of three-planes has been preferred owing to the higher attainable efficiency for double time-coincidences than for threefold events. The loss of full-energy events for high energy gamma-rays is compensated by means of machine-learning based algorithms, which allow one to enhance the signal-to-total ratio up to a factor of 2. |
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[Lerendegui-Marco, Jorge; Balibrea-Correa, Javier; Babiano-Suarez, Victor; Ladarescu, Ion; Domingo-Pardo, Cesar] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: jorge.lerendegui@ific.uv.es |
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Nature Portfolio |
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English |
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2045-2322 |
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WOS:000757537100018 |
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no |
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Is ISI |
yes |
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no |
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Call Number |
IFIC @ pastor @ |
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5136 |
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Chiera, N.M.; Maugeri, E.A.; Danilov, I.; Balibrea-Correa, J.; Domingo-Pardo, C.; Koster, U.; Lerendegui-Marco, J.; Veicht, M.; Zivadinovic, I.; Schumann, D. |
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Title |
Preparation of PbSe targets for Se-79 neutron capture cross section studies |
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Journal Article |
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2022 |
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Nuclear Instruments & Methods in Physics Research A |
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Nucl. Instrum. Methods Phys. Res. A |
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1029 |
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166443 - 7pp |
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Keywords |
Lead selenide; Selenium-79; Neutron capture; PbSe target; Se separation |
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Abstract |
A methodology for the production of PbSe targets for Se-79 neutron capture cross section studies is presented. PbSe material was synthesized by direct reaction of its constituents at high temperature, and characterized by X-ray diffraction. Thin PbSe targets, produced for cross section experiments with the surrogate reaction method, were obtained by applying a physical vapor deposition technique, and their morphology and composition were analyzed by X-ray fluorescence, Scanning Electron Microscopy, and Energy dispersive X-ray spectroscopy. (PbSe)-Se-79 targets produced for cross section measurements with the Time of Flight method were characterized by gamma-ray spectroscopy. Finally, a procedure for the recovery of Se from PbSe is suggested. The purity of the retrieved Se was determined with Inductively Coupled Plasma Optical Emission Spectroscopy. |
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[Chiera, Nadine M.; Maugeri, Emilio Andrea; Danilov, Ivan; Veicht, Mario; Zivadinovic, Ivan; Schumann, Dorothea] Paul Scherrer Inst, Villigen, Switzerland, Email: nadine-mariel.chiera@psi.ch |
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Elsevier |
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English |
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0168-9002 |
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WOS:000783012200016 |
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no |
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yes |
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no |
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Call Number |
IFIC @ pastor @ |
Serial |
5204 |
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