Abstract: Symmetries in the Physical Laws of Nature lead to observable effects. Beyond the regularities and conserved magnitudes, the last few decades in particle physics have seen the identification of symmetries, and their well-defined breaking, as the guiding principle for the elementary constituents of matter and their interactions. Flavour SU(3) symmetry of hadrons led to the Quark Model and the antisymmetric requirement under exchange of identical fermions led to the colour degree of freedom. Colour became the generating charge for flavour-independent strong interactions of quarks and gluons in the exact colour SU(3) local gauge symmetry. Parity Violation in weak interactions led us to consider the chiral fields of fermions as the objects with definite transformation properties under the weak isospin SU(2) gauge group of the Unifying Electro-Weak SU(2) x U(1) symmetry, which predicted novel weak neutral current interactions. CP-Violation led to three families of quarks opening the field of Flavour Physics. Time-reversal violation has recently been observed with entangled neutral mesons, compatible with CPT-invariance. The cancellation of gauge anomalies, which would invalidate the gauge symmetry of the quantum field theory, led to Quark-Lepton Symmetry. Neutrinos were postulated in order to save the conservation laws of energy and angular momentum in nuclear beta decay. After the ups and downs of their mass, neutrino oscillations were discovered in 1998, opening a new era about their origin of mass, mixing, discrete symmetries and the possibility of global lepton-number violation through Majorana mass terms and Leptogenesis as the source of the matter-antimatter asymmetry in the universe. The experimental discovery of quarks and leptons and the mediators of their interactions, with physical observables in spectacular agreement with this Standard Theory, is the triumph of Symmetries. The gauge symmetry is exact only when the particles are massless. One needs a subtle breaking of the symmetry, providing the origin of mass without affecting the excellent description of the interactions. This is the Brout-Englert-Higgs Mechanism, which produces the Higgs Boson as a remnant, discovered at CERN in 2012. Open present problems are addressed with by searching the New Physics Beyond-the-Standard-Model.

Abstract: Neutrinos are the only particles in the Standard Model that could be Majorana fermions, that is, completely neutral fermions that are their own antiparticles. The most sensitive known experimental method to verify whether neutrinos are Majorana particles is the search for neutrinoless double-beta decay. The last 2 decades have witnessed the development of a vigorous program of neutrinoless double-beta decay experiments, spanning several isotopes and developing different strategies to handle the backgrounds masking a possible signal. In addition, remarkable progress has been made in the understanding of the nuclear matrix elements of neutrinoless double-beta decay, thus reducing a substantial part of the theoretical uncertainties affecting the particle-physics interpretation of the process. On the other hand, the negative results by several experiments, combined with the hints that the neutrino mass ordering could be normal, may imply very long lifetimes for the neutrinoless double-beta decay process. In this report, we review the main aspects of such process, the recent progress on theoretical ideas and the experimental state of the art. We then consider the experimental challenges to be addressed to increase the sensitivity to detect the process in the likely case that lifetimes are much longer than currently explored, and discuss a selection of the most promising experimental efforts.