Abstract: This article reports the laser calibration of the hadronic Tile Calorimeter of the ATLAS experiment in the LHC Run 2 data campaign. The upgraded Laser II calibration system is described. The system was commissioned during the first LHC Long Shutdown, exhibiting a stability better than 0.8% for the laser light monitoring. The methods employed to derive the detector calibration factors with data from the laser calibration runs are also detailed. These allowed to correct for the response fluctuations of the 9852 photomultiplier tubes of the Tile Calorimeter with a total uncertainty of 0.5% plus a luminosity-dependent sub-dominant term. Finally, we report the regular monitoring and performance studies using laser events in both standalone runs and during proton collisions. These studies include channel timing and quality inspection, and photomultiplier linearity and response dependence on anode current.

Abstract: Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value.

Abstract: In this paper, we present steady-state relativistic magnetohydrodynamic simulations that include a mass-load term to study the process of jet deceleration. The mass load mimics the injection of a proton-electron plasma from stellar winds within the host galaxy into initially pair plasma jets, with mean stellar mass-losses ranging from 10(-14) to 10(-9) M-circle dot yr(-1). The spatial jet evolution covers similar to 500 pc from jet injection in the grid at 10 pc from the jet nozzle. Our simulations use a relativistic gas equation of state and a pressure profile for the ambient medium. We compare these simulations with previous dynamical simulations of relativistic, non-magnetized jets. Our results show that toroidal magnetic fields can prevent fast jet expansion and the subsequent embedding of further stars via magnetic tension. In this sense, magnetic fields avoid a runaway deceleration process. Furthermore, when the mass load is large enough to increase the jet density and produce fast, differential jet expansion, the conversion of magnetic energy flux into kinetic energy flux (i.e. magnetic acceleration), helps to delay the deceleration process with respect to non-magnetized jets. We conclude that the typical stellar population in elliptical galaxies cannot explain jet deceleration in classical Fanaroff-Riley type I radio galaxies. However, we observe a significant change in the jet composition, thermodynamical parameters, and energy dissipation along its evolution, even for moderate values of the mass load.

Abstract: The next core-collapse supernova in the Milky Way or its satellites will represent a once-in-a-generation opportunity to obtain detailed information about the explosion of a star and provide significant scientific insight for a variety of fields because of the extreme conditions found within. Supernovae in our galaxy are not only rare on a human timescale but also happen at unscheduled times, so it is crucial to be ready and use all available instruments to capture all possible information from the event. The first indication of a potential stellar explosion will be the arrival of a bright burst of neutrinos. Its observation by multiple detectors worldwide can provide an early warning for the subsequent electromagnetic fireworks, as well as signal to other detectors with significant backgrounds so they can store their recent data. The supernova early warning system (SNEWS) has been operating as a simple coincidence between neutrino experiments in automated mode since 2005. In the current era of multi-messenger astronomy there are new opportunities for SNEWS to optimize sensitivity to science from the next galactic supernova beyond the simple early alert. This document is the product of a workshop in June 2019 towards design of SNEWS 2.0, an upgraded SNEWS with enhanced capabilities exploiting the unique advantages of prompt neutrino detection to maximize the science gained from such a valuable event.

Abstract: NEXT is a new experiment to search for neutrinoless double beta decay using a 100 kg radio-pure high-pressure gaseous xenon TPC with electroluminescence readout. A large-scale prototype with a SiPM tracking plane has been built. The primary electron paths can be reconstructed from time-resolved measurements of the light that arrives to the SiPM plane. Our approach is to measure how many photons have reached each SiPM sensor each microsecond with a gated integrator. We have designed and tested a 16-channel front-end board that includes the analog paths and a digital section. Each analog path consists of three different stages: a transimpedance amplifier, a gated integrator and an offset and gain control stage. Measurements show good linearity and the ability to detect single photoelectrons.